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2011, Número 4

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Cir Gen 2011; 33 (4)


Influencia de la inmunonutrición sobre el estado general, nutricional y estancia hospitalaria en pacientes postoperados de sepsis abdominal

González-Calatayud M, López-Romero S, Athié-Gutiérrez C, Valdovinos-González C, Urbina-León D

Idioma: Español
Referencias bibliográficas: 33
Paginas: 236-242
Archivo PDF: 88.03 Kb.


RESUMEN

Objetivo: Valorar el efecto del uso de glutamina con alimentación temprana, en pacientes con sepsis abdominal resuelta quirúrgicamente, sobre el estado general de salud (Apache II), el catabolismo proteico (nitrógeno ureico urinario), las complicaciones y la duración de la estancia hospitalaria.
Sede: Hospital General de México.
Diseño: Ensayo clínico controlado.
Analisis estadístico: Prueba t de Student.
Método: Se seleccionaron 24 pacientes con sepsis abdominal que requirieron resolución quirúrgica en la Unidad de Urgencias en el Hospital General de México. Luego de 24 a 72 h del evento quirúrgico, se inició la alimentación enteral en dos grupos: el primero con glutamina más alimentación estándar y el segundo con alimentación estándar. El día 1 y en el 3ro del postoperatorio se midieron niveles de laboratorio y nitrógeno ureico urinario, para determinar la clasificación Apache II, las complicaciones infecciosas y las no infecciosas, el balance nitrogenado y la duración de la estancia hospitalaria.
Resultados: No se encontró diferencia significativa en ninguno de los parámetros medidos entre el grupo de glutamina y el control; sin embargo, sí lo hubo en el valor de Apache II en el grupo de glutamina comparando intragrupo entre el primer día y el tercero (P ‹ 0.05).
Conclusiones: La alimentación enteral temprana suplementada con glutamina no presenta diferencia temprana en cuanto a la respuesta metabólica al trauma, estado nutricional ni utilización proteica.


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