2014, Número 2
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Rev Cubana Invest Bioméd 2014; 33 (2)
Crecimiento pre y postnatal asociados a sobrepeso corporal en escolares de Bayamo
Suárez RM, Ruiz ÁV, Alegret RM, Díaz SME, Hernández TM
Idioma: Español
Referencias bibliográficas: 135
Paginas: 204-230
Archivo PDF: 238.33 Kb.
RESUMEN
Objetivo: identificar la asociación entre factores prenatales y relacionados con el primer año de vida y su influencia en el sobrepeso corporal de edades ulteriores.
Métodos: se realizó un estudio observacional, retrospectivo, analítico, de casos y controles en el municipio Bayamo con 200 escolares con sobrepeso corporal y 200 niños normales de 6-11 años de edad, de la misma zona de residencia, nacidos de madres con similar edad gestacional de 37-42 semanas, homogéneos en edad y sexo y con historia de no afecciones de salud. En el análisis estadístico se estimó el riesgo asociado como Odd Ratio.
Resultados: se mostró una fuerte asociación entre el sobrepeso corporal en la edad escolar y la ganancia de peso excesiva en los primeros 4 meses de vida, bajo peso, reducida longitud supina y circunferencia cefálica en el momento del nacimiento y hábito de fumar, insuficiente ganancia de peso corporal, bajo IMC y enfermedades de la madre durante el embarazo.
Conclusiones: estos factores deben ser considerados en la prevención de la obesidad infantil. La ganancia de peso acelerada en los primeros meses de vida de niños nacidos con afectación del crecimiento fetal debe ser prevenida.
REFERENCIAS (EN ESTE ARTÍCULO)
Kain J, Albala C, García F, Andrade M. Obesidad en el preescolar: evolución antropométrica y determinantes socioeconómicos. Rev. Med. Chile 1998;(126):271-8.
Mardones F, Bastías G, Farías M, Dinamarca Raúl, Olavarría F, Rada G, Rojas A, Rojas P. Composición corporal de neonatos con alteraciones en el crecimiento fetal. Rev. Chil. Pediatr.1999;(70):300-5.
Oken E, Gillman W. Fetal Origins of Obesity. Obesity Research 2003;(11):496-506
Soto N, Rodrigo A, Bazáes RA, Peña V, Salazar T, Avila A, Iñiguez G, Ong KK, Dunger DB, Mericq V. Insulin sensitivity and secretion are related to catch-up growth in small-for-gesttionalage infants at one year: results from a prospective cohort. J Clin. Endocrinol. Metab 2003;(88):3645-50.
Violante R, del Rio Navarro BE, Berber A, Ramirez Chanona N, Baeza Bacab M, Sienra Monge JJ. Obesity risk factors in the ISAAC (International Study of Asthma and Allergies in Childhood) in Mexico City. Rev. Alerg. Mex 2005;(52):141-5.
Mericq V, Ong KK, Peña V, Avila A, Salazar T, Soto N, [et.al]. Longitudinal changes in insulin sensitivity and secretion from birth to age three years in small- and appropriate-forgestational-age children. Diabetologia 2005;(48):2609-14.
Raghav CH. Risk factors for death in infancy persist into older age groups in England and Wales. BMJ 2004;(329):1204-6.
Rogers and the EURO-BLCS Study Group. The influence of birthweight and intrauterine environment on adiposity and fat distribution in later life. Int J Obes 2003;(27):755-77.
Ekelund U, Ong K, Linné Y, Neovius M, Brage S, Dunger D, [et.al]. Upward weight percentile crossing in infancy and early childhood independently predicts fat mass in young adults: the Stockholm Weight Development Study (SWEDES). Am J Clin Nutr 2006;(83):324-30.
Remacle C, Bieswal F, Rouses B. Programming of obesity and cardiovascular disease. Int. J Obes 2004;(28):S46-S53.
Schroeder D, Martorell R, Flores R. Infant and Child Growth and Fatness and Fat Distribution in Guatemala. Am. J Epidemiol 1999;(149):177-85.
Harder T, Rodekamp E, Schellong K, Dudenhausen J, Plagemann A. Birth Weight and Subsequent Risk of Tipe 2 Diabetes: A Meta-Analysis. Am. J Epidemiol 2007;(165):849-57.
Murtaugh M, Jacobs D, Moran A, Steinberger J, Sinaiko A. Relation of Birth Weight to Fasting Insulin, Insulin Resistance, and Body Size in Adolescence. Diabetes Care 2003;(26):187-92.
Kain J, Lera L, Rojas J, Uauy R. Obesidad en preescolares de la Región Metropolitana de Chile. Rev. Med. Chile 2007;(135):63-70.
Loaiza S, Atalah E. Peso de nacimiento como factor de riesgo de obesidad en escolares de primer año medio. [Tesis para optar al grado de Doctor en Salud Pública]. Escuela de Salud Pública, Universidad de Chile, 2008.
Loaiza S, Atalah E. Factores de riesgo de obesidad en escolares de primer año básico de Punta Arenas. Rev. Chil. Pediatr. [en línea]. 2006;77(1): Disponible en: http://www.scielo.cl/scielo.php?cript=sci_arttext&pid=S0370-41062006000100003&lng=es. doi: 10.4067/S0370-41062006000100003. [Consultado: 29/9/2009].
MCmillenI C, Robinson JS. Developmental origins of the metabolic syndrome: prediction, plasticity, and programming. Physiol. Rev 2005; 85:571-633.
Gluckman PD, Hanson MA. Developmental Origins of Disease Paradigm: A Mechanistic and Evolutionary Perspective Pediatric. Research 2004;56:311-17.
Krishnaveni GV, Hill JC, Veena SR, Leary SD, SaperiaJ, Chachyamma KJ, [et al]. Truncal adiposity is present al birth and in early childhood in South Indian children. Indian Pediatr 2005;42(6):527-38.
Fernández P. Asociación de bajo peso al nacer con Diabetes y Obesidad en la adultes. El Litoral [en línea]. 2007. Disponible en: http://www.ellitoral.com/index.php/diarios/2007/11/21/udopina/index.htnl [Consultado: 7/5/2009].
Hales CN, Ozanne DE. The dangerous road of catch-up growth. J. Physiol 2003;547:5-10.
Cormillo T. El Origen fetal de la Obesidad. Dr Comillot. [en línea]. 2008. Disponible en: http://www.drcormillot.com/clinica_nutricion/default.php [Consultado: 7/5/2008].
Barker DJP. Fetal origins of coronary heart disease. BMJ 1995;311(15):171-174.
Barker DJP. Early growth and cardiovascular disease. Arch. Dis. Child 1999; 837:305-307.
Schwartz J, Morrison JL. Impact and mechanisms of fetal physiological programming. Am J Physiol Regulatory Integrative Comp Physiol 2005;288:11-15.
McMillen IC, Edwards LJ, Duffield J, Muhlhausler BS. Regulation of leptin synthesis and secretion before birth: implications for the early programming of adult obesity. Reproduction 2006;131:415-427.
Jiménez-Chillaron JC, Patti ME. To catch up or not to catch up: is this the question? Lessons from animal models. Curr. Opin. Endocrinol. Diabetes. Obes 2007;14:23-29.
Adair LS, Prentice AM. A critical evaluation of the fetal origins hypothesis and its implications for developing countries. J Nutr 2004;(134):191-3.
Caballero B. The Global Epidemic of Obesity: An Overview. Epidemiol Rev 2007;(29):1-5.
Eriksonn JG. The fetal origins hypothesis-10 years on. BMJ 2005;(330):1096-7.
Caballero B. A nutrition paradox - underweight and obesity in developing countries. N Eng J Med 2005;(352):1514-6.
Olivares S, Kain J, Lera L, Pizarro F, Vio F, Morón C. Nutritional status, food consumption and physical activity among Chilean school children: a descriptive study. Eur J Clin Nutr 2004;(58):1278-85.
Ariza J. Consenso de la Federación Latinoamericana de Sociedades de Obesidad (FLASO). 1998:7-22.
Buchan IE, Heller RF, Clayton P, Bundred PE, Cole TJ. Early life risk factors for obesity in childhood: early feeding is crucial target for preventing obesity in children. BMJ 2005;331(7514):453-4.
Reilly JJ. Early life risk factors for obesity in childhood: cohort study. BMJ. 2005;330(7504):1357.
von Kries R, Toschke AM, Koletzko B. Maternal smoking during pregnancy and childhood obesity. Am J Epidemiol 2002;156:954-61.
Troiano RP, Flegal KM. Overweight children and adolescents: description, epidemiology, and demographies. Pediatrics 1998;101:497-504.
Rasmussen F, Johansson M. The relation of weight, length and ponderal index at birth to body mass index and overweight among 18-year-old males in Sweden. Eur J Epidemiol 1998;14:373-80.
Locard E, Mamelle N, Billette A, et al. Risk factors of obesity in a five year old population. Parental versus environmental factors. Int Obes Relat Metab Disord 1992;16:721-9.
Robinson TN. Reducing children's television viewing to prevent obesity: a randomized controlled trial. JAMA 1999;282:1561-7.
Moore LL, Nguyen US, Rothman KJ, et al. Preschool physical activity level and change in body fatness in young children. The Framingham Children's Study. Am J Epidemiol 1995;142:982-8.
Toschke AM, Vignerova J, Lhotska L, et al. Overweight and obesity in 6 to 14 year-old Czech children in 1991: protective effect of breast-feeding. J Pediatr 2002;141:764-9.
Kuczmarski RJ, Ogden CL, Guo SS, et al. 2000 CDC growth charts for the United States: methods and development. Vital Health Stat 11. 2002;11(246):1-190.
Weiner JS, Lourie JA. Human Biology. A guide to field methods. Oxford: Blackwell Scientific Publications;1969. (Handbook No. 9).
Chumlea WC. Methods of Nutritional Anthropometric assessment for special groups. In: Lohman TG, Roche AF, Martorell R, editors. Anthropometric Standardization Reference Manual. Illinois: Human Kinetics Books.1988;pp:93-5.
Institute of Medicine. Nutrition during pregnancy, weight gain and nutrient supplements. Reports of the Subcommittee on Nutritional Status and Weight Gain during Pregnancy, Subcommittee on Dietary Intake and Nutrient Supplements during Pregnancy and Lactation, Food and Nutrition Board. Washington, DC: National Academy Press, 1990:1-233.
Ramírez E, Grijalva-Haro MI, Ponce JA, Valencia ME. Prevalencia de sobrepeso y obesidad en el noroeste de México por tres referencias de índice de masa corporal: diferencias en la clasificación. ALAN [serie en Internet]. 2006; 56 (3): [aprox. 3 p.]. Disponible en: http://www.alanrevista.org/ediciones/2006-3/htm. [Consultado: 25/7/2009].
He M, Beynon C. Prevalence of overweight and obesity in school-aged children. Can J Diet Pract. Res 2006;67(3):125-9.
Victoria I, Dalmau J. Prevalencia de la obesidad en la infancia y la adolescencia. Actividad desde la atención primaria. Nutr Clin 2004;41(2):35-44.
Oken E, Gillman MW. Fetal Origins of Obesity. Obesity Research 2003; 11:496-506.
Hulman S, Kushner H, Katz S, Falkner B. Can cardiovascular risk be predicted by newborn, childhood, and adolescent body size? An examination of longitudinal data in urban African Americans. J Pediatr 1998;132: 90-7
Curhan GC, Chertow GM, Willett WC, Spiegelman D, Colditz GA, Manson JE, [et al]. Birth weight and adult hypertension and obesity in women. Circulation 1996;94:1310-5
Okosun, IS, Liao, Y, Rotimi, CN, Dever, GE, Cooper, RS. Impact of birth weight on ethnic variations in subcutaneous and central adiposity in American children aged 5-11 years Int J Obes Relat Metab Disord 2002; 24:479-84.
Barker M, Robinson S, Osmond C, Barker DJ. Birth weight and body fat distribution in adolescent girls. Arch. Dis. Child 1997;77:381-3.
Walker SP, Gaskin PS, Powell CA, Bennett FI. The effects of birth weight and postnatal linear growth retardation on body mass index, fatness and fat distribution in mid and late childhood. Public Health Nutr 2002;5(3):391-6.
Phylips W. Childhood Obesity. Consensus Statement. J Clin. Endocrinol. Metab 2005; 90(3):1871-87.
Amador García M, Cobas Selva M, Hermelo Treche M. Evaluación del estado de nutrición. En: Torre Montejo E de la, [et.al]. Pediatría. T: 2. La Habana: Ed. Pueblo y Educación 1996. p:75-86
Cabrera Hernández A, Damiani Roseli A, Chiong Molina D, Quintero Alejo ME, Fernández Ubeda L. Relación entre los lípidos séricos y la distribución de grasa corporal en un grupo de niños obesos. Rev. Cub. Aliment. Nutr. [en línea]. 1996;10(2): Disponible en: http://bvs.sld.cu/revistas/ali/vol10_2_96/ali10296.htm. [Consultado: 25/7/2009].
Esquivel V, Suárez de Ronderos P, Calzada L, Sandí L, Ureña J. Factores de Riesgo Cardiovascular en un grupo de niños escolares obesos Costarricenses. Acta Pediátr. Costa Rica 2002;16(1):15-8.
Castellón Pérez M. Correlación clínica de obesidad y alteración de pruebas bioquímicas. [Tesis]. Managua, Nicaragua: Universidad Nacional Autónoma de Nicaragua;2005.
Pajuela J, Cancharf E, Carrera J, Leguía D. La circunferencia de la cintura en niños con sobrepeso y obesidad. An Fac Med Lima 2004;65(3):167-71.
Ong KK. Size at birth, postnatal growth and risk of obesity. Horm Res. 2006;65(Suppl 3):65-9.
Sallout B, Walker M. The fetal origin of adult diseases. J Obstet. Gynaecol. 2003;23:555-60.
Barker DJ. Intrauterine programming of adult disease. Mol Med Today. 1995;1:418-23.
Barker DJP. Mothers, Babies and Health in Later Life. Edinburgh, Scotland: Churchill Livingston; 1998.
Hales CN, Barker DJP. The thrifty phenotype hypothesis. Br Med Bull 2001; 60:5-20.
Ravelli A, Vander Meulen J, Osmond C, Barker D, Bleker O. Obesity at the age of 50 in men and women exposed to famine prenatally. Am J Clin Nut 1999;70:811-6.
Roseboom T, Vander Meulen J, Osmond C, Barker D, Ravelli A, Schroeder-Tanka J, et al. Coronary heart disease after prenatal exposure to the Dutch famine, 1944-45. Hear 2000;84:595-8.
Roseboom T, Vander Meulen J, van Montfrans G, Ravelli A, Osmond C, Barker D, [et al]. Maternal nutrition during gestation and blood pressure in later life. J Hypertens. 2001;19:29-34
Godfrey KM, Barker DJ. Fetal nutrition and adult disease. Am J Clin Nutr 2000;71:1344-52.
Barker DJ. In utero programming of chronic disease. Clin Sci (Colch) 1998;95:115-28.
Yajnik CS, Fall CH, Coyaji KJ, Hirve SS, Rao S, Barker DJ, [et al]. Neonatal anthropometry: the thin-fat Indian baby. The Pune Maternal Nutrition Study. Int J Obes Relat Metab Disord. 2003;27:173-80.
Yajnik CS. The lifecycle effects of nutrition and body size on adult adiposity, diabetes and cardiovascular disease. Obesity Rev 2002;3:217-24.
Yajnik CS. Early life origins of insulin resistance and type 2 diabetes in India and other Asian countries. J Nutr 2004;134:205-10.
Yajnik CS, Lubree HG, Rege SS, Naik SS, Deshpande JA, Deshpande SS, [et al]. Adiposity and hyperinsulinemia in Indians are present at birth. J Clin Endocrinol Metab 2002;87:5575-80.
Garnett SP. Abdominal fat and birth size in healthy prepubert children.Int J Obes Relat Metab Disord 2001;25(11):1667-73.
Holt RI. Fetal programming of the growth hormone-insulin-like growth factor axis. Trends Endocrinol Metab 2002;13:392-7.
Cutfield WS, Hofman PL, Vickers M, Breier B, Blum WF, Robinson EM. IGFs and binding proteins in short children with intrauterine growth retardation. J Clin Endocrinol Metab 2002;87:235-9.
Meyre D. Is Glutamate Decarboxylase 2 (GAD2) a Genetic Link between Low Birth Weight and Subsequent Development of Obesity in Children? J Clin Endocrinol Metab 2005;90(4):2384-90.
Moreno Villares JN, Dalmau Serra J. Alteraciones en la nutrición fetal y efectos a largo plazo.¿Algo más que una hipótesis? Acta Pediatr. Esp 2001;59:573-81.
Torres AM. Evaluación del estado nutricional en escolares de bajos recursos socioeconómicos en el contexto de la transición nutricional. Arch. Argent. Pediatr. [en línea]. 2005;103(3):205-211. Disponible en: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0325-00752005000300004&lng=es&nrm=iso. [Consultado: 14/11/2009].
Juarte ER; López Montero M; Trufero Cánovas N. Efectos del bajo peso materno preconsepcional sobre el embarazo y el parto. Policlínico Comunitario Docente "Carlos J. Finlay" Camagüey. Archivo Médico de Camagüey. [en línea]. 2006;10(4). Disponible en: http://www.amc.sld.cu/amc/2006/v10n4-2006/2113.pdf. [Consultado: 14/11/2009].
Woodall SM, Johnston BM, Breier BH, Gluckman PD. Chronic maternal undernutrition in the rat leads to delayed postnatal growth and elevated blood pressure of offspring. Pediatr. Res 1996;40:438-43.
Persson E, Jansson T. Low birth weight is associated with elevated adult blood pressure in the chronically catheterized guinea pig. Acta Physiol. Scand 1992;145:195-6.
Oliver MH, Gluckman PD, Breier BH, Harding JE. Brief Undernutrition of Sheep in Late Gestation Causes Insulin Resistance in the Adult Offspring. International Fetal Physiology Symposium, Aspen.1999; A 19.
Kwong WY, Wild AE, Roberts P, Willis AC, Fleming TP. Maternal undernutrition during the preimplantation period of rat development causes blastocyst abnormalities and programming of postnatal hypertension. Development 2000;127:4195-202.
MacLaughlin SM, Walter SK, Roberts CT, Kleemann DO, McMillen IC. Preconceptional nutrition and the relationship between maternal body weight changes in the periconceptional period and feto-placental growth in the sheep. J Physio 2005;565(1):111-24.
Gluckman PD. (Editorial). Nutrition, glucocorticoids, birth size, and adult disease. Endocrinology 2001;142:1689-91.
Krause B, Sobrevia L, Casanello P. Papel de la placenta en la programación fetal de las enfermedades crónicas del adulto. En: Uauy R, Camuerga E, Barrer D, [et.al]. [libro en Internet]. Impacto del crecimiento y del desarrollo temprano sobre la salud y bienestar de la población. Instituto Danone, Nov 2009. Disponible en: http://www.institutodanoneconosur.org. [Consultado: 4/11/2009].
Heijmans BT, Tobi EW, Stein AD, Putter H, Blauw GJ, Susser ES, [et.al]. Persistent epigenetic differences associated with prenatal exposure to famine in humans. ProcNatl Acad Sci USA 2008;(105):17046-9.
Carbillon L, Uzan M, Uzan S. Pregnancy, vascular tone, and maternal hemodynamics: acrucial adaptation. Obstet Gynecol Surv 2000;(55):574-81.
Saldeen P, Olofsson P, Laurini RN. Structural, functional and circulatory placental changes associated with impaired glucose metabolism. Eur J Obstet Gynecol Reprod Bio 2002;(105):136-42.
Casanello P, Escudero C, Sobrevia L. Equilibrative nucleoside (ENTS) and cationic amino acid (CATS) transporters: implications in foetal endothelial dysfunction in human pregnancy diseases. Curr Vasc Pharmacol 2007;(5):69-84.
Karadas B, Kaya T, Cetin M, Parlak A, Durmus N, Bagcivan I, Gulturk S. Effects of formoterol and BRL 37344 on human umbilical arteries in vitro in normotensive and pre-eclamptic pregnancy. Vascul Pharmacol 2007;(46):360-6.
Yura S, Fujii S. Obesity in offspring with undernutrition during pregnancy. Nippon Rinsho 2006; 64 (4):795-803.
Laitinen J, Power C, Jarvelin MR. Family social class, maternal body mass index, childhood body mass index, and age at menarche as predictors of adult obesity. Am J Clin Nutr 2001;74:287-94
Stettler N, Tershakovec AM, Zemel BS. Early risk factors for increased adiposity: a cohort study of African American subjects followed from birth to young adulthood. Am J Clin Nutr 2000;72:378-83.
Whitaker R. Predicting Preschooler Obesity at Birth: The Role of Maternal Obesity in Early Pregnancy. Pediatrics 2004;114(1):29-36.
157. Chagnon YC, Rankinen T, Snyder EE, Weisnagel SJ, Perusse L, Bouchard C. The human obesity gene map: the 2002 update. Obes Res 2003;11:313-67.
Valderrama F, Cabrera E, Herrera J. Estado nutricional pregestacional y ganancia de peso materno durante la gestación y su relación con el peso del recién nacido. Rev. Med. Hered 2003;14(3).
Jansson T, Powell TL. Role of the placenta in fetal programming: underlying mechanisms and potential interventional approaches. Clin Sci (Lond) 2007;(113):1-13.
Calderon IM, Damasceno DC, Amorin RL, Costa RA, Brasil MA, Rudge MV. Morphometric study of placental villi and vessels in women with mild hyperglycemia or gestational or overt diabetes. Diabetes Res Clin Pract2007;(78):65-71.
Roberts JM, Catov JM. Preeclampsia more than 1 disease: or is it? Hypertension. 2008;(51):989-90.
Álvarez Fumero R, Urra Cobas LR, Aliño Santiago M, Repercusión de los factores de riesgo en el bajo peso al nacer. RESUMED. [en línea]. 2001;14(3):115-21. Disponible en: http://www.bvs.sld.cu/revistas/res/vol14_3_01/res02301.pdf. [Consultado: 28/11/2005].
Power C, Jefferis BJ. Fetal environment and subsequent obesity: a study of maternal smoking. Int J Epidemiol 2002;31:413-19.
Toschke M, Koletzko B, Slikker W Jr. Childhood obesity is associated with maternal smoking in pregnancy. Eur J Pediatr 2002;161:445-8.
Von Kries R, Toschke AM, Koletzko B. Maternal smoking during pregnancy and childhood obesity. Am J Epidemiol 2002;156:954-61.
Al Mamun A, Lawlor DA, Alati R, O'Callaghan MJ, Williams GM, Najman JM. Does maternal smoking during pregnancy have a direct effect on future offspring obesity? Evidence from a prospective birth cohort study. Am J Epidemiol 2006;164(4):317-25.
Oken E, Huh SY, Taveras EM, Rich-Edwards JW, Gillman MW. Associations of Maternal Prenatal Smoking with Child Adiposity and Blood Pressure. Obesity Research 2005;13:2021-8.
Ong KK, Ahmed ML, Emmett PM, Preece MA, Dunger DB. Association between postnatal catch-up growth and obesity in childhood: prospective cohort study. BMJ 2000;320:967-71.
Stettler N, Zemel BS, Kumanyika S, Stallings VA. Infant weight gain and childhood overweight status in a multicenter, cohort study. Pediatrics 2002;109(2):194-9.
Stettler N, Kunanyika SK, Katz SH, Zemel BS, Stallings VA. Rapid weight gain during infancy and obesity in young adulthood in a cohort of African Americans. Am J Clin Nutr 2003;77(6):1374-8.
Macías Gelabert A, Hernández Triana M, Ariosa Abreu J, Alegret Rodríguez M. Crecimiento prenatal y crecimiento posnatal asociados a obesidad en escolares. Rev. Cub. Invest Bioméd. [ en línea]. 2007;26(3). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-l03002007000300002&lng=es. [Consultado: 28/11/2005].
Seidman DS, Laor A, Gale R, Stevenson DK, Danon YL. A longitudinal study of birth weight and being overweight in late adolescence. Am J Clin Nutr 1991;145:782-5.
Tanner JM. Growth from birth to two: a critical review. Acta Médica. Auxológica 1994;26:7-45.
Tanner JM, Healy MJR, Lockhart RD, Mac-Kenzie JD, Whitehouse RH. Aberdeen growth study I. The prediction of adult body measurements from measurements taken each year from birth to five years. Arch. Dis. Chile 1956;46:372-81.
Giuffré E. La Obesidad Infantil. ESMERALDA 183. [en línea]. Disponible en: http://www.monografias.com/trabajos14/obesidadinfan/obesidadinfan.shtml [arroba]arnet.com.ar. [Consultado: 28/11/2005].
Ivanovic R, Olivares M, Ivanovic D. Estado nutricional en escolares chilenos urbanos y rurales de la Región Metropolitana, 1986-1987. Rev. Chil. Pediatr 1990;61(4):210-7.
Ong KK, Dunger DB. Perinatal growth failure: the road to obesity, insulin-resistance and cardio-vascular disease in adults. Best Pract Res Clin Endocrinol Metab 2002;16:191-207.
Eriksson JG, Forsen T, Tuomilehto J, Jaddoe VW, Osmond C, Barker DJ. Effects of size at birth and childhood growth on the insulin resistance syndrome in elderly individuals. Diabetologia 2002;45:342-8.
Ounsted M, Sleigh G. The infant's self-regulation of food intake and weight gain. Difference in metabolic balance after growth constraint or acceleration in utero. Lancet 1975;1:1393-7.
Ong KK, Ahmed ML, Sherriff A, Woods KA, Watts A, Golding J, [et al]. Cord blood leptin is associated with size at birth and predicts infancy weight gain in humans. J Clin Endocrinol Metab 1999;84:1145-8.
Lewis DS, Bertrand HA, McMahan CA, McGill Jr, Carey KD, Masoro EJ. Reweaving food intake influences the adiposity of young adult baboons. J Clin Invest 1986;78:899-905
Faust IM, Johnson PR, Hirsch J. Long-term effects of early nutritional experience on the development of obesity in the rat. J Nutr 1980; 110:2027-34.
Wasteland RA, Gaza C. Early postnatal nutrition determines adult pancreatic glucose-responsive insulin secretion and islet gene expression in rats. J Nutr 2002;132:357-64.
Martorell R, Kettel Khan L, Schroeder DG. Reversibility of stunting: epidemiological findings in children from developing countries. Eur J Clin Nutr. 1994;(48):S45-S57.
Owen CG, Martin RM, Whincup PH, Davey Smith G, Cook DG. Effect of infant feeding on the risk of obesity across the life course: a quantitative review of published evidence. Pediatrics 2005;( 115):1367-77.
Michels KB, Willett WC, Graubard BI, Vaidya RL, Cantwell MM, Simsbury LB, Forman MR. A longitudinal study of infant feeding and obesity throughout life course Int J Obes . 2007;(31):1078-85.
Martin R, Ben-Shlomo Y, Gunnell D, Ellwood P, Yarnell J, Davey S, [et.al]. Estado nutricional en escolares chilenos urbanos y rurales de la Región Metropolitana, 1986-1987. Rev Chil Pediatr 1990;61(4):210-7.
Singhal A, Baroque IS O'Rahilly S, Cole TJ, Fewtrell M, Lucas A. Early nutrition and leptin concentrations in later life. Am J Clin Nutr 2002;(75):993-9.
Gillman MW, Rifas-Shiman SL, Camargo CA Jr, [et al]. Risk of overweight among adolescents who were breastfed as infants. JAMA 2001;258:2461-7.
Desai M, Gayle D, Babu J, Ross M. Programmed obesity in intrauterine growth-restricted newborns: modulation by newborn nutrition. Am J Physiol Regul Integr Comp Physiol 2005;288:91-6.
Sahu A. A hypothalamic role in energy balance with special emphasis on leptin. Endocrinology 2004;145:2613-20.
Pizarro QT. Intervención nutricional a través del ciclo vital para la prevención de obesidad y otras enfermedades crónicas no transmisibles Rev Chil Pediatr 2007;78(1):76-83.
Chueca M, Azcona C. Obesidad infantil .España [en Iínea]. 2009; 125 (Supl.1):1-20. Disponible en: http://www.cfnavarra.es/salud/anales/textos/vol125/sup1/suple13a.htm1. [Consultado: 28/11/2005].