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2015, Número 1

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Rev Cubana Hematol Inmunol Hemoter 2015; 31 (1)


Propiedades inmunomoduladoras de las células madre mesenquimales

Miranda RA, Galván CJA, de León DJ

Idioma: Español
Referencias bibliográficas: 40
Paginas: 20-31
Archivo PDF: 248.92 Kb.


RESUMEN

Las estrategias de terapia celular se han utilizado con fines tan diversos como la regeneración de tejidos, la potenciación de la respuesta inmune antígeno específicas para la terapia antitumoral, la liberación de drogas en tejidos dañados y la restauración de la homeostasis en sitios con procesos inflamatorios crónicos. Dentro de las poblaciones celulares con mayor potencial para este tipo de alternativa terapéutica se incluyen las células madre mesenquimales (CMM), un grupo heterogéneo de células estromales multipotentes que se caracterizan por su baja inmunogenicidad y que ha demostrado una elevada versatilidad respecto a sus efectos inmunomoduladores. El presente trabajo recoge evidencias que se han acumulado en la última década que permiten valorar el potencial de las CMM para la terapia celular.


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