2014, Número 1
Factores asociados a la prehipertensión arterial en jóvenes de 20 a 25 años de edad
Merino BSI, Pérez FGA, Garí LM, González FV, González CB, Moreno-Martínez FL, Flores MJJ
Idioma: Español
Referencias bibliográficas: 55
Paginas: 25-35
Archivo PDF: 506.44 Kb.
RESUMEN
Introducción: La hipertensión arterial constituye un importante problema de salud a nivel mundial. La prehipertensión es una categoría que se ha estudiado poco en los jóvenes.
Objetivo: Determinar los factores asociados a la prehipertensión arterial en jóvenes entre 20 a 25 años de edad.
Método: Se realizó un estudio descriptivo y transversal a un universo constituido por 257 estudiantes de segundo año de medicina. Por muestreo aleatorio simple se escogieron 134 jóvenes entre 20 a 25 años de edad, correspondientes al curso académico 2009-2010.
Resultados: Se observó una prevalencia de prehipertensión arterial de 27,6 %. Los del sexo masculino (51,5 %) y de color de piel blanca (59,7 %) fueron los más afectados. El ambiente familiar, el antecedente personal de bajo peso al nacer (OR=2,3; p=0.179) y la edad gestacional menor de 37 semanas (OR=2,5; p=0.187) no influyeron en la posibilidad de presentar cifras prehipertensivas en los jóvenes de esta muestra.
Conclusiones: El índice de masa corporal elevado (OR=34,1; p‹0.001), los antecedentes familiares de hipertensión arterial (OR=12; p‹0.01) y la obesidad familiar (χ
2= 11,19; p=0.001), fueron los factores más fuertemente asociados a la prehipertensión arterial en estos jóvenes.
REFERENCIAS (EN ESTE ARTÍCULO)
World Health Organization. Global status report on noncommunicable diseases 2010. Geneva: World Health Organization, 2011.
Alwan A, Maclean DR, Riley LM, d'Espaignet ET, Mathers CD, Stevens GA, et al. Monitoring and sur-veillance of chronic noncommunicable diseases: progress and capacity in high-burden countries. Lancet. 2010;376(9755):1861-8.
Kaplan NM, Opie LH. Controversies in hyperten-sion. Lancet. 2006;367(9505):168-76.
Danaei G, Finucane MM, Lin JK, Singh GM, Paciorek CJ, Cowan MJ, et al. National, regional, and global trends in systolic blood pressure since 1980: sys-tematic analysis of health examination surveys and epidemiological studies with 786 country-years and 5·4 million participants. Lancet. 2011; 377(9765): 568-77.
Ostchega Y, Yoon SS, Hughes J, Louis T. Hyperten-sion awareness, treatment, and control – conti-nued disparities in adults: United States, 2005-2006. NCHS Data Brief. 2008;(3):1-8.
Ogihara T, Kikuchi K, Matsuoka H, Fujita T, Higaki J, Horiuchi M, et al. The Japanese Society of Hyper-tension Guidelines for the Management of Hyper-tension (JSH 2009). Hypertens Res. 2009;32(1):3-107.
Gabriel R, Alonso M, Segura A, Tormo MJ, Artigao LM, Banegas JR, et al. Prevalencia, distribución y variabilidad geográfica de los principales factores de riesgo cardiovascular en España. Análisis agru-pado de datos individuales de estudios epidemioló-gicos poblacionales: estudio ERICE. Rev Esp Cardiol. 2008;61(10):1030-40.
Alfonzo JP, Pérez MD, Hernández MJ, García D. Hipertensión arterial en la atención primaria de salud. La Habana: Editorial Ciencias Médicas; 2009.
Ministerio de Salud Pública. Anuario estadístico de salud 2011. La Habana: MINSAP; 2011.
10.Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL, et al. Seventh Report of the Joint National Committee on Prevention, Detection, Eva-luation, and Treatment of High Blood Pressure. Hypertension. 2003;42(6):1206-52.
11.Zhang Y, Lee ET, Devereux RB, Yeh J, Best LG, Fab-sitz RR, et al. Prehypertension, Diabetes, and Car-diovascular Disease Risk in a Population-Based Sample: the Strong Heart Study. Hypertension. 2006;47(3):410-4.
12.Ganguly SS, Al-Shafaee MA, Bhargava K, Duttagupta KK. Prevalence of prehypertension and associated cardiovascular risk profiles among prediabetic Omani adults. BMC Public Health [Internet]. 2008 [citado 2012 May 10];8(108):[aprox. 7 p.] Avail-able at: http://www.biomedcentral.com/1471-2458/8/108
13.Sipahi I, Tuzcu EM, Schoenhagen P, Wolski KE,
Nicholls SJ, Balog C, et al. Effects of normal, pre-hypertensive, and hypertensive blood pressure le-vels on progression of coronary atherosclerosis. J Am Coll Cardiol. 2006;48(4):833-8.
14.Ishikawa Y, Ishikawa J, Ishikawa S, Kayaba K, Naka-mura Y, Shimada K, et al: Prevalence and deter-minants of prehypertension in a Japanese general population: the Jichi Medical School Cohort Study. Hypertens Res. 2008;31(7):1323-30.
15.Tsai PS, Ke TL, Huang CJ, Tsai JC, Chen PL, Wang SY, et al. Prevalence and determinants of prehyperten-sion status in the Taiwanese general population. J Hypertens. 2005;23(7):1355-60.
16.Choi KM, Park HS, Han JH, Lee JS, Lee J, Ryu OH, et al. Prevalence of prehypertension and hyper-tension in a Korean population: Korean National Health and Nutrition Survey 2001. J Hypertens. 2006;24(8):1515-21.
17.Liszka HA, Mainous AG, King DE, Everett CJ, Egan BM. Prehypertension and cardiovascular morbidity. Ann Fam Med. 2005;3(4):294-9.
18.Vasan R, Larson M, Leip E, Kannel W, Levy D. Assessment of frequency of progression to hyper-tension in non-hypertensive participants in the Fra-mingham Heart Study: a cohort study. Lancet. 2001;358(9294):1682-6.
19.Grotto I, Grossman E, Huerta M, Sharabi Y. Pre-valence of prehypertension and associated cardio-vascular risk profiles among young Israeli adults. Hypertension. 2006;48(2):254-9.
20.Ferguson TS, Younger NO, Tulloch-Reid MK, Wright MB, Ward EM, Ashley DE, et al. Prevalence of prehypertension and its relationship to risk factors for cardiovascular disease in Jamaica: Analysis from a cross-sectional survey. BMC Cardiovasc Disord [Internet]. 2008 [citado 2012 May 19];8:20. Avail-able at: http://www.biomedcentral.com/1471-2261/8/20
21.Toprak A, Wang H, Chen W, Paul T, Ruan L, Sriniva-san S, et al. Prehypertension and black-white con-trasts in cardiovascular risk in young adults: Boga-lusa Heart Study. J Hypertens. 2009;27(2):243-50.
22.Bhatt DL, Steg PG, Ohman EM, Hirsch AT, Ikeda Y, Mas JL, et al. International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis. JAMA. 2006; 295(2):180-9.
23.Ridker PM, Buring JE, Rifai N, Cook NR. Develop-ment and validation of improved algorithms for the assessment of global cardiovascular risk in women: The Reynolds Risk Score. JAMA.2007;297(6):611-9.
24.Li L, Law C, Power C. Body mass index throughout the life-course and blood pressure in mid-adult life: a birth cohort study. J Hypertens. 2007;25(6):1215-23.
25.Figueroa-López C, Alcocer L, Ramos B. Factores de riesgo psicosociales asociados a los trastornos car-diovasculares en estudiantes universitarios. Anales de Psicología. 2011;27(3):739-44.
26.Clays E, Leynen F, De Bacquer D, Kornitzer M, Kittel F, Karasek R, et al. High job strain and ambulatory blood pressure in middle-aged men and women from the Belgian Job stress study. J Occup Environ Med. 2007;49(4):360-7.
27.Álvarez DM, Benavides JL, Bueno O, Cuadros VP, Echeverri DR, Gómez L, et al. Estudio comparativo del nivel de ansiedad, personalidad tipo A y facto-res de riesgo asociados a hipertensión arterial en pacientes hipertensos y no hipertensos. Archivos de Medicina (Col). 2006;13:51-67.
28.Flaa A, Eide IK, Kjeldsen SE, Rostrup M. Sympatho-adrenal stress reactivity is a predictor of future blood pressure: an 18-year follow-up study. Hyper-tension. 2008;52(2):336-41.
29.Grant C, Hobkirk A, Persons E, Hwang V, Danoff-Burg S. Cardiovascular reactivity to and recovery from stressful tasks following a mindfulness analog in college students with a family history of hyper-tension. J Altern Complement Med. 2013;19(4): 341-6.
30.Hwu C, Liou T, Hsiao C, Lin M. Prehypertension is associated with insulin resistance. Q J Med. 2009; 102(10):705-11.
31.Paulista MR, Stritzke J, Siewert U, Lieb W, Luchner A, Döring A, et al. Variation in Body Composition Determines Long-Term Blood Pressure Changes in Pre-Hypertension. The MONICA/KORA Cohort Stu-dy. J Am Coll Cardiol. 2010;56(1):65-76.
32.Zugasti A, Moreno B. Obesidad como factor de ries-go cardiovascular. Hipertensión. 2005;22(1):32-6.
33.Tirosh A, Afek A, Rudich A, Percik R, Gordon B, Aya-lon N, et al. Progression of normotensive adoles-cents to hypertensive adults. A study of 26980 teen- agers. Hypertension. 2010;56(2):203-9.
34.Silva DA, Petroski EL, Peres MA. Prehypertension and hypertension among adults in a metropolitan area in Southern Brazil: population-based study. Rev Saude Publica. 2012;46(6):988-98.
35.Barker DJ, Winter PD, Osmond C, Margetts B, Sim-monds SJ. Weight in infancy and death from is-chemic heart disease. Lancet. 1989;2(8663):577-80.
36.Gamborg M, Byberg L, Rasmussen F, Andersen PK, Baker JL, Bengtsson C, et al. Birth weight and sys-tolic blood pressure in adolescence and adulthood: meta-regression analysis of sex- and age-specific results from 20 Nordic studies. Am J Epidemiol. 2007;166(6):634-45.
37.Chen W, Srinivasan SR, Berenson GS. Amplification of the association between birth weight and blood pressure with age: the Bogalusa Heart Study. J Hypertens. 2010;28(10):2046-52.
38.Davies AA, Smith GD, May MT, Ben-Shlomo Y. Association between birth weight and blood press-ure is robust, amplifies with age, and may be under- estimated. Hypertension. 2006;48(3):431-6.
39.Feldt K, Räikkönen K, Eriksson JG, Andersson S, Os-mond C, Barker DJ, et al. Cardiovascular reactivity to psychological stressors in late adulthood is pre-dicted by gestational age at birth. J Hum Hypertens. 2007;21(5):401-10.
40.Hoy WE, Hughson MD, Singh GR, Douglas-Denton R, Bertram JF. Reduced nephron number and glo-merulomegaly in Australian Aborigines: A group at high risk for renal disease and hypertension. Kidney Int. 2006;70(1):104-10.
41.Tian JY, Cheng Q, Song XM, Li G , Jiang GX, Gu YY, et al. Birth weight and risk of type 2 diabetes, ab-dominal obesity and hypertension among Chinese adults. Eur J Endocrinol. 2006;155(4):601-7.
42.Keijzer-Veen MG, Finken MJ, Nauta J, Dekker FW, Hille ET, Frölich M, et al. Is blood pressure in-creased 19 years after intrauterine growth res-triction and preterm birth? A prospective follow-up study in The Netherlands. Pediatrics. 2005;116(3): 725-31.
43.Zhang M, Ardlie K, Wacholder S, Welch R, Chanock S, O'Brien TR. Genetic variations in CC chemokine receptors and hypertension. Am J Hypertens. 2006; 19(1):67-72.
44.Delles C, McBride MW, Graham D, Padmanabhan S, Dominiczak AF. Genetics of hypertension: From experimental animals to humans. Biochim Biophys Acta. 2010;1802 (12):1299-308.
45.Xie G, Guo D, Li Y, Liang S, Wu Y. The impact of severity of hypertension on association of PGC-1alpha gene with blood pressure and risk of hyper-tension. BMC Cardiovasc Disord [Internet]. 2007 citado 2012 May 22];7:33. Available at:
http://www.biomedcentral.com/1471-2261/7/33
46.Hottenga JJ, Whitfield JB, de Geus EJ, Booms DI, Martin NG. Heritability and stability of resting blood pressure in Australia twins. Twin Res Hum Genet. 2006;9(2):205-9.
47.del Rio Y, Castillo D, Mayo RC. Contribución de los factores genéticos y ambientales en el desarrollo de la hipertensión arterial en estudios de gemelos en el municipio Chambas. Mediciego [Internet]. 2011 [citado 2012 May 10];17(1):[aprox. 9 p.] Avail-able at:
http://bvs.sld.cu/revistas/mciego/Vol17_01_%202011/articulos/t-10.html
48.Pérez GA. Estrés e hipertensión arterial. Resultados del proyecto “Hacia un pesquisaje en la adolescen-
cia de HTA (PESESCAD-HTA)”. Med Gen. 2002;41: 99-104.
49.Steyn NP, Nel JH, Parker WA, Ayah R, Mbithe D. Dietary, social, and environmental determinants of obesity in Kenyan women. Scand J Public Health. 2011;39(1):88-97.
50.Richardson LJ, Hussey JM, Strutz KL. Origins of disparities in cardiovascular disease: Birth weight, body mass index, and young adult systolic blood pressure in the National Longitudinal Study of Adolescent Health. Ann Epidemiol. 2011;21(8):598-607.
51.Esler M, Straznicky N, Eikelis N, Masuo K, Lambert G, Lambert E. Mechanisms of sympathetic ac-tivation in obesity-related hypertension. Hyperten-sion. 2006;48(5):787-96.