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2008, Número 3

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Bioquimia 2008; 33 (3)


Avances en la interacción entre micoplasmas y espermatozoides de humano

López-Hurtado M, Guerra-Infante FM

Idioma: Español
Referencias bibliográficas: 51
Paginas: 115-121
Archivo PDF: 112.82 Kb.


RESUMEN

El propósito de esta revisión es explorar y analizar los recientes descubrimientos sobre la adherencia y penetración de algunas especies de Mycoplasmas y evidenciar el papel de estas bacterias en el desarrollo de la infertilidad masculina. Desde los años 70 algunas especies de Mycoplasmas se han considerado como patógenos de células espermáticas, sin embargo varios estudios in vivo no han logrado confirmar las alteraciones espermáticas que se han observado en estudios in vitro. Los estudios in vitro han demostrado que Mycoplasma hominis, Mycoplasma vaginalis y Ureaplasma urealyticum son capaces de adherirse e internalizarse a espermatozoides humanos, aparentemente sin afectar la viabilidad de los mismos. La interacción de estos microorganismos produce una baja proporción de alteraciones morfológicas en las colas y la región media de los espermatozoides infectados, así como una disminución en la movilidad y en la reacción acrosómica. Estos hallazgos sugieren que la adherencia y la internalización son eventos tempranos en el proceso infeccioso, pero que su relación con la falla reproductiva debe de ser estudiada a fondo.


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