2004, Número 2
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Rev Salud Publica Nutr 2004; 5 (2)
Trigliceridos de cadena media en el tratamiento de obesidad.
Aguilera BMA, Alejandre VME, Milian SF
Idioma: Español
Referencias bibliográficas: 76
Paginas:
Archivo PDF: 163.79 Kb.
RESUMEN
En un diseño aleatorio simple se propuso como objetivo: determinar el efecto de los triglicéridos de cadena media (TCM) sobre la pérdida ponderal, cambios antropométrcios y séricos en obesos. Se estudiaron 24 sujetos de ambos sexos con edades de 25 a 38 años durante 3 meses. Se formaron 2 grupos; el grupo control con 11 sujetos, con régimen hipocalórico, lípidos (25%) en forma de triglicéridos de cadena larga (TCL), fibra (25g/día) y ejercicio moderado. El grupo tratado con 13 sujetos, mismo régimen pero con TCM al 50% y TCL 50% del 25% total de lipidos. Se realizó evaluación nutricia y determinaciones de: colesterol total, HDL y LDL, triglicéridos, glucosa total, ácido úrico, triyodotironina, tirosina y tirotropina en suero. En orina se determinó cuerpos cetónicos y urea. El análisis antropométrico, en cuanto a la pérdida ponderal fué de 1.7 Kg mayor en el grupo tratado (3 kg vs 4.7 kg, grupo control y tratado respectivamente) pero sin diferencia significativa. La diferencia del área muscular de brazo aumentó en el grupo tratado (4.54 mm
2 ± 18 tratado vs - 0.88 mm
2 ± 21 control) aunque sin llegar a una diferencia estadística (P›0.05). El pliegue cutaneo tricipital presentó una disminución en el grupo tratado mayor que el control (-20.24 ± 19.6 vs -12.9 ± 24.7 respectivamente) sin diferencia estadística. En cuanto al perfil lipídico se observó una mayor disminución en el colesterol total, LDL y triglicéridos en el grupo tratado a diferencia del grupo control, aunque las diferencias no fueron estadísticamente significativas (P›0.05). La pérdida de peso, determinaciones bioquimicas y riesgo cardiovascular no presentaron diferencias significativas en ambos grupos por lo que los TCM no son mayormente eficientes que los TCL de buena calidad en una dieta hipocalórica.
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