Espinosa-de-los-Monteros A, Abarca L, Iglesias-Morales M

Idioma: Español
Referencias bibliográficas: 24
Paginas: 62-66
Archivo PDF: 246.77 Kb.

RESUMEN

Los pacientes con enfermedades autoinmunes del tejido conectivo tienen un mayor riesgo de desarrollar úlceras en los miembros inferiores. El propósito de este estudio fue evaluar la evolución de las úlceras de miembros inferiores en pacientes con enfermedades autoinmunes del tejido conectivo, particularmente después del empleo de autoinjertos cutáneos. Entre 2001 y 2009 se identificaron 15 úlceras de miembros inferiores en 8 pacientes con enfermedades autoinmunes del tejido conectivo, sin enfermedad vascular concomitante. En los casos en que no hubo control farmacológico de la enfermedad autoinmune, la aplicación de autoinjertos cutáneos culminó en falla terapéutica. En los casos en que hubo control farmacológico de la enfermedad autoinmune, tanto los autoinjertos cutáneos como los cuidados locales promovieron una cobertura cutánea estable. Las recaídas en la actividad de la enfermedad autoinmune provocaron recurrencia de la úlcera en el sitio cicatrizado en todos los casos. El desarrollo de cambios tisulares asociados a la enfermedad autoinmune se asocia con falla terapéutica.

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