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2014, Número 2

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Rev Méd Electrón 2014; 36 (2)


La acción cardioprotectora del uso moderado de alcohol

Arredondo BA, del Risco MO

Idioma: Español
Referencias bibliográficas: 49
Paginas: 181-194
Archivo PDF: 102.29 Kb.


RESUMEN

Introducción: el objetivo de esta revisión fue enfocar el conocimiento de los beneficios cardiovasculares del consumo moderado de alcohol, así como para analizar los efectos de los diferentes tipos de bebidas alcohólicas.
Discusión: el consumo fuerte de alcohol indiscutiblemente lleva a una morbimortalidad aumentada, el consumo moderado del alcohol, especialmente las bebidas alcohólicas ricas en polifenoles, como el vino y cerveza, parece conferir efectos de protección cardiovascular en los pacientes portadores de esta enfermedad, e incluso en las personas saludables.
Conclusiones: en conclusiones, el vino y la cerveza (pero el vino especialmente tinto) parece conferir protección cardiovascular mayor que las espirituosas debido a su volumen de polifenoles. Sin embargo, la bebida debe tomarse con cautela y seguir las recomendaciones sociales relacionadas al consumo del alcohol.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. Mukamal KJ, Conigrave KM, Mittleman MA, Camargo CA Jr, Stampfer MJ, Willett WC, et al. Roles of drinking pattern and type of alcohol consumed in coronary heart disease in men. N Engl J Med. 2003;348:109-18. Citado en PubMed; PMID: 12519921.

  2. Brien SE, Ronksley PE, Turner BJ, Mukamal KJ, Ghali WA. Effect of alcohol consumption on biological markers associated with risk of coronary heart disease: systematic review and meta-analysis of interventional studies. Br Med J. 2011;342:636-46. Citado en PubMed; PMID: 21343206.

  3. Ronksley PE, Brien SE, Turner BJ, Mukamal KJ, Ghali WA. Association of alcohol consumption with selected cardiovascular disease outcomes: a systematic review and meta-analysis. Br Med J. 2011;342:671-81. Citado en PubMed; PMID: 21343207.

  4. Renaud S, de Lorgeril M. Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet. 1992;339:1523–6. Citado en PubMed; PMID: 1351198.

  5. Law M, Wald N. Why heart disease mortality is low in France: the time lag explanation. Br Med J. 1999;318:1471-6. Citado en PubMed; PMID: 10346778.

  6. Chawla R. Regular drinking might explain the French paradox. Br Med J. 2004;329:1308. Citado en PubMed; PMID: 15576734.

  7. Pal S, Ho N, Santos C, Dubois P, Mamo J, Croft K, et al. Red wine polyphenolics increase LDL receptor expression and activity and suppress the secretion of ApoB100 from human HepG2 cells. J Nutr. 2003;133(3):700-6. Citado en PubMed; PMID: 12612140.

  8. Stocker R, O'Halloran RA. Dealcoholized red wine decreases atherosclerosis in apolipoprotein E gene-deficient mice independently of inhibition of lipid peroxidation in the artery wall. Am J Clin Nutr. 2004;79:123-30. Citado en PubMed; PMID: 14684408.

  9. Vinson JA, Mandarano M, Hirst M, Trevithick JR, Bose P. Phenol antioxidant quantity and quality in foods: beers and the effect of two types of beer on an animal model of atherosclerosis. J Agric Food Chem. 2003;51:5528-33. Citado en PubMed; PMID: 12926909.

  10. Palmieri D, Pane B, Barisione C, Spinella G, Garibaldi S, Ghigliotti G. Resveratrol counteracts systemic and local inflammation involved in early abdominal aortic aneurysm development. J Surg Res. 2011;171(2):e237-46. Citado en PubMed; PMID: 21962734.

  11. Bhatt SR, Lokhandwala MF, Banday AA. Resveratrol prevents endothelial nitric oxide synthase uncoupling and attenuates development of hypertension in spontaneously hypertensive rats. Eur J Pharmacol. 2011;667(1-3):258-64. Citado en PubMed; PMID: 21640096.

  12. Crescente M, Jessen G, Momi S, Höltje HD, Gresele P, Cerletti C, et al. Interactions of gallic acid, resveratrol, quercetin and aspirin at the platelet cyclooxygenase-1 level. Functional and modelling studies. Thromb Haemost. 2009;102(2):336-46. Citado en PubMed; PMID: 19652885.

  13. Estruch R, Sacanella E, Mota F, Chiva-Blanch G, Antúnez E, Casals E, et al. Moderate consumption of red wine, but not gin, decreases erythrocyte superoxide dismutase activity: A randomised cross-over trial. Nutr Metab Cardiovasc Dis. 2011;21(1):46-53. Citado en PubMed; PMID: 19819677.

  14. Addolorato G, Leggio L, Ojetti V, Capristo E, Gasbarrini G, Gasbarrini A. Effects of short-term moderate alcohol administration on oxidative stress and nutritional status in healthy males. Appetite. 2008;50(1):50-6. Citado en PubMed; PMID: 17602789.

  15. Micallef M, Lexis L, Lewandowski P. Red wine consumption increases antioxidant status and decreases oxidative stress in the circulation of both young and old humans. Nutr J. 2007;6:27-35. Citado en PubMed; PMID: 17888186.

  16. Tsang C, Higgins S, Duthie GG, Duthie SJ, Howie M, Mullen W, et al. The influence of moderate red wine consumption on antioxidant status and indices of oxidative stress associated with CHD in healthy volunteers. Br J Nutr. 2005;93(2):233-40. Citado en PubMed; PMID: 15788107.

  17. Rajdl D, Racek J, Trefil L, Siala K. Effect of white wine consumption on oxidative stress markers and homocysteine levels. Physiol Res. 2007;56(2):203-12. Citado en PubMed; PMID: 16555941.

  18. Estruch R, Sacanella E, Badia E, Antúnez E, Nicolás JM, Fernández-Solá J, et al. Different effects of red wine and gin consumption on inflammatory biomarkers of atherosclerosis: a prospective randomized crossover trial. Effects of wine on inflammatory markers. Atherosclerosis. 2004;175(1):117-23. Citado en PubMed; PMID: 15186955.

  19. Djurovic S, Berge KE, Birkenes B, Braaten O, Retterstol L. The effect of red wine on plasma leptin levels and vasoactive factors from adipose tissue: a randomized crossover trial. Alcohol Alcohol. 2007;42(6):525-8. Citado en PubMed; PMID: 17670801.

  20. Chiva-Blanch G, Urpi-Sarda M, Llorach R, Rotches-Ribalta M, Guillén M, Casas R, et al. Differential effects of polyphenols and alcohol of red wine on the expression of adhesion molecules and inflammatory cytokines related to atherosclerosis: a randomized clinical trial. Am J Clin Nut. 2012;95(2):326-34. Citado en PubMed; PMID: 22205309.

  21. Kohsaka S, Jin Z, Rundek T, Homma S, Sacco RL, Di Tullio MR. Alcohol consumption and atherosclerotic burden in the proximal thoracic aorta. Atherosclerosis. 2011; 219(2):794-8. Citado en PubMed; PMID: 21885050.

  22. Park H, Kim K. Association of alcohol consumption with lipid profile in hypertensive men. Alcohol Alcohol. 2012;47(3):282-7. Citado en PubMed; PMID: 22371847.

  23. Magnus P, Bakke E, Hoff DA, Høiseth G, Graff-Iversen S, Knudsen GP, et al. Controlling for high-density lipoprotein cholesterol does not affect the magnitude of the relationship between alcohol and coronary heart disease. Circulation. 2011;124(21):2296-302. Citado en PubMed; PMID: 22042888.

  24. Avellone G, Di Garbo V, Campisi D, De Simone R, Raneli G, Scaglione R, et al. Effects of moderate Sicilian red wine consumption on inflammatory biomarkers of atherosclerosis. Eur J Clin Nutr. 2006; 60(1):41-7. Citado en PubMed; PMID: 16132058.

  25. Chiva-Blanch G, Urpi-Sarda M, Ros E, Valderas-Martinez P, Casas R, Arranz S, et al. Effects of red wine polyphenols and alcohol on glucose metabolism and the lipid profile: a randomized clinical trial. Clin Nutr. 2013;32(2). Citado en PubMed; PMID: 22999066.

  26. Koppes LL, Dekker JM, Hendriks HF, Bouter LM, Heine RJ. Moderate alcohol consumption lowers the risk of type 2 diabetes: a meta-analysis of prospective observational studies. Diabetes Care. 2005;28(3):719-25. Citado en PubMed; PMID: 15735217.

  27. Baliunas DO, Taylor BJ, Irving H, Roerecke M, Patra J, Mohapatra S, et al. Alcohol as a risk factor for type 2 diabetes: A systematic review and meta-analysis. Diabetes Care. 2009;32(11):2123-32. Citado en PubMed; PMID: 9875607.

  28. Mekary RA, Rimm EB, Giovannucci E, Stampfer MJ, Willett WC, Ludwig DS, et al. Joint association of glycemic load and alcohol intake with type 2 diabetes incidence in women. Am J Clin Nutr. 2011;94(6):1525-32. Citado en PubMed; PMID: 22049168.

  29. Sierksma A, Patel H, Ouchi N, Kihara S, Funahashi T, Heine RJ, et al. Effect of moderate alcohol consumption on adiponectin, tumor necrosis factoralpha, and insulin sensitivity. Diabetes Care. 2004;27(1):184-9. Citado en PubMed; PMID: 14693987.

  30. Beulens JW, Van Beers RM, Stolk RP, Schaafsma G, Hendriks HF. The effect of moderate alcohol consumption on fat distribution and adipocytokines. Obesity (Silver Spring). 2006;14(1):60-6. Citado en PubMed; PMID: 16493123.

  31. Naissides M, Mamo JCL, James AP, Pal S. The effect of chronic consumption of red wine on cardiovascular disease risk factors in postmenopausal women. Atherosclerosis. 2006;185(2):438-45. Citado en PubMed; PMID: 16095600.

  32. Kim SH, Abbasi F, Lamendola C, Reaven GM. Effect of moderate alcoholic beverage consumption on insulin sensitivity in insulinresistant, nondiabetic individuals. Metabolism. 2009;58(3):387-92. Citado en PubMed; PMID: 19217456.

  33. Napoli R, Cozzolino D, Guardasole V, Angelini V, Zarra E, Matarazzo M, et al. Red wine consumption improves insulin resistance but not endothelial function in type 2 diabetic patients. Metabolism. 2005;54(3):306-13. Citado en PubMed; PMID: 15736107.

  34. Bau PF, Bau CH, Rosito GA, Manfroi WC, Fuchs FD. Alcohol consumption, cardiovascular health, and endothelial function markers. Alcohol. 2007;41(7):479- 88. Citado en PubMed; PMID: 17980786.

  35. Toda N, Ayajiki K. Vascular actions of nitric oxide as affected by exposure to alcohol. Alcohol Alcohol. 2010;45(4):347-55. Citado en PubMed; PMID: 20522422.

  36. Tousoulis D, Ntarladimas I, Antoniades C, Vasiliadou C, Tentolouris C, Papageorgiou N, et al. Acute effects of different alcoholic beverages on vascular endothelium, inflammatory markers and thrombosis fibrinolysis system. Clin Nutr. 2008;27(4):594-600. Citado en PubMed; PMID: 18295937.

  37. Kiviniemi TO, Saraste A, Lehtimäki T, Toikka JO, Saraste M, Raitakari OT, et al. Decreased endothelin-1 levels after acute consumption of red wine and dealcoholized red wine. Atherosclerosis. 2010;211(1):283-6. Citado en PubMed; PMID: 20137789.

  38. Taylor B, Irving HM, Baliunas D, Roerecke M, Patra J, Mohapatra S, et al. Alcohol and hypertension: gender differences in dose-response relationships determined through systematic review and meta-analysis. Addiction. 2009;104(12):1981-90. Citado en PubMed; PMID: 19804464.

  39. Chiva-Blanch G, Urpi-Sarda M, Ros E, Arranz S, Valderas-Martínez P, Casas R et al. Dealcoholized red wine decreases systolic and diastolic blood pressure and increases plasma nitric oxide. Circ Res. 2012;111(8):1065-8. Citado en PubMed; PMID: 22955728.

  40. Chiva-Blanch G, Arranz S. Lamuela-Raventos, RM. Estruch, R. Effects of Wine, Alcohol and Polyphenols on Cardiovascular Disease Risk Factors. Alcohol Alcohol. 2013;48(3):270-7. Citado en PubMed; PMID: 23408240.

  41. Pomp ER, Rosendaal FR, Doggen CJ. Alcohol consumption is associated with a decreased risk of venous thrombosis. Thromb Haemost. 2008;99(1):59-63. Citado en PubMed; PMID: 18217135.

  42. Reynolds K, Lewis B, Nolen JD, Kinney GL, Sathya B, He J. Alcohol consumption and risk of stroke: a meta-analysis. Jama. 2003;289(21):579-88. Citado en PubMed; PMID: 12578491.

  43. Rifler JP, Lorcerie F, Durand P, Delmas D, Ragot K, Limagne E, et al. A moderate red wine intake improves blood lipid parameters and erythrocytes membrane fluidity in post myocardial infarct patients. Mol Nutr Food Res. 2012;56(2):345-51. Citado en PubMed; PMID: 22419533.

  44. Costanzo S, Di Castelnuovo A, Donati MB, Iacoviello L, De Gaetano G. Wine, beer or spirit drinking in relation to fatal and non-fatal cardiovascular events: a meta-analysis. Eur J Epidemiol. 2011;26(11):833-50. Citado en PubMed; PMID: 22076059.

  45. Whitfield JB, Heath AC, Madden PA, Pergadia ML, Montgomery GW, Martin NG. Metabolic and biochemical effects of low-to-moderate alcohol consumption. Alcohol Clin Exp Res. 2013;37(4). Citado en PubMed; PMID: 23134229.

  46. Di Minno MN, Franchini M, Russolillo A, Lupoli R, Iervolino S, Di Minno G. Alcohol dosing and the heart: updating clinical evidence. Semin ThrombHemost. 2011;37(8):875-84. Citado en PubMed; PMID: 22198852.

  47. Romelsjö A, Allebeck P, Andréasson S, Leifman A. Alcohol, mortality and cardiovascular events in a 35 year follow-up of a nationwide representative cohort of 50 000 Swedish conscripts up to age 55. Alcohol Alcohol. 2012;47(3):322-7. Citado en PubMed; PMID: 22387338.

  48. Guilford JM, Pezzuto JM. Wine and health: a review. Am J Enol Vitic 2011 ;62:471–86.

  49. Zhang H, Woodams EE, Hang YD. Factors affecting the methanol content and yield of plum brandy. J Food Sci. 2012;77(4):T79-82. Citado en PubMed; PMID: 22393882.




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