Ericka Montijo Barrios, Dante Bacarreza Nogales, Sergio Díaz Madero, Roberto Cervantes Bustamante, Norberto Mata Rivera, Flora Zárate Mondragón, Margarita García Campos, Lourdes López Portillo, Jaime Alfonso Ramírez Mayans

Idioma: Español
Referencias bibliográficas: 37
Paginas: 24-31
Archivo PDF: 157.33 Kb.

RESUMEN

Los probióticos son microorganismos vivos, no patógenos, resistentes a la digestión normal y que alcanzan el colon en forma viable, donde ejercen un efecto benéfico para el ser humano. Entre sus funciones destacan la protección de la mucosa, limitación de la traslocación bacteriana y la modulación del sistema inmunológico en el tracto gastrointestinal. Su utilidad clínica en pediatría se ha estudiado en enfermedades tanto digestivas como extraintestinales. En esta revisión se explora la utilidad de los probióticos en diversas patologías.

REFERENCIAS (EN ESTE ARTÍCULO)

1. Tannock GW. Molecular assessment of intestinal microflora. Am J Clin Nutr 2001;73:410S-4S.

2. O´Hara AM, Shanahan F. The gut flora as a forgotten organ. EMBO reports 2006;7:688-93.

3. Vandenplas Y, Ramírez-Mayans J, Castañeda-Guillot C. Consenso sobre el uso de probióticos en pediatría. Revista de Enfermedades Infecciosas en Pediatría 2002;15:144-51.

4. Fanaro S, Günther B, Garssen J, Knol J, Mosca F, Stahl B, Viggi V. Galacto oligosaccharides and long-chain fructo oligosaccharides as prebiotics in infant formulas: a review. Acta Paediatr 2005;94 (Suppl 449):22-6.

5. Buts JP. Mechanisms of action of biotherapeutic agents in vitro. In: Elmer GW, McFarland LV, Surawicz CM (Eds.). Biotherapeutic agents and infectious diseases. Humana Press. New Jersey, 1999. p. 27-46.

6. Sanders ME. Probiotics: definition, sources selection and uses. Clin Infect Dis 2008;46(Suppl 2):S58-61.

7. Lemberg DA, Ooi CY, Day AS. Probiotics in paediatric gastrointestinal diseases. J Paediatr Child Health 2007;43(5):331-6.

8. Salminen S, Bouley C, Boutron-Ruault MC, Cummings JH, Franck A, et al. Functional food science and gastrointestinal physiology and function. Br J Nutr 1998;80:S147-71.

9. Elmer G, McFarland LV. Biotherapeutic agents in the treatment of infectious diarrhoea. Gastroenterology Clinics 2001;30:100-14.

10. Buts J-P, Bernasconi P, Vaerman JP, et al. Stimulation of secretory IgA and secretory component of immunoglobulins in small intestine of rats treated with Saccharomyces boulardii. Dig Dis Sci 1990;35:251-6.

11. Buts JP, De Keyser N, De Raedemaeker L. Saccharomyces boulardii enhances rat intestinal enzyme expression by endoluminal release of polyamines. Pediatr Res 1994;36:522-7.

12. Jhonston BC, Supina AL, Ospina M, Vohra S. Probiotics for the prevention of pediatric antibiotic-associated diarrhoea. Cochrane Database of Systematic Reviews 2007, Issue 2. Art. No. CD004827.

13. McFarland LV. Meta-analysis of probiotics for the prevention of antibiotic associated diarrhoea and the treatment of Clostridium difficile disease. Am J Gastroenterol 2006;101:812-22.

14. Szajewska H, Ruszczynski M, Radzikowski A. Probiotics in the prevention of antibiotic-associated diarrhoea in children: a meta-analysis of randomized controlled trials. J Pediatr 2006;149:367-72.

15. Sazawal S, Hiremath G, Dhingra U, Malik P, Deb S, Black R. Efficacy of probiotics in the prevention of acute diarrhoea: a meta-analysis of masked, randomized, placebo-controlled trials. Lancet Infect Dis 2006;6:364-82.

16. Johnston BC, Supina AL, Vohra S. Probiotics for pediatric-associated diarrhoea: a meta-analysis of randomized placebo-controlled trials. CMAJ 2006;175(4):377-83.

17. Szajewska H, Mrujowicz J. Meta-analysis: non-pathogenic yeast Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea. Aliment Pharmacol Ther 2005;22:365-72.

18. D´Souza AL, Rajkumar C, Cooke J, Bulpitt CJ. Probiotics in prevention of antibiotic associated diarrhoea: meta-analysis. BMJ 2002;324:1361-66.

19. Cremonini F, Di Caro S, Nista EC, Bartolozzi F, Capelli G, et al. Meta-analysis: the effect of probiotic administration on antibiotic-associated diarrhoea. Aliment Pharmacol Ther 2002;16:1461-7.

20. McFarland LV. Meta-analysis of probiotics for the prevention of traveler’s diarrhoea. Travel Med Infect Dis 2007;5(2):97-105.

21. Szajewska H, Skórka A, Dylag M. Meta-analysis: Saccharomyces boulardii for treating acute diarrhoea in children. Aliment Pharmacol Ther 2007;25:257-64.

22. Allen SJ, Okoko B, Martinez E, Gregorio G, Dans LF. Probiotics for treating infectious diarrhoea. Cochrane Database of Systematic Reviews 2003, Issue 4. Art. No: CD003048.

23. Van Niel CW, Feudtner C, Garrison MM, Christakis DA. Lactobacillus therapy for acute infectious diarrhoea in children: a meta-analysis. Pediatrics 2002;109:678-84.

24. Huang JS, Bousvaros A, Lee JW, Diaz A, Davidson EJ. Efficacy of probiotic use in acute diarrhea in children: a meta-analysis. Dig Dis Sci 2002; 47(11):2625-34.

25. Huang JS, Bousvaros A, Lee JW, Diaz A, Davidson EJ. Efficacy of probiotic use in acute diarrhoea in children: a meta-analysis. Dig Dis Sci 2002;47(11):2625-34.

26. AlFaleh K, Bassler D. Probiotics for prevention of necrotizing enterocolitis in preterm infants. Cochrane Database of Systematic Reviews 2008, Issue 1. Art. No: CD005496.

27. Hoyos AB. Reduced incident of necrotizing enterocolitis associated with enteral administration of Lactobacillus acidophilus and Bifidobacterium infantis to neonates in an intensive care unit. Int J Infect Dis 1999;3(4):197-202.

28. Forero J, Vera LM. Efectividad de un uso de un probiótico multiespecie en la prevención de enterocolitis necrotizante en recién nacidos de pretérmino. MedUNAB 2005;8(1):5-10.

29. Bin-Nun A, Bromiker R, Wilschanski M, Kaplan M, Rudensky B, Caplan M, Hammerman C. Oral probiotics reduce the incidence and severity of necrotizing enterocolitis in very low birth weight infants. J Pediatrics 2005;147:192-6.

30. Dani C, Biadaioli R, Bertini G, et al. Probiotics feeding in prevention of urinary tract infection, bacterial sepsis and necrotizing enterocolitis in preterm infants. Biol Neonate 2002;82:103-8.

31. Lin HC, Su BH, Chen AC, et al. Oral probiotics reduce the incidence and severity of necrotizing enterocolitis in very low birth weight infants. Pediatrics 2005;115:1-4.

32. Mallon P, McKay D, Kirk S, Gardiner K. Probiotics for induction of remission in ulcerative colitis. Cochrane Database of Systematic Reviews 2007, Issue 4. Art. No: CD005573.

33. Rolfe VE, Fortun PJ, Hawkey CJ, Bath-Hextall F. Probiotics for maintenance of remission in Cohn’s disease. Cochrane Database of Systematic Reviews 2006, Issue 4. Art. No: CD004826.

34. Wilhelm SM, Brubaker CM, Varcak EA, Kale-Pradhan PB. Effectiveness of probiotics in the treatment of irritable bowel syndrome. Pharmacotherapy 2008;28(4):496-505.

35. Lee J, Seto D, Bielory L. Meta-analysis of clinical trials of probiotics for prevention and treatment of pediatric atopic dermatitis. J Allergy Clin Immunol 2008;121:116-21.

36. Osborn DA, Slinn JK. Probiotics in infants for prevention of allergic disease and food hypersensitivity. Cochrane Database of Systematic Reviews 2007, Issue 4. Art. No: CD006475.

37. De Moreno de le Blanc A, Matar C, Perdigón G. The application of probiotics in cancer. Br J Nutr 2007;98(Suppl 1):S105-10.