2009, Número 3
Helmintos parásitos de importancia veterinaria: regulación de la respuesta inmunitaria del portador y su uso potencial para el tratamiento de enfermedades inflamatorias
Bautista GCR
Idioma: Español/Inglés
Referencias bibliográficas: 149
Paginas: 283-291
Archivo PDF: 265.50 Kb.
RESUMEN
En años recientes ha llamado la atención una nueva alternativa para el tratamiento de enfermedades inflamatorias de humanos, como la enfermedad de Crohn, por medio de la administración oral de huevos del nematodo parásito de cerdos
Trichuris suis, con base en la capacidad que tienen los helmintos de polarizar la respuesta de las células T cooperadoras (Th) a una de tipo Th2 que inhibe la inflamación. En la presente revisión se analizan los mecanismos que utilizan los helmintos parásitos para modificar la respuesta inmunitaria del portador y se discute su uso potencial para el tratamiento de una variedad de enfermedades inflamatorias.
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