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2003, Número 1

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Med Cutan Iber Lat Am 2003; 31 (1)


Conceptos recientes en la inmunopatología cutánea

Robledo PMA, Díaz LA

Idioma: Español
Referencias bibliográficas: 126
Paginas: 3-16
Archivo PDF: 262.58 Kb.


RESUMEN

Esta revisión abarca la información científica más relevante sobre la inmunopatología de las enfermedades autoinmunes ampollosas, el liquen rubber plano y lupus. La inmunofluorescencia fue la primera herramienta usada como ayuda diagnóstica y a veces, pronóstica en las enfermedades autoinmunes cutáneas y aun continua siendo de gran ayuda para los clínicos. Al emplear antígenos recombinantes y adaptar técnicas de tipo ensayo inmunoenzimatico (ELISA), de inmunoprecipitación y de “immunoblotting” se aclaró la clasificación de estas enfermedades autoinmunes. Con ELISA se hacen diaria y simultáneamente diagnósticos en gran número de muestras, siendo los resultados rápidos, precisos y cuantitativos. Los recientes conocimientos en pénfigo como son las interacciones en la comunicación de los linfocitos T y B, además del reconocimiento de los epítopes de las desmogleinas, han dado base para


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