2013, Número 1
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Rev Fac Med UNAM 2013; 56 (1)
Estatinas en adultos mayores, una población creciente
Soto HKA, Loza EO, García MN, Rodríguez GKG, Sánchez-Reyes L, Fanghänel SG
Idioma: Español
Referencias bibliográficas: 51
Paginas: 19-29
Archivo PDF: 219.68 Kb.
RESUMEN
El riesgo cardiovascular es responsable de un cuarto de las
muertes por enfermedad coronaria, y dentro de estos pacientes
el 75% son mayores de 65 años de edad, población
a la que nos enfocaremos en esta revisión. Por ello es de
suma importancia considerar tanto los beneficios clínicos
como económicos de una terapia preventiva en este grupo
poblacional. La prescripción en los ancianos se ha convertido
en la actualidad en una cuestión compleja que tiende a
incrementar el uso irracional de los fármacos, los errores de
medicación, los efectos adversos, así como la subutilización o
sobreutilización de los mismos. Las estatinas (inhibidores de
la HMG-CoA reductasa), son consideradas como el tratamiento
hipolipemiante de primera elección para la disminución
del riesgo cardiovascular y a pesar de no haber publicaciones
enfocadas en el uso exclusivo de estatinas en la población
de adultos mayores así como de múltiples controversias, se
pueden encontrar beneficios similares a los percibidos en
poblaciones más jóvenes, pero con un enfoque en prevención
primaria en la población de edad avanzada.
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