2004, Número 1
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Rev Mex Patol Clin Med Lab 2004; 51 (1)
Encefalitis por virus Nilo-Oeste: Epidemiología, ecología, diagnóstico y prevención
Carrada BT
Idioma: Español
Referencias bibliográficas: 51
Paginas: 6-15
Archivo PDF: 446.53 Kb.
RESUMEN
La encefalitis Nilo-Oeste es causada por el arbovirus del Nilo-Oeste,
que se ha venido propagando por Norteamérica. En el verano de 1999,
las muertes de los cuervos de Nueva York, las aves enfermas del
Zoológico del Bronx, y la presentación de un conglomerado inesperado
de casos de encefalitis, anunciaron la llegada del nuevo
Flavivirus
a los Estados Unidos. Aunque en 1999 sólo se registraron 62 casos y
siete defunciones, el virus se movió rápidamente a través del
continente, y en el 2002 hubo 4,156 casos y 284 defunciones. Hubo
otras epidemias recientes en Israel, Rumania, Rusia y en Canadá.
Los enfermos más viejos y aquellos usuarios de medicamentos
inmunosupresores, tuvieron mayor riesgo de neuroinfección,
caracterizada por daños a las meninges, el parénquima cerebral
o la médula espinal. En el 2002 se reconocieron pacientes con
parálisis flácida poliomielítica. Los intentos de aislar el virus
del suero o del líquido cefalorraquídeo no fueron exitosos, porque
las viremias fueron bajas y el virus había desaparecido cuando los
pacientes se presentaron. La titulación de la IgM en el suero y el
líquido cefalorraquídeo fue el método de diagnóstico más práctico
y eficiente. La prevención consiste en eliminar los criaderos de
mosquitos, uso racional de insecticidas, y evitar las picaduras
de los mosquitos, incluyendo el uso de repelentes. En este trabajo
se revisó la ecología-epidemiología y los cuadros clínicos producidos
por el virus Nilo-Oeste.
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