Palafox D, Llorente L

Idioma: Español
Referencias bibliográficas: 30
Paginas: 146-151
Archivo PDF: 93.72 Kb.

RESUMEN

La historia del estudio del mieloma múltiple se remonta a mediados del siglo XIX con la descripción de los primeros pacientes con la enfermedad. A partir de ese momento sobrevino una revolución en las áreas de la Medicina, Inmunología y Química que trajo consigo el descubrimiento de la estructura de las proteínas, novedosas técnicas de laboratorio y con ello, un hallazgo magistral por Henry Kunkel que cambió radicalmente la concepción que prevalecía sobre la fisiopatogenia del mieloma. El presente trabajo precisa los sucesos que llevaron a dilucidar la estructura química de las proteínas secretadas por células plasmáticas malignas.

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