2008, Número 5
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Rev Invest Clin 2008; 60 (5)
Biopsia de ganglio centinela después de la administración de quimioterapia neoadyuvante en pacientes con cáncer de mama: un estudio piloto prospectivo
Medina-Franco H, Salgado-Nesme N, Zerón-Medina-Cuairán J
Idioma: Ingles.
Referencias bibliográficas: 24
Paginas: 390-394
Archivo PDF: 49.93 Kb.
RESUMEN
Introducción. La viabilidad y la precisión de la biopsia del ganglio centinela en los pacientes que han recibido quimioterapia neoadyuvante para el tratamiento del cáncer de mama continúa siendo un tema controversial.
Material y métodos. Treinta y un pacientes con diagnóstico de carcinoma invasor de mama, en quienes se administró quimioterapia neoadyuvante, fueron sometidos a biopsia de ganglio centinela y disección axilar.
Resultados. El ganglio centinela fue identificado exitosamente en 26 (83.8%) pacientes. El ganglio fue positivo para malignidad en nueve (34.6%) pacientes. Dos de los pacientes con ganglio centinela negativo presentaron ganglios positivos en el espécimen histopatológico final de la disección axilar (porcentaje de falsos negativos: 18%).
Conclusiones. Los resultados obtenidos en nuestro estudio clínico prospectivo no apoyan el uso de la biopsia de ganglio centinela como un procedimiento preciso para predecir la positividad de los ganglios axilares.
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