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2014, Número 4

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Rev Cubana Hematol Inmunol Hemoter 2014; 30 (4)


Inmunosenescencia: efectos de la edad sobre el sistema inmune

Saavedra HD, García VB

Idioma: Español
Referencias bibliográficas: 58
Paginas: 332-345
Archivo PDF: 144.03 Kb.


RESUMEN

El proceso de envejecimiento provoca cambios en el sistema inmune que afectan su funcionamiento y desarrollo. Estos cambios pueden manifestarse desde la linfopoyesis hasta la respuesta que orquesta el sistema inmune frente a determinada enfermedad o agente infeccioso. Ambas ramas de la inmunidad, innata y adaptativa, se afectan en este proceso, lo que genera un impacto negativo en la respuesta inmune de los ancianos y los predispone a padecer enfermedades infecciosas, cáncer, autoinmunidad y a desarrollar respuestas pobres tras la administración de vacunas.


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