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Academia Mexicana de Neurología, A.C.

2009, Número 4

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Rev Mex Neuroci 2009; 10 (4)


Restauración cerebral: Una función del sueño

Acosta-Peña E, García-García F

Idioma: Español
Referencias bibliográficas: 76
Paginas: 274-280
Archivo PDF: 244.00 Kb.


RESUMEN

En los humanos el sueño abarca casi una tercera parte de la vida. Aunque el número de horas de sueño varía de acuerdo con las exigencias del medio y del propio individuo, es un hecho inobjetable que tanto humanos como animales necesitan dormir para mantener la homeostasis del organismo. Evidencias experimentales señalan que la vigilia prolongada favorece el estrés oxidativo, disminuye la neurogénesis e induce apoptosis neuronal, entre otros eventos dañinos para el cerebro; de ahí que se sugiera que una de las funciones del sueño es favorecer la restauración o mantenimiento neuronal para compensar al cerebro del desgaste sufrido durante la vigilia. En la presente revisión se describen, en primer lugar, los aspectos generales de la biología del ciclo vigilia-sueño y posteriormente se dan a conocer las evidencias más importantes que apoyan la hipótesis restauradora del sueño. Aunque es poco el trabajo que se ha realizado sobre el tema, la información que existe es suficiente para darse cuenta de la importancia que el sueño tiene en el mantenimiento y la conservación de la integridad cerebral.


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