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2005, Número 4

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Cir Cir 2005; 73 (4)


Tratamiento multidisciplinario para cáncer del recto: ¿evolución o estatismo?

Luna-Pérez P

Idioma: Español
Referencias bibliográficas: 19
Paginas: 249-250
Archivo PDF: 74.79 Kb.


FRAGMENTO

Respecto al tratamiento clásico del paciente con cáncer de recto y factores de riesgo (ganglios linfáticos metastásicos), en estudios prospectivos y sorteados se ha demostrado que la administración posoperatoria de quimioterapia y radioterapia mejora el control local y la sobrevida al hacer la comparación con pacientes tratados con cirugía radical.


REFERENCIAS (EN ESTE ARTÍCULO)

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  3. 3. Krook JE, Moertel CG, Gunderson LL, et al. Effective surgical adjuvant therapy for high-risk rectal carcinoma. N Engl J Med 1991;324:709-715.

  4. 4. Luna-Perez P, Rodriguez-Ramirez S, Vega J, Sandoval E, Labastida S. Morbidity and mortality following abdominoperineal resection for low rectal adenocarcinoma. Rev Invest Clin 2001;53:388-95.

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  6. 6. Luna-Perez P, Castro J, Delgado S, Labastida S, Cruz y Celiz M, Herrera L. Local recurrence of rectal adenocarcinoma following preoperative radiation therapy and surgery. Arch Med Res 1992;23:183-188.

  7. 7. Bosset JF, Mantion G, Lorchel F, et al. Adjuvant and neoadjuvant radiation therapy for rectal cancer. Semin Oncol 2000;27:60-65.

  8. 8. Luna-Perez P, Barrientos H, Delgado S, Morales A. Usefulness of frozen section examination in resected mid-rectal cancer after preoperative radiation. Am J Surg 1990;156:582-584.

  9. 9. Luna-Perez P, Rodriguez D, Ortiz N, Labastida S, Delgado S, Herrera L. Sphincter-saving surgery with and without preoperative radiation therapy as treatment for adenocarcinoma of the mid-rectum. Surg Oncol (Oxford) 1995;4:223-229.

  10. Swedish Rectal Cancer Trial Group. Improved survival with preoperative radiotherapy in resectable rectal cancer. N Engl J Med 1997;336:980-987.

  11. Medical Research Council Rectal Cancer Working Party. Randomized trial of surgery alone versus radiotherapy followed by surgery for potentially operable advanced rectal cancer. Lancet 1996;348:1605-1610.

  12. Bosset JF, Pavy JJ, Hamers HP, et al. Determination of the optimal dose of 5-fluorouracil when combined with low dose D,L-leucovorin and irradiation in rectal cancer: results of three consecutive phase II studies—EORTC Radiotherapy Group. Eur J Cancer 1993;29A:1406-1410.

  13. Sanchez W, Luna-Perez P, Alvarado I, Labastida S, Herrera L. Modified clearing technique to identify lymph node metastases in post-irradiated surgical specimens from rectal adenocarcinoma. Arch Med Res 1996;27:31-36.

  14. Bosset JF, Calais G, Mineur L, et al. Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer: preliminary results—EORTC 22921. J Clin Oncol 2005;23:5620-5627.

  15. Sauer R, Becker H, Hohenberger W, et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 2004;351:1731-1739.

  16. Luna-Perez P, Trejo-Valdivia B, Labastida S, Garcia S, Rodriguez D, Delgado S. Prognostic factors of locally advanced rectal Adenocarcinoma treated with preoperative radiation therapy and radical surgery. World J Surg 1999;23:1069-1075.

  17. Luna-Perez P, Arriola E L, Cuadra Y, Alvarado I, Quintero A. p53 protein overexpression and response to induction chemo-radiation therapy in patients with locally advanced rectal adenocarcinoma. Ann Surg Oncol 1998;5:203-208.

  18. Luna-Perez P, Segura J, Alvarado I, Labastida S, Santiago-Payan H, Quintero A. Specific c-K-ras Gene mutations as a tumor-response marker in locally advanced rectal cancer treated with preoperative chemo-radiotherapy. Ann Surg Oncol 2000;7:727-731.

  19. Habr-Gama A, Perez Oliva R, Nadalin W. Long-term results of preoperative chemoradiation for distal rectal cancer correlation between final stage and survival. J Gastrointest Surg 2005;9:90-101.




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