Reyes SG, Mendizábal GR, Acosta GR, Ayala AA, Félix EI, Delgado HC, Monroy SA

Idioma: Español
Referencias bibliográficas: 31
Paginas: 138-142
Archivo PDF: 181.81 Kb.

RESUMEN

La enfermedad de Marchiafava-Bignami es caracterizada por desmielinización del cuerpo calloso. Las características clínicas son variadas, los síntomas más frecuentes inician como: demencia, alteración de la atención, dificultad para la marcha y síndrome de desconexión interhemisférica. Reporte de caso: caso clínico de paciente masculino de 69 años con antecedentes de alcoholismo, quien presentó alteración mental. La resonancia magnética reveló desmielinización del cuerpo calloso, sustancia blanca de hemisferio cerebral izquierdo y puente. La biopsia confirmó desmielinización sin evidencia de tumor. El diagnóstico de Marchiafava-Bignami fue confirmado. Conclusiones: este caso surge de preguntas acerca de algunas ideas previas sobre esta enfermedad, como pronóstico de sus formas agudas y el significado de lesiones extracallosas vistas mediante neuroimagen.

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