2009, Número 4
<< Anterior Siguiente >>
Med Crit 2009; 23 (4)
Tromboembolia pulmonar masiva: Caso clínico, manejo y revisión de la literatura
Bourlon CRA, Bourlon RC, Martínez MJ, Pérez PI, Vera UR, Herrera AV
Idioma: Español
Referencias bibliográficas: 23
Paginas: 234-240
Archivo PDF: 304.53 Kb.
RESUMEN
La tromboembolia pulmonar masiva es un padecimiento usualmente fatal en donde el diagnóstico y tratamiento tempranos son esenciales para disminuir la mortalidad. El criterio usual para dar el diagnóstico es la presencia de hipotensión arterial o choque cardiogénico, aunque la presentación clínica suele ser variable e inespecífica. El manejo inicial de todo paciente en el que se tenga la sospecha, es el soporte hemodinámico y ventilatorio, así como la valoración del inicio de la anticoagulación. Posteriormente, las alternativas terapéuticas definitivas incluyen la trombólisis y la embolectomía, existen diferentes parámetros que sugieren qué terapia seguir, pero debe de individualizarse la decisión a cada caso en particular.
REFERENCIAS (EN ESTE ARTÍCULO)
Horlander KT, Mannino DM et al. Pulmonary embolism mortality in the United States 1979-1998: an analysis using multiple-cause mortality data. Arch Intern Med 2003;163:1711.
Carson JL, Kelley MA et al. The clinical course of pulmonary embolism. N Engl J Med 1992;326:1240.
Tapson VF. Acute pulmonary embolism. N Engl J Med 2008;358:1037.
Kucher N, Goldhaber SZ. Management of massive pulmonary embolism. Circulation 2005;112:e28.
Guidelines on diagnosis and management of acute pulmonary embolism. Task Force on Pulmonary Embolism, European Society of Cardiology. Eur Heart J 2000;21:1301.
Kucher N, Rossi E et al. Massive Pulmonary Embolism. Circulation 2006;113:577-582.
Goldhaber SZ. Pulmonary embolism. Lancet 2004;363: 1295-1305.
Kucher N, Walpoth N et al. QR in V1: an ECG sign associated with right ventricular strain and adverse clinical outcome in pulmonary embolism. Eur Heart J 2003;24:1113-1119.
Pruszczyk P, Torbicki A et al. Diagnostic value of transoesophageal echocardiography in suspected hemodynamically significant pulmonary embolism. Heart 2001;85:628-634.
Schoepf UJ, Kucher N et al. Right ventricular enlargement on chest computed tomography: a predictor of early death in acute pulmonary embolism. Circulation 2004;110:3276-3280.
Schulman S, Beyth RJ et al. Hemorrhagic complications of anticoagulant and thrombolytic treatment: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008;133 Suppl 6:257.
Mercat A, Diehl JL et al. Hemodynamic effects of fluid loading in acute massive pulmonary embolism. Crit Care Med 1999;27:540-544.
Wood KE. Major pulmonary embolism: review of a pathophysiologic approach to the golden hour of hemodynamically significant pulmonary embolism. Chest 2002;121:877-905.
Lambermont B et al. Levosimendan: Right for the right ventricle? Crit Care Med 2007;35(8):1995-6.
Parissis J, Bistola V et al. Effects of levosimendan on right ventricular function in patients with advanced heart failure. Am J Cardiol 2006;98:1489-1492).
Leather HA, Ver Eycken K et al. Effects of levosimendan on right ventricular function and ventriculovascular coupling in open chest pigs. Crit Care Med 2003;31:2339-2343.
Slawsky MT, Colucci WS et al. Acute hemodynamic and clinical effects of levosimendan in patients with severe heart failure. Circulation 2000;102:2222-2227.
Buller HR, Agnelli G et al. Antithrombotic therapy for venous thromboembolic disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 2004;126:401S-428S.
Wan S, Quinlan DJ et al. Thrombolysis compared with heparin for the initial treatment of pulmonary embolism: a meta-analysis of the randomized controlled trials. Circulation 2004;110:744-749.
Decousus H, Leizorovicz A et al. A clinical trial of vena caval filters in the prevention of pulmonary embolism in patients with proximal deep-vein thrombosis. N Engl J Med 1998;338:409.
Aklog L, Williams CS et al. Acute pulmonary embolectomy: a contemporary approach. Circulation 2002;105:1416-1419.
Uflacker R. Interventional therapy for pulmonary embolism. J Vasc Interv Radiol 2001;12:147-164.
Schmitz-Rode T, Janssens U et al. Massive pulmonary embolism: percutaneous emergency treatment by pigtail rotation catheter. J Am Coll Cardiol 2000;36:375-380.