2012, Número 02
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MediSan 2012; 16 (02)
El cáncer como respuesta adaptativa
Pérez CAE, Guerra CE, Rodríguez AOD
Idioma: Español
Referencias bibliográficas: 34
Paginas: 235-246
Archivo PDF: 322.37 Kb.
RESUMEN
Los adelantos en la biología celular y molecular han permitido una mejor comprensión
sobre el significado del cáncer. Muchos investigadores coinciden en cuanto a la
ocurrencia de la progresión tumoral de modo ordenado y secuencial en cada uno de los
tumores humanos más frecuentes, la presencia de “genes porteros y conserjes” que
regulan el sentido de dicha evolución, la naturaleza adaptativa de las mutaciones que
subyacen en la carcinogénesis, entre otras. Todo parece indicar que la variabilidad
genética inducida y el polimorfismo genético influyen determinantemente en la
susceptibilidad para el inicio de las neoplasias.
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