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ISSN 0187-5337 (Impreso)
Instituto Nacional de Perinatología

2014, Número 4

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Perinatol Reprod Hum 2014; 28 (4)


Variations in the differential leukocyte count from birth through the first two months of age in term infants with low perinatal risk

Baptista-González HA, Rosenfeld-Mann F, Trueba-Gómez R, Coeto-Barona G, Bouchán-Valencia P

Idioma: Español
Referencias bibliográficas: 31
Paginas: 198-204
Archivo PDF: 303.20 Kb.


RESUMEN

Introducción: La presencia de neutropenia o neutrofilia se observa en la evaluación del neonato con sospecha de sepsis; sin embargo, en ausencia de infección sistémica, su incidencia no ha sido estimada en nuestra población. Material y métodos: En una cohorte de recién nacidos a término de bajo riesgo perinatal, seguidos desde el nacimiento hasta los dos meses de edad; se evaluaron la cuenta de leucocitos, neutrófilos (NT), linfocitos totales (LT) y la frecuencia de neutropenia a estas edades. Resultados: Se incluyeron 110 recién nacidos de bajo riesgo perinatal, evaluados al nacer, al mes y a los dos meses de edad. Los leucocitos totales promedio fueron de 18,950/µL (IC 95% 10,255 a 29,170), 11,250/µL (6,030-17,045) y 9,750/µL (6,055-17,900); los linfocitos totales de 7,442/µL (4,736-11,326), 8,198/µL (2,625-12,559) y 7,478/µL (4,276-12,782); los neutrófilos totales de 7,818/µL (2,853-13,809), 2,112 (927-7,021) y 1,944 (737-3,618), respectivamente. La incidencia de neutropenia significativa (‹ 750/L) fue del 0.9 al nacimiento, 2.7 al mes y 5.5% a los dos meses de edad. La neutrofilia (› 9,500/L) se presentó en el 35.5% de los neonatos al nacimiento, pero en ningún caso hacia el resto de las edades de estudio. Conclusiones: La presencia de neutropenia o neutrofilia es un cambio fisiológico en el neonato o lactante menor de bajo riesgo. Este hecho debe ser considerando en su interpretación particular en la evaluación de la sepsis a estas edades.


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