2015, Número 4
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Rev Mex Med Repro 2015; 7.8 (4)
Aspectos fisiopatológicos y repercusiones reproductivas de los endometriomas ováricos
García-Luna González-Rubio A, Preciado-Ruiz R, García Luna-Vásquez A, Rodríguez-Guerrero RE, Castro-Gordo MM
Idioma: Español
Referencias bibliográficas: 46
Paginas: 145-152
Archivo PDF: 413.96 Kb.
RESUMEN
Existen diversas teorías para explicar la formación del endometrioma ovárico. Quizá la más aceptada es la de la invaginación de la corteza ovárica que forma un pseudoquiste, que explica parcialmente la génesis de los endometriomas. Existe evidencia de efectos negativos del endometrioma en los ovocitos circundantes. En relación con el tratamiento profertilidad de los endometriomas, al parecer la cistectomía del endometrioma tiene mejores resultados en cuanto a menor recurrencia, disminución del dolor y probabilidad de embarazo, comparada con el drenaje y ablación de los implantes endometriósicos. La superficie externa y la cápsula del endometrioma regularmente contienen folículos ováricos, por lo que su excéresis potencialmente puede disminuir la reserva ovárica e incrementar el riesgo de insuficiencia ovárica prematura. Se necesitan más estudios de la fisiopatología del endometrioma para desarrollar mejores líneas de tratamiento.
REFERENCIAS (EN ESTE ARTÍCULO)
Brosens I, et al. History of endometriosis. In endometriosis: science and practice. Giudice LC, et al. editors. Wiley-Blackwell; 2012;113.
Sampson JA. Perforating hemorrhagic (Chocolate) cysts of the ovary. Arch Surg 1921;3:245.Nisolle M.; Fertil Steril, 68:565, 1997
Hughesdon PE. The structure of endometrial cysts of the ovary. J Obstet Gynaecol Br Emp 1957;64:481-487.
Nisolle M, Donnez J. Peritoneal endometriosis, ovarian endometriosis, and adenomyotic nodules of the rectovaginal septum are three different entities. Fertil Steril 1997;68:585-596.
Nezhat F, Nezhat C, Allan CJ, Metzger DA, Sears DL. Clinical and histologic classification of endometriomas. Implications for a mechanism of pathogenesis. J Reprod Med 1992;37:771-776.
Roman H, Tarta O, Pura I, Opris I, et al. Direct proportional relationship between endometrioma size and ovarian parenchyma inadvertently removed during cystectomy, and its implication on the management of enlarged endometriomas. Hum Reprod 2010;25:1428-1432. doi: 10.1093/humrep/deq069. Epub 2010 Apr 8.
Scurry J, Whitehead J, Healey M. Classification of ovarian endometriotic cysts. Int J Gynecol Pathol 2001;20:147-154.
Filippi F, Benaglia L, Paffoni A, Restelli L, et al. Ovarian endometriomas and oocyte quality: insights from in vitro fertilization cycles. Fertil Steril 2014;101:988.
Esinler I, Bozdag G, Arikan I, Demir B, Yarali H. Endometrioma ≤3 cm in diameter per se does not affect ovarian reserve in intracytoplasmic sperm injection cycles. Gynecol Obstet Invest 2012;74:261-264. doi: 10.1159/000339630. Epub 2012 Jul 10.
Suzuki T, Izumi S, Matsubayashi H, Awaji H, et al. Impact of ovarian endometrioma on oocytes and pregnancy outcome in in vitro fertilization. Fertil Steril 2005;83:908-913.
Benaglia L, Bermejo A, Somigliana E, Faulisi S, et al. In vitro fertilization outcome in women with unoperated bilateral endometriomas. Fertil Steril 2013;99:1714-1719. doi: 10.1016/j.fertnstert.2013.01.110. Epub 2013 Feb 15.
Ashrafi M, Fakheri T, Kiani K, Sadeghi M, Akhoond MR. Impact of the endometrioma on ovarian response and pregnancy rate in in vitro fertilization cycles. Int J Fertil Steril 2014;8:29-34. Epub 2014 Mar 9.
Gianaroli L, Racowsky C, Geraedts J, Cedars M, et al. Best practices of ASRM and ESHRE: a journey through reproductive medicine. Fertil Steril. 2012;98:1380-1394. doi: 10.1016/j.fertnstert.2012.07.1164. Epub 2012 Oct 24.
Gianaroli L, Racowsky C, Geraedts J, Cedars M, et al. Best practices of ASRM and ESHRE: a journey through reproductive medicine. Hum Reprod 2012;27:3365-3379. doi: 10.1093/humrep/des338. Epub 2012 Oct 23.
Opøien HK1, Fedorcsak P, Omland AK, Abyholm T, et al. In vitro fertilization is a successful treatment in endometriosis- associated infertility. Fertil Steril 2012;97:912-918. doi: 10.1016/j.fertnstert.2012.01.112. Epub 2012 Feb 15.
Sanchez AM, Viganò P, Somigliana E, Cioffi R, et al. The endometriotic tissue lining the internal surface of endometrioma: hormonal, genetic, epigenetic status, and gene expression profile. Reprod Sci 2015;22:391-401. Epub ahead of print
Sanchez AM, Papaleo E, Corti L, Santambrogio P, et al. Iron availability is increased in individual human ovarian follicles in close proximity to an endometrioma compared with distal ones. Hum Reprod 2014;29:577-583. doi: 10.1093/humrep/det466. Epub 2014 Jan 15
Bulun SE. Ovarian endometriosis: the nemesis of eggs. Fertil Steril 2014;101:938-939.doi: 10.1016/j.fertnstert. 2014.01.044. Epub 2014 Mar 6.
Kitajima M, Dolmans MM, Donnez O, Masuzaki H, et al. Enhanced follicular recruitment and atresia in cortex derived from ovaries with endometriomas. Fertil Steril. 2014;101:1031-1037. doi: 10.1016/j.fertnstert. 2013.12.049. Epub 2014 Feb 4
Brown J, Farquhar C. Endometriosis: an overview of Cochrane Reviews. Cochrane Database Syst Rev 2014;3:CD009590. doi: 10.1002/14651858.CD009590.pub2.
Donnez J, Wyns C, Nisolle M. Does ovarian surgery for endometriomas impair the ovarian response to gonadotropin? Fertil Steril 2001;76:662-665.
Jones KD, Sutton CJ. Recurrence of chocolate cysts after laparoscopic ablation. J Am Assoc Gynecol Laparosc 2002;9:315-320.
Roman H, Pura I, Tarta O, Mokdad C, et al. Vaporization of ovarian endometrioma using plasma energy: histologic findings of a pilot study. Fertil Steril 2011;95:1853-1856
Auber M, Bourdel N, Mokdad C, Martin C, et al. Ultrasound ovarian assessments after endometrioma ablation using plasma energy. Fertil Steril 2011;95:2621-2624.
Carmona F, Martínez-Zamora MA, Rabanal A, Martínez-Román S, Balasch J. Ovarian cystectomy versus laser vaporization in the treatment of ovarian endometriomas: a randomized clinical trial with a five-year follow-up. Fertil Steril 2011;96:251-254.
Brosens I, Puttemans P, Gordts S, Campo R, et al.. Early stage management of ovarian endometrioma to prevent infertility. Facts Views Vis Obgyn 2013;5:309-314.
Reich H, McGlynn F. Treatment of ovarian endometriomas using laparoscopic surgical techniques. J Reprod Med 1986;31:577-584.
Vercellini P, Chapron C, De Giorgi O, Consonni D, et al. Coagulation or excision of ovarian endometriomas? Am J Obstet Gynecol 2003;188:606-610.
Ercan CM, Sakinci M, Duru NK, et al. Antimullerian hormone levels after laparoscopic endometrioma stripping surgery. Gynaecological Endocrinol 2010;26:468-472.
Hart RJ, Hickey M, Maouris P, Buckett W, Garry R. Excisional surgery versus ablative surgery for ovarian endometriomata. Cochrane Database Syst Rev 2005;3:CD004992.
Alborzi S, Momtahan M, Parsanezhad ME, Dehbashi S, et al. A prospective, randomized study comparing laparoscopic ovarian cystectomy versus fenestration and coagulation in patients with endometriomas. Fertil Steril 2004;82:1633-1637.
Beretta P, Franchi M, Ghezzi F, Busacca M, et al. Randomized clinical trial of two laparoscopic treatments of endometriomas: cystectomy versus drainage and coagulation. Fertil Steril 1998;70:1176-1180.
Dan H, Limin F. Laparoscopic ovarian cystectomy versus fenestration/coagulation or laser vaporization for the treatment of endometriomas: a meta-analysis of randomized controlled trials. Gynecol Obstet Invest 2013;76:75-82. doi: 10.1159/000351165. Epub 2013 Jun 6.
Moscarini M, Milazzo GN, Assorgi C, Pacchiarotti A, Caserta D. Ovarian stripping versus cystectomy: recurrence of endometriosis and pregnancy rate. Arch Gynecol Obstet 2014;290:163-167. doi: 10.1007/s00404-014-3158-z. Epub 2014 Feb 1.
Pellicano M, Bramante S, Guida M, Bifulco G, et al. Ovarian endometrioma: postoperative adhesions following bipolar coagulation and suture. Fertil Steril 2008;89:796-799. Epub 2007 Oct 22.
Matsuzaki S, Houlle C, Darcha C, Pouly JL, et al. Analysis of risk factors for the removal of normal ovarian tissue during laparoscopic cystectomy for ovarian endometriosis. Hum Reprod 2009;24:1402-1406. doi: 10.1093/humrep/dep043. Epub 2009 Feb 26.
Coccia ME, Rizzello F, Mariani G, Bulletti C, et al. Ovarian surgery for bilateral endometriomas influences age at menopause. Hum Reprod 2011;26:3000-3007. doi: 10.1093/humrep/der286. Epub 2011 Aug 24.
Reich H, Abrao MS. Post-surgical ovarian failure after laparoscopic excision of bilateral endometriomas: is this rare problem preventable? Am J Obstet Gynecol 2006;195:339-340. Epub 2006 May 24.
Celik HG, Dogan E, Okyay E, Ulukus C, et al. Effect of laparoscopic excision of endometriomas on ovarian reserve: serial changes in the serum antimüllerian hormone levels. Fertil Steril 2012;97:1472-1478. doi: 10.1016/j.fertnstert. 2012.03.027. Epub 2012 Apr 21.
Almog B, Shehata F, Sheizaf B, Tan SL, Tulandi T. Effects of ovarian endometrioma on the number of oocytes retrieved for in vitro fertilization. Fertil Steril 2011;95:525-527. doi: 10.1016/j.fertnstert.2010.03.011. Epub 2010 Apr 7.
Loo TC, Lin MY, Chen SH, Chung MT, et al. Endometrioma undergoing laparoscopic ovarian cystectomy: its influence on the outcome of in vitro fertilization and embryo transfer (IVF-ET). J Assist Reprod Genet 2005;22:329-333.
Ho HY, Lee RK, Hwu YM, Lin MH, et al. Poor response of ovaries with endometrioma previously treated with cystectomy to controlled ovarian hyperstimulation. J Assist Reprod Genet 2002;19:507-511.
Somigliana E, Ragni G, Benedetti F, Borroni R, et al. Does laparoscopic excision of endometriotic ovarian cysts significantly affect ovarian reserve? Insights from IVF cycles. Hum Reprod 2003;18:2450-2453.
Uncu G, Kasapoglu I, Ozerkan K, Seyhan A, et al. Prospective assessment of the impact of endometriomas and their removal on ovarian reserve and determinants of the rate of decline in ovarian reserve. Hum Reprod 2013;28:2140-2145. doi: 10.1093/humrep/det123. Epub 2013 Apr 26.
Hart RJ, Hickey M, Maouris P, Buckett W. Excisional surgery versus ablative surgery for ovarian endometriomata. Cochrane Database Syst Rev. 2008;16:CD004992. doi: 10.1002/14651858.CD004992.pub3. Review.
Dunselman GA, Vermeulen N, Becker C, Calhaz-Jorge C, et al; European Society of Human Reproduction and Embryology. ESHRE guideline: management of women with endometriosis. Hum Reprod 2014;29:400-412. doi: 10.1093/humrep/det457. Epub 2014 Jan 15.