2003, Número 3
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Rev Inst Nal Enf Resp Mex 2003; 16 (3)
Pasado, presente y futuro de las técnicas diagnósticas de tuberculosis
Zenteno CR
Idioma: Español
Referencias bibliográficas: 42
Paginas: 181-186
Archivo PDF: 60.54 Kb.
RESUMEN
Con 10 millones de nuevos casos y 3 millones de muertes cada año, la tuberculosis se mantiene como una de las enfermedades infecto-contagiosas de mayor impacto en la salud pública del mundo y requiere, de acuerdo a las entidades responsables de salud, una atención inmediata. Hasta ahora, los programas nacionales y globales de lucha contra la tuberculosis se han centrado en dos grandes rubros: 1) la identificación de individuos baciloscopico-positivos y, 2) su incorporación a programas de administración estrictamente supervisada de fármacos.
Si bien tales estrategias han permitido controlar y disminuir el número de casos, no está claro el papel que los sistemas de diagnóstico tradicionales tendrán para identificar pacientes baciloscópico negativos, con tuberculosis extrapulmonar y con infección latente, por lo que es importante empezar a cuestionar el futuro papel de los sistemas tradicionales de diagnóstico dentro de las estrategias a mediano y largo plazo de control y eliminación de la tuberculosis.
El objetivo principal de esta revisión es describir y evaluar las técnicas convencionales, las nuevas propuestas para el diagnóstico de la tuberculosis, y su necesidad de incorporarse en los futuros programas de control y eliminación.
REFERENCIAS (EN ESTE ARTÍCULO)
Maher D, Floyd K, Raviglione M. A strategic framework to decrease the burden of 2002.TB/HIV.WHO/CDS/TB/2002.296.(http://www.who.int/gtb/publications/tb_hiv/2002-296_index.htm).
Lennette EH, Balows A, Hasuler WJ, Truant JP. Microbiología clínica. 3ra ed. México: Interamericana, 1983.
World Health Organization. The world Health report 2000. Health systems: Improving performance: Geneva, 2000.
WHO Report 2003. Global Tuberculosis Control Surveillance, Planning, Financing. WHO/CDS/TB/2003.316. (http://www.who.int/gtb/publications/globrep/index.html).
Colebunders R, Bastian I. A review of the diagnosis and treatment of smear-negative pulmonary tuberculosis. Int J Tuberc Lung Dis 2000:4:97-107.
Heifets LB, Good RB. Current laboratory methods for the diagnosis of tuberculosis. In: Bloom BR, editores. Tuberculosis pathogenesis, protection and control. Washington: American Society for Microbiology, 1994:85-110.
Benjamin WH, Waities KB, Beverly A, Gibbs L, Waller M, Nix S, et al. Comparison of the MB/BacT system with a revised antibiotic supplement kit to the BACTEC 460 system for detection of mycobactera in clinical specimens. J Clin Microbiol 1998;36:3234-3238.
Pfyffer GE, Cieslack C, Welscher HM, Kissling P, Rusch-Gerdes S. Rapid detection of mycobacteria in clinical specimens by using the automated BACTEC 9000 MB system and comparison with radiometric and solid culture systems. J Clin Microbiol 1997; 35:2229-2234.
Pfyffer GE, Welscher HM, Kissling P, Cieslak C, Casal MJ, Gutiérrez J, et al. Comparison of the Mycobacteria growth indicator tube (MGIT) with radiometric and solid culture for recovery of acid-fast bacilli. J Clin Microbiol 1997;35:364-368.
Massó F, Sandoval S, Rosas P, Páez A, Díaz de León L, Zenteno E, et al. Eficacia de un ELISA con extracto proteico completo y deslipilizado de M. tuberculosis cepa H37Rv como prueba serológica para descartar tuberculosis pulmonar. Rev Lat Amer Microbiol 1993;35:177-184.
Lewis WR, Meeker H, Shuller-Levis G. Mycobacterial carbohydrate antigens for serological testing of patients with leprosy. J Infect Dis 1987;156:763-770.
Doherty TM, Demissie A, Olobo J, Wolday D, Britton S, Eguale T, et al. Immune responses to the Mycobacterium tuberculosis specific antigen ESAT 6, signal sub clinical infection among contacts of tuberculosis patients. J Clin Microbiol 2002; 40:704-706.
Arend SM, Engelhard AC, Groot G, De Boer K, Andersen P, Ottenhoff TH, et al. Tuberculin skin testing compared with T-cell responses to Mycobacterium tuberculosis-specific and nonspecific antigens for detection of latent infection in persons with recent tuberculosis contact. Clin Diagn Lab Immunol 2001;8:1089-1096.
FDA. New device approval-QuantiFERONÒ® - TB-P010033. Nov. 81, 2001. (http://www.fda.gov/cdrh/mda/docs/p010033.html).
Mazurek G, Villarino ME. Guidelines for using the QuantiFERON-TB test for diagnosing latent Mycobacterium tuberculosis infection. Morbidity and Mortality Weekly Report, 2003; 52:17-24.
Lalvani A, Pathan AA, Durkan H. Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigen specific T-cells. Lancet 2001;357:2017-2021.
Nakamura RM, Einck L, Belmonte MA. Detection of active tuberculosis by an MBP64 transdermal patch: a field study. Scan J Infect Dis 2001;33:405-407.
Pfyffer GE. Nucleic acid amplification for mycobacterial diagnosis. J Infect 1999; 39:21-26.
Scarparo C, Piccoli P, Rigon A, Ruggiero G, Scagnelli M, Piersimoni C. Comparison of enhanced Mycobacterium tuberculosis amplified direct test with COBAS AMPLICOR Mycobacterium tuberculosis assay for direct detection of Mycobacterium tuberculosis complex in respiratory and extrapulmonar specimens. J Clin Microbiol 2000;38:1559-1562.
Gamboa F, Manterola JM, Lonca J, Matas L, Cardona PJ, Padilla E, et al. Comparative evaluation of two commercial assays for direct detection of Mycobacterium tuberculosis in respiratory specimens. Eur J Clin Microbiol Infect Dis 1998;17:151-157.
Barnes PF. Rapid diagnostic tests for tuberculosis, progress but no gold standard. Am J Respir Crit Care Med 1997;155:1497-1498.
MMWR Nucleic Acid amplification tests for tuberculosis. MMWR Morb Mortal Wkly Rep 1996;45:950-952.
American Thoracic Society Workshop. Rapid diagnostic test for tuberculosis: what is the appropriate use? Am J Respir Crit Care Med 1997;155:1804-1814.
Centers for Disease Control and Prevention Update. Nucleic acid amplification tests for tuberculosis. JAMA 2000;284:826.
Kwiatkowska S, Marczak J, Zieba M, Nowak D. Clinical utility of a commercial ligase chain reaction kit for the diagnosis of smear-negative pulmonary tuberculosis. Int J Tubercle Lung Dis 1999;3:421-425.
Fadda G, Arditio F, Sanuinetti M, Posteraro B, Ortona L, Chezzi C, et al. Evaluation of the Abbot LCx Mycobacterium tuberculosis assay in comparison with culture methods in selected Italian patients. New Microbiol 1998;21:97-103.
Watterson SA, Wilson SM, Yates MD, Drobniewski FA. Comparison of three molecular assays for rapid detection of rifampin resistance in Mycobacterium tuberculosis. J Clin Microbiol 1998;36:1969-1973.
Beige J, Lokies J, Schaberg T, Finckh U, Fischer M, Mauch H, et al. Clinical evaluation of a Mycobacterium tuberculosis PCR assay. J Clin Microbiol 1995;33:90-95.
Hellyer TJ, Desjardin LE, Hehman GL, Cave MD, Eisenach KD. Quantitative analysis of mRNA as a marker for viability of Mycobacterium tuberculosis. J Clin Microbiol 1999;37:290-295.
Khan EA, Starke JR. Diagnosis of tuberculosis in children: increased need for better methods. Emerg Infect Dis 1995;1:115-123.
Woods GL, Bergmann JS, Williams-Bouyer N. Clinical evaluation of the Gen-Probe amplified Mycobacterium tuberculosis Direct Test for rapid detection of Mycobacterium tuberculosis in select nonrespiratory specimens. J Clin Microbiol 2001;39:747-749.
32. Hesseling AC, Schaaf HS, Gie RP, Starke JR, Beyers N. A critical review of diagnosis approaches used in the diagnosis of childhood tuberculosis. Int J Tuberc Lung Dis 2002;6:1038-1045.
Donald PR. Children and tuberculosis out of control? Curr Opin Pulm Med 2002; 8:178-182.
Zhang Y, Yound D. Molecular genetics of drug resistance in Mycobacterium tuberculosis. J Antimicrob Chemother 1994;34:313-319.
35. Warnon S, Zammatteo N, Alexandre I, Hans C, Remacle J. Colorimetric detection of the tuberculosis complex using cycling probe technology and hybridization in microplates. Biotechniques 2000;28:1152-1160.
36. Zerbi P, Schonau A, Bonetto S, Gori A, Costanzi G, Duca P, et al. Amplified in situ hybridization with peptide nucleic acid probes for differentiation of Mycobacterium tuberculosis complex and nontuberculous Mycobacterium species on formalin-fixed, paraffin-embedded archival biopsy and autopsy samples. Am J Clin Pathol 2001;116:770-775.
Rossi MC, Gori A, Zehender G, Marchetti G, Ferrario G, De Maddalena C, et al. A PCR-colorimetric microwell plate hybridization assay for detection of Mycobacterium tuberculosis and M. avium from culture samples and Ziehl-Neelsen-positive smears. J Clin Microbiol 2000;38:1772-1776.
Garza E, Guerrero M, Tijerina R, Viader JM. Identification of mycobacteria by mycolic acid pattern. Arch Med Res 1998;129:303-306.
Alugupalli S, Olson B, Larsson L. Detection of 2-ecosanol by gas chromatography-mass spectrometry in sputa from patients with pulmonary mycobacterial infections. J Clin Microbiol 1993;31:1575-1578.
Muranishi H, Nakashima M, Isobe R, Ando T, Shigematsu N. Measurement of tuberculostearic acid in sputa, pleural effusions and bronchial washing. A clinical evaluation for diagnosis of pulmonary tuberculosis. Diagn Microbiol Infect Dis 1990; 13:235-240.
Pérez-Rodríguez E, Jiménez CD. The use of adenosine deaminase and adenosine deaminase isoenzymes in the diagnosis of tuberculous pleuritis. Curr Opin Pulm Med 2000;6:259-266.
Norma Oficial Mexicana NOM-006SSA2-1993, para la prevención y control de la tuberculosis en la atención primaria a la salud, modificaciones. Publicada en el Diario Oficial de la Federación el martes 31 de octubre de 2000.