Smit R, Lespi P, Gregorini D, Drut R

Idioma: Español
Referencias bibliográficas: 20
Paginas: 46-48
Archivo PDF: 136.83 Kb.

RESUMEN

El hallazgo de granulomas epitelioides ha sido ampliamente documentado en tumores sólidos y neoplasias hematológicas. Sin embargo, la existencia de granulomas con centro necrótico es una eventualidad infrecuente. Se comunica el caso de un varón de 27 años de edad, con adenomegalias cervicales, supraclaviculares y mediastinales. La histología de un ganglio supraclavicular reveló linfoma de Hodgkin variante celularidad mixta asociada con múltiples granulomas con necrosis que simula una linfadenitis tuberculosa o necrosante. La lesión era tan extensa que llevó a un diagnóstico inicial de linfadenitis granulomatosa. Consideramos que esta infrecuente asociación debe tenerse en cuenta, especialmente en pacientes jóvenes con sospecha de afectación ganglionar mediastinal en ausencia de tuberculosis sistémica.

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