2001, Número 6
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Med Crit 2001; 15 (6)
Monitoreo de la presión tisular de oxígeno cerebral: una herramienta para prevenir y tratar la isquemia cerebral traumática
Carmona SJA, Van den Brink W, Van Santbrink H, Hogesteeger C, Steyerberg PE, Sosa EL, Mass A
Idioma: Español
Referencias bibliográficas: 189
Paginas: 185-202
Archivo PDF: 244.85 Kb.
RESUMEN
Objetivo: Presentar nuestra experiencia en el monitoreo de la oxigenación cerebral con el propósito de promover esta técnica en México para la atención del trauma severo.
Diseño: Estudio prospectivo entre 1992 y 1996.
Lugar: UCI de un hospital universitario de Rotterdam, Holanda.
Pacientes: Se incluyeron 101 pacientes (edad media 35 ± 17 años, rango 11-83 años).
Intervenciones: Con el propósito de prevenir, detectar y tratar la isquemia cerebral, se monitorizó la oxigenación cerebral mediante un catéter implantado en la materia blanca del encéfalo.
Mediciones y resultados principales: Se registró presión intracraneana (PIC), presión parcial de oxígeno tisular cerebral (PtO²c), presión arterial de CO² (PaCO²) la diferencia basal-final de ICP (DICP), ptO²c (DPtO²c) y PaCO² (DPaCO²), presión de perfusión cerebral, escala de coma de Glasgow y escala pronóstica de Glasgow (GOS). El pronóstico estuvo relacionado con la ICP y PtO²c/PaCO² e ICP y PtO²c/PaCO² (p 0.5).
Conclusión: Este procedimiento es una herramienta útil para el monitoreo del paciente crítico con trauma craneoencefálico severo.
REFERENCIAS (EN ESTE ARTÍCULO)
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Graham DI, Ford J, Adams JH, Doyle D, Teasdale GM, Lawrence AE, Mclelan DR. Ischemic brain damage is still common in fatal non-missile head injury. J Neurol Neurosurg Psychiatr, 1989;52:346-350.
Jones PA, Andrews PA, Midgley S et al. Measuring the burden of secondary in head injured patients during intensive care. J Neurosurg Anesthesiol 1994;6:4-14.
Miller JD, Becker DP. Secondary insults to the brain injured. JR Coll Sur Edinb 1982;27:292-298.
Chestnut RM, Marhsall LS, Klauber M. The role of secondary brain injury in determining outcome from severe head injury. J Trauma 1993;34:216.
Stochietti N, Furlan A, Volta L. Hypoxemia and arterial hypotension at the accident scene in head injury. J Trauma 1996;405:764-767.
Graham DI, Adams JH, Nicoll JAR, Maxwell WL, Gennarelli TA. The nature, distribution and causes of traumatic brain injury. Brain Pathology 1982;5:397-400.
Reilly PL, Adams JH et al. Patients with head injury who talk and die. Lancet 2:375-377.
Fernanside MR, Cook RJ, McDougall RJ. The westmead head injury project in severe head injury. A comparative analysis of prehospital, clinical and CT variables. Br J Neurossurg 1993;7:267-279.
Gentleman D, Jennett B. Audit of transfer of unconscious head injured patients to a neurosurgical unit. Lancet 1990;335:330-334.
Andrews PJD, Piper IR, Dearden NM, Miller JD. Secondary insults during intrahospital transport of head injured patients 1990;335:327-330.
Siegel JH, Gens DR, Mantov T, Geisler FH, Goordazi S, Mackenzi EL. Effect of associated injuries and blood volume replacement on death, rehabilitation needs, and disability in blunt traumatic brain injury. Crit Care Med 1991;19:1252-163.
Jenneti B. Minimising brain damage from head injury by appropriate early, management. In von Steinbuchel N, Von Cramon DY, Pople (eds). Neuropsychological rehabilitation, Springer, Berlin Heildeberg New York, 1992:139-145.
Becker DP, Miller JD, Ward JD et al. The outcome from severe head injury with early diagnosis and intensive management. J Neurosurg 1977;47:491-502.
Marmarou A, Andersen RL, Ward JD, Choi SC, Young HF, Eisenberg HM, Foulkes MA, Marshall LF, Jane JA. Impact of ICP instability and hypotension on outcome in patients with severe head trauma. J Neurosurg 1991;75:S59-S66.
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Valadka AB, Gopinath SP, Contant CF, Usura M, Robertson CS. Relationship of brain tissue PO2 to outcome after severe head injury. Critical Care Med 1998;26:1576-1581.
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Dings J, Meixensberg J, Roosen K. Brain tissue PO2-monitoring: catheterstability and complications. Neurological Res 1997:19:1-5.
Kiening KL, Untenberg AW, Bardt TF, Schenider GH, Lanksch WR. Monitoring of cerebral oxygenation in patients with severe head injuries: brain tissue PO2 versus jugular vein oxygen saturation. J Neurosurg 1996;85:751-757.
Dearden NM, Midgley S. Technical considerations in continuous jugular venous oxygen saturation in the management of severe head injury. Curr Opin Anaesth 1991;4:279-286.
Dearden NM. Jugular bulb venous oxygen saturation in the management of severe head injury. Acta Neurochir (Suppl) 1993;59:91-97.
Fortune JB, Feustel PI, Weigle CGM et al. Continuous measurement of jugular venous oxygen saturation in response to transient elevations of blood pressure in head-injured patients. J Neurosurg 1994;80:461-468.
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Lubbers DW, Baumgarrtl H, Zimelka W. Heterogeneity and stability of local PO2 distribution within the brain tissue. Adv Exp Med Biol 1994;345:567-574.
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Graham DI, Adams JH, Doyle D. Ischeamic brain damage in fatal non-missile head injuries. J Neurol Sci 1978;39: 213-234.
Graham DI, Ford J, Adams JH, Doyle D, Teasdale GM, Lawrence AE, Mclelan DR. Ischemic brain damage is still common in fatal non-missile head injury. J Neurol Neurosurg Psychiatr, 1989;52:346-350.
Jones PA, Andrews PA, Midgley S et al. Measuring the burden of secondary in head injured patients during intensive care. J Neurosurg Anesthesiol 1994;6:4-14.
Miller JD, Becker DP. Secondary insults to the brain injured. JR Coll Sur Edinb 1982;27:292-298.
Chestnut RM, Marhsall LS, Klauber M. The role of secondary brain injury in determining outcome from severe head injury. J Trauma 1993;34:216.
Stochietti N, Furlan A, Volta L. Hypoxemia and arterial hypotension at the accident scene in head injury. J Trauma 1996;405:764-767.
Graham DI, Adams JH, Nicoll JAR, Maxwell WL, Gennarelli TA. The nature, distribution and causes of traumatic brain injury. Brain Pathology 1982;5:397-400.
Reilly PL, Adams JH et al. Patients with head injury who talk and die. Lancet 2:375-377.
Fernanside MR, Cook RJ, McDougall RJ. The westmead head injury project in severe head injury. A comparative analysis of prehospital, clinical and CT variables. Br J Neurossurg 1993;7:267-279.
Gentleman D, Jennett B. Audit of transfer of unconscious head injured patients to a neurosurgical unit. Lancet 1990;335:330-334.
Andrews PJD, Piper IR, Dearden NM, Miller JD. Secondary insults during intrahospital transport of head injured patients 1990;335:327-330.
Siegel JH, Gens DR, Mantov T, Geisler FH, Goordazi S, Mackenzi EL. Effect of associated injuries and blood volume replacement on death, rehabilitation needs, and disability in blunt traumatic brain injury. Crit Care Med 1991;19:1252-163.
Jenneti B. Minimising brain damage from head injury by appropriate early, management. In von Steinbuchel N, Von Cramon DY, Pople (eds). Neuropsychological rehabilitation, Springer, Berlin Heildeberg New York, 1992:139-145.
Becker DP, Miller JD, Ward JD et al. The outcome from severe head injury with early diagnosis and intensive management. J Neurosurg 1977;47:491-502.
Marmarou A, Andersen RL, Ward JD, Choi SC, Young HF, Eisenberg HM, Foulkes MA, Marshall LF, Jane JA. Impact of ICP instability and hypotension on outcome in patients with severe head trauma. J Neurosurg 1991;75:S59-S66.
Miller JD, Becker D, Ward JD, Sullivan HG, Adams WE, Rosner MJ. Significance of intracranial hypertension in severe head injury. J Neurosurg 1977;47:503-516.
Langifttt TW, Gennarelli TA. Can the outcome from head injury be improved? J Neurosurg 1993;7:267-279.
Mock CN, Jurkovich GJ, nii-Amon-Kotei, Arreola-Risa C, Maier RV. Trauma mortality patterns in three nations at different economic levels: implications for global trauma system development. J Trauma 1998:44:804-812.
Archivo clínico del Hospital de Traumatología y Ortopedia “Victorio de la Fuente Narváez”. IMSS México, D.F. 1994.
Hernández M. Sistema de vigilancia epidemiológica de lesiones del área metropolitana del D.F. Dirección General de Epidemiología, Secretaría de Salud. S.A. 1998.
Rosner MJ, Rosner SD, Johnson AH. Cerebral perfusion pressure: management protocol and clinical results. J Neurosurg 1995;83:949-962.
Aaslid R, Marwalder TM, Normes H. Non-invasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries. J Neurosurg 1982;57:769-774.
Gopinath SP, Robertson CS, Contant CF et al. Jugular venous desaturation and outcome after head injury. J Neurol Neurosurg Psychiatr 1994;57:717-723.
Coplin WM, Okeefe GE, Grady MS, Grant GA, March KS, Win R, Lam AM. Accuracy of continuous jugular bulb saturation oximetry in the intensive care unit. Neurosurg 1998;423:533-539.
Bouma GJ, Muizellar JP, Choi SC et al. Ultra early evaluation of regional cerebral blood flow in severely head injured patients using xenon-enhanced computarized cerebral circulation and metabolism after severe head traumatic brain injury: the elusive role of ischemia. J Neurosurg 1991;75:88.
Obrist, Langfit TW, Jaggi JL. Cerebral blood flow an metabolism, in comatose patients with acute head injury: relationship to intracranial hypertension. J Neurosurg 1984;61: 241-253.
Lubbers DW. Oxygen electrodes and optodes and their application in vivo. Oxygen transport to tissue. ISSOT Edited by Ince et al. Plenum Press, New, York, 1996:13-14.
Van Santbrink H, Maas AIR, Avezaat CJJ. Continuous monitoring of partial pressure of brain tissue oxygen in patients with severe head injury. Neurosurg 1996;38:21-31.
Maas AIR, Fleckestein W, de Jong, Santbrink H. Tissue PO2. monitoring of cerebral oxygenation: experimental studies and preliminary clinical results of continuous monitoring of cerebrospinal fluid and brain tissue oxygen tension. Acta Neurochir (Suppl) 1993;59:50-57.
Doppenberg EMR, Zauner A, Bullock R et al. Determination of the ischemic threshold for the brain tissue oxygenation in the severely head injured patient. X intracranial pressure and neuromonitoring in brain injury, Williamsburg USA 1997;PO-2-056.
Dings J, Meixensberger J, Amschler J, Hamelbeck B et al. Brain tissue PO2 in relation to cerebral perfusion pressure, TCD findings and TCD reactivity after severe head injury. Acta Neurochir 1996;138:425-434.
Valadka AB, Gopinath SP, Contant CF, Usura M, Robertson CS. Relationship of brain tissue PO2 to outcome after severe head injury. Critical Care Med 1998;26:1576-1581.
Townsley M, Macmillan RK, Lee AK. Regulation of tissue oxygenation. Seminars in respiratory and critical care medicine 1995;5:361-372.
Schlichtig R, Tónnensen TI, Nemoto EM. Detecting disoxia in silent organs. Critical care state of art Edit Prough - Traystman by Society of Critical Care Medicine 1993;4:8,239-274,32.
Hagerdal MI, Harp L, Ni1sson, Siesjo BK. The effect of induced hypothermia upon oxygen consumption in the rat brain. J Neurochem 1975;24,311-316.
Van de Brink W, Van Santbrink H, Carmona SJA et al. Brain oxygenation tension in head injury. Neurosurg 2000;46(4):868-877.
Zauner A, Doppenberg E, Young HF et al. Brain oxygen monitoring predicts outcome after severe head injury. J Neurotrauma Abstract 1996;13:619.
Maas AIR, Dearden M, Teasdale GM, Braakman R, Cohadon F, Iannotti F, Karimi A, Lapierre F, Murray G, Ohman J. European Brain Injury Consortium (EBIC)- Guidelines for management of severe head injury in adults. Acta Neurochir (Wien) 1997;139:286-294.
Jennettt B, Bond M. Assessment of outcome after severe brain damage. A practical scale. The Lancet 1975:480-484.
Harrel FE. Desing: S-plus functions for biostatical/epidemiological modelling, testing, estimation, validations, graphics, prediction and type setting by storing enhanced model design atributes in the fit. Programs viable at Internet: http://lib.stat.cmu.edu. Accessed 1977.
Marshall LF, Marshall SB, Klauber MR et al. A new classification of head injury based on computarized tomography. J Neurosurg 1991;75:S14-S20.
Dings J, Meixensberg J, Roosen K. Brain tissue PO2-monitoring: catheterstability and complications. Neurological Res 1997:19:1-5.
Kiening KL, Untenberg AW, Bardt TF, Schenider GH, Lanksch WR. Monitoring of cerebral oxygenation in patients with severe head injuries: brain tissue PO2 versus jugular vein oxygen saturation. J Neurosurg 1996;85:751-757.
Dearden NM, Midgley S. Technical considerations in continuous jugular venous oxygen saturation in the management of severe head injury. Curr Opin Anaesth 1991;4:279-286.
Dearden NM. Jugular bulb venous oxygen saturation in the management of severe head injury. Acta Neurochir (Suppl) 1993;59:91-97.
Fortune JB, Feustel PI, Weigle CGM et al. Continuous measurement of jugular venous oxygen saturation in response to transient elevations of blood pressure in head-injured patients. J Neurosurg 1994;80:461-468.
Gopinath SP, Valadka AB, Uzura M, Robertson CS. Comparison of jugular venous oxygen saturation and brain tissue PO2 as monitor of cerebral ischemia after head injury. Crit Care Med 1999;27(11):2337-2345.
Latronico N, Beindorf AE, Rasuti FA, Febbrari P, Stefini. Limits of intermittent jugular bulb oxygen saturation monitoring in the management of severe head trauma patients. Neurosurg 2000:46(5):1131-38.
Stochetti N, Paparella A, Bridelli F et al. Cerebral venous oxygen saturation studied with bilateral samples in the internal jugular veins. Neurosurgery 1994;34:38-43.
Lubbers DW, Baumgarrtl H, Zimelka W. Heterogeneity and stability of local PO2 distribution within the brain tissue. Adv Exp Med Biol 1994;345:567-574.
van den Brink WA, Haitsma IK, Avezaat CJ. Houtsmuller AB, Kros JM, Maas AIR. The brain parenchyma/PO2-catheter interface: a histopathological study in the rat. J Neurotrauma 1998;15:813-8214.
Stoccheti N, Chieregato A, De Marci M, Croci M, Benti R, Grimoldi H. High cerebral perfusion pressure improves low values of local brain tissue O2 tension in focal lesions. Acta Neurochir Suppl (Wien) 1998;71:162-5.
Robertson C. Monitoring the dark side or the light side where to place the probe. Neurocritical care 2001, September 28-29 2001. Cleveland USA. The Clinical Clinic Foundation.
Anonymus. The use of hyperventilation in the acute management of severe head injury. Guidelines for the management of severe head injury. Joint Section on Neurotrauma and Critical Care. Brain. Trauma Foundation 1995:91-5.
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