Ortega-Rodés P, Grimm B, Ortega E

Idioma: Ingles.
Referencias bibliográficas: 105
Paginas: 176-186
Archivo PDF: 407.05 Kb.

RESUMEN

El grupo hemo, cofactor para proteínas esenciales, es sintetizado a partir de la inserción de Fe²+ en el anillo de protoporfirina por la enzima ferroquelatasa (FC). A pesar de que FC está bien caracterizada, existen aún incógnitas principales acerca de la regulación de la vía biosintética y la localización de la enzima en las plantas. Este artículo provee una revisión detallada acerca de las investigaciones sobre la función y el metabolismo del hemo en las plantas; incluye además información sobre las características únicas del metabolismo del hemo. Resumimos los conocimientos sobre la expresión, mecanismos de reacción, localización y filogenia de la FC. Incrementar el contenido de hierro hemo en los alimentos de origen vegetal es un gran reto biotecnológico para mejorar la ingesta de hierro en la población; el hierro hemo es de 5-10 veces más absorbido que el hierro no hemo. En esta revisión nosotros sugerimos modificaciones biotecnológicas potenciales en el metabolismo del hemo en las plantas para incrementar la capacidad de los cultivos de resistir los estreses biótico y abiótico y mejorar las cualidades nutricionales de las plantas como fuente de hierro para la dieta.

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