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Organo Oficial de la Sociedad Mexicana de Urología

2024, Número 3

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Rev Mex Urol 2024; 84 (3)


Correlación de la severidad de los síntomas del tracto urinario inferior con la diabetes mellitus en población masculina

Hernández-Vera BB, Morales-Pineda GX, Calderón-Lucas JF, Gómez-Franco TL, García-Martínez AF

Idioma: Español
Referencias bibliográficas: 41
Paginas: 1-12
Archivo PDF: 396.19 Kb.


RESUMEN

Objetivo: Determinar la correlación de la severidad de los STUI con la diabetes mellitus en población masculina.
Material y métodos: Estudio transversal y analítico en una unidad de medicina familiar en la Ciudad de México durante el año 2022, en 275 sujetos; se evaluó la severidad de los STUI mediante la Escala Visual Análoga Gea®, la medición de la diabetes mellitus (DM) fue por su tiempo de evolución, además, se estudió el consumo de diuréticos, café, cerveza y tabaco. El análisis fue por estadística descriptiva e inferencial mediante el coeficiente de correlación de Spearman (Rho).
Resultados: Solo se encontró correlación significativa en nicturia con DM (Rho 0.202) y correlaciones medias con algunos de los STUI en edad, diuréticos y tabaquismo; el 78.9 % refirió una buena calidad de vida.
Limitaciones del estudio: Estudiar al fenómeno en un diseño transversal como en las investigaciones previas, y no en uno longitudinal.
Originalidad: medir la cantidad de exposición de DM y otras covariables, permitiendo realizar correlaciones con los grados de severidad de los STUI, favoreciendo el análisis de causalidad del gradiente dosis respuesta.
Conclusiones: Las correlaciones entre diabetes y síntomas del tracto urinario inferior fueron débiles y medias, en su mayoría no significativas, a pesar de que hay literatura mencionando esta asociación, no es suficiente para deducir que la diabetes corresponda a un factor determinante en la severidad de los STUI.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. Saigal Cs, Joyce G. Economic costs of benignprostatic hyperplasia in the private sector. TheJournal of Urology. 2005;173(4). https://doi.org/10.1097/01.ju.0000152318.79184.6f

  2. Abler LL, Vezina CM. Links between lowerurinary tract symptoms, intermittent hypoxiaand diabetes: Causes or cures? RespiratoryPhysiology & Neurobiology. 2018;256: 87–96.https://doi.org/10.1016/j.resp.2017.09.009

  3. Choi EPH, Wan EYF, Chin WY, Lam CLK.Lower urinary tract symptoms and healthrelatedquality of life in Hong Kong primarycare: a cross-sectional study. Quality of LifeResearch. 2020;29(5): 1311–1321. https://doi.org/10.1007/s11136-019-02402-7.

  4. Robertson C, Link CL, Onel E, Mazzetta C,Keech M, Hobbs R, et al. The impact of lowerurinary tract symptoms and comorbidities onquality of life: the BACH and UREPIK studies.BJU International. 2007;99(2): 347–354. https://doi.org/10.1111/j.1464-410X.2007.06609.x.

  5. Boyle P, Robertson C, Mazzetta C, Keech M,Hobbs R, Fourcade R, et al. The relationshipbetween lower urinary tract symptomsand health status: the UREPIK study. BJUInternational. 2003;92(6): 575–580. https://doi.org/10.1046/j.1464-410X.2003.04448.x.

  6. Przydacz M, Skalski M, Sobanski J, ChlostaM, Raczynski K, Klasa K, et al. Associationbetween Lower Urinary Tract Symptoms andSleep Quality of Patients with Depression.Medicina. 2021;57(4): 394. https://doi.org/10.3390/medicina57040394.

  7. Perchon LFG, Pintarelli VL, Bezerra E, ThielM, Dambros M. Quality of life in elderlymen with aging symptoms and lower urinarytract symptoms (LUTS). Neurourology andUrodynamics. 2011;30(4): 515–519. https://doi.org/10.1002/nau.21008.

  8. Zheng Y, Ley SH, Hu FB. Global aetiology andepidemiology of type 2 diabetes mellitus and itscomplications. Nature Reviews Endocrinology.2018;14(2): 88–98. https://doi.org/10.1038/nrendo.2017.151.

  9. Boon TA, van Venrooij GEPM, Eckhardt MD.Effect of diabetes mellitus on lower urinarytract symptoms and dysfunction in patientswith benign prostatic hyperplasia. CurrentUrology Reports. 2001;2(4): 297–301. https://doi.org/10.1007/s11934-001-0067-z.

  10. Madersbacher S, Sampson N, Culig Z.Pathophysiology of Benign ProstaticHyperplasia and Benign Prostatic Enlargement:A Mini-Review. Gerontology. 2019;65(5): 458–464. https://doi.org/10.1159/000496289.

  11. Sebastianelli A, Gacci M. Current Status ofthe Relationship Between Metabolic Syndromeand Lower Urinary Tract Symptoms. EuropeanUrology Focus. 2018;4(1): 25–27. https://doi.org/10.1016/j.euf.2018.03.007.

  12. Tam CA, Helfand BT, Erickson BA. TheRelationship Between Diabetes, DiabetesSeverity, Diabetes Biomarkers, and thePresence of Lower Urinary Tract Symptoms:Findings From the National Health andNutrition Examination Survey. Urology.2017;105: 141–148. https://doi.org/10.1016/j.urology.2017.03.040.

  13. Vinik AI, Maser RE, Mitchell BD, FreemanR. Diabetic Autonomic Neuropathy. DiabetesCare. 2003;26(5): 1553–1579. https://doi.org/10.2337/diacare.26.5.1553.

  14. Sarma AV, Sauver JLS, Hollingsworth JM,Jacobson DJ, McGree ME, Dunn RL, et al.Diabetes Treatment and Progression of BenignProstatic Hyperplasia in Community-dwellingBlack and White Men. Urology. 2012;79(1):102–108. https://doi.org/10.1016/j.urology.2011.08.065.

  15. Menendez V, Cofan F, Talbot-Wright R, RicartMJ, Gutierrez R, Carretero P. UrodynamicEvaluation in Simultaneous Insulin-DependentDiabetes Mellitus and End Stage Renal Disease.The Journal of Urology. 1996;155(6). https://doi.org/10.1016/S0022-5347(01)66074-9.

  16. Johnson TV, Abbasi A, Ehrlich SS, Kleris RS,Schoenberg ED, Owen-Smith A, et al. PatientMisunderstanding of the Individual Questions ofthe American Urological Association SymptomScore. The Journal of Urology. 2008;179(6).https://doi.org/10.1016/j.juro.2008.01.140.

  17. Barry MJ, Fowler FJ, O’Leary MP, BruskewitzRC, Holtgrewe HL, Mebust WK, et al. TheAmerican Urological Association SymptomIndex for Benign Prostatic Hyperplasia. TheJournal of Urology. 1992;148(1). https://doi.org/10.1016/s0022-5347(17)36966-5.

  18. Johnson TV, Schoenberg ED, Abbasi A, EhrlichSS, Kleris R, Owen-Smith A, et al. Assessmentof the Performance of the American UrologicalAssociation Symptom Score in 2 Distinct PatientPopulations. The Journal of Urology. 2009;181(1).https://doi.org/10.1016/j.juro.2008.09.010.

  19. Preciado-Estrella DA, Kaplan SA, Iturriaga-Goyón E, Ramón-Trejo E, Mayorga-Gómez E,Auza-Benavides A, et al. Comparación del ÍndiceInternacional de Síntomas Prostáticos versusEscala Visual Análoga Gea® para la evaluaciónde los síntomas de la vía urinaria inferior.Revista mexicana de urología. 2017;77(5): 372–382. https://doi.org/10.24245/revmexurol.v77i5.1125.

  20. Daneshgari F, Liu G, Hanna-Mitchell AT.Path of translational discovery of urologicalcomplications of obesity and diabetes.American Journal of Physiology-Renal Physiology.2017;312(5): F887–F896. https://doi.org/10.1152/ajprenal.00489.2016.

  21. Costa HMLM, Popovicz D, Paes RG, AssisGM, Esmanhotto TC, Erzinger AR. Associaçãoentre neuropatia diabética e sintomas de tratourinário inferior nas pessoas com diabetesmellitus: revisão integrativa. Revista EletrônicaAcervo Saúde. 2020;12(12): e5574. https://doi.org/10.25248/reas.e5574.2020.

  22. Qasrawi H, Tabouni M, Almansour SW,Ghannam M, Abdalhaq A, Abushamma F, et al.An evaluation of lower urinary tract symptomsin diabetic patients: a cross-sectional study.BMC Urology. 2022;22(1): 178. https://doi.org/10.1186/s12894-022-01133-1.

  23. Erdogan BR, Liu G, Arioglu-Inan E, MichelMC. Established and emerging treatmentsfor diabetes-associated lower urinary tractdysfunction. Naunyn-Schmiedeberg’s Archives ofPharmacology. 2022;395(8): 887–906. https://doi.org/10.1007/s00210-022-02249-9.

  24. Tai HC, Tai TY, Yang WS, Wang SW, Yu HJ.Associations between lower urinary tractdysfunction and glycemic control in women withtype 2 diabetes: A cross-sectional study. Journalof Diabetes and its Complications. 2016;30(3):415–419. https://doi.org/10.1016/j.jdiacomp.2016.01.002.

  25. Lombardo R, Tubaro A, Burkhard F. Nocturia:The Complex Role of the Heart, Kidneys, andBladder. European Urology Focus. 2020;6(3):534–536. https://doi.org/10.1016/j.euf.2019.07.007.

  26. Ohishi M, Kubozono T, Higuchi K, AkasakiY. Hypertension, cardiovascular disease,and nocturia: a systematic review of thepathophysiological mechanisms. HypertensionResearch. 2021;44(7): 733–739. https://doi.org/10.1038/s41440-021-00634-0.

  27. Feldstein CA. Nocturia in arterial hypertension:a prevalent, underreported, and sometimesunderestimated association. Journal of theAmerican Society of Hypertension. 2013;7(1): 75–84. https://doi.org/10.1016/j.jash.2012.12.004.

  28. Johnson II TM, Sattin RW, Parmelee P, FultzNH, Ouslander JG. Evaluating PotentiallyModifiable Risk Factors for Prevalent andIncident Nocturia in Older Adults. Journal ofthe American Geriatrics Society. 2005;53(6):1011–1016. https://doi.org/10.1111/j.1532-5415.2005.53321.x.

  29. Chen FY, Dai YT, Liu CK, Yu HJ, Liu CY,Chen THH. Perception of nocturia and medicalconsulting behavior among communitydwellingwomen. International UrogynecologyJournal. 2007;18(4): 431–436. https://doi.org/10.1007/s00192-006-0167-x.

  30. Yoshimura K. Correlates for nocturia: A reviewof epidemiological studies. International Journalof Urology. 2012;19(4): 317–329. https://doi.org/10.1111/j.1442-2042.2011.02956.x.

  31. Welliver C, Sulaver R, Whittington A, HelfandBT, Çakır ÖO, Griffith JW, et al. AnalyzingWhy Men Seek Treatment for Lower UrinaryTract Symptoms and Factors AssociatedWith Nonimprovement. Urology. 2015;86(5):862–867. https://doi.org/10.1016/j.urology.2015.08.006.

  32. Conchado J, Álvarez R, Serrano C. Benignprostatic hyperplasia and lower tract urinarytract symptoms. Revi Cubana Med Gen Itegr2021; 37(1): 1-14.

  33. Maserejian NN, Chen S, Chiu GR, Araujo AB,Kupelian V, Hall SA, et al. Treatment Statusand Progression or Regression of Lower UrinaryTract Symptoms in a General Adult PopulationSample. The Journal of Urology. 2014;191.https://doi.org/10.1016/j.juro.2013.07.005.

  34. Alcántara Montero A, Brenes Bermúdez FJ,Pérez Feito D. Relationship between lowerurinary tract symptoms in men and erectiledysfunction. Semergen. 2016;42(3): 164–171.https://doi.org/10.1016/j.semerg.2015.07.005.

  35. Jura YH, Townsend MK, Curhan GC, ResnickNM, Grodstein F. Caffeine Intake, and theRisk of Stress, Urgency and Mixed UrinaryIncontinence. The Journal of Urology. 2011;185.https://doi.org/10.1016/j.juro.2011.01.003

  36. Bird ET, Parker BD, Kim HS, Coffield KS.Caffeine ingestion and lower urinary tractsymptoms in healthy volunteers. Neurourologyand Urodynamics. 2005;24(7): 611–615. https://doi.org/10.1002/nau.20179.

  37. Staack A, Distelberg B, Schlaifer A, Sabaté J.Prospective study on the effects of regular anddecaffeinated coffee on urinary symptoms inyoung and healthy volunteers. Neurourology andUrodynamics. 2017;36(2): 432–437. https://doi.org/10.1002/nau.22949.

  38. Kennedy OJ, Pirastu N, Poole R, FallowfieldJA, Hayes PC, Grzeszkowiak EJ, et al.Coffee Consumption and Kidney Function: AMendelian Randomization Study. AmericanJournal of Kidney Diseases. 2020;75(5): 753–761.https://doi.org/10.1053/j.ajkd.2019.08.025.

  39. Kovalev AV, Nikitin AM, Romanenko GH,Zavalishina LE. Pathomorphological alterationsin the kidneys in acute and chronic alcoholintoxication. Sudebno-Meditsinskaia Ekspertiza.2022;65(1): 52–56. https://doi.org/10.17116/sudmed20226501152.

  40. Jain G, Jaimes EA. Nicotine signaling andprogression of chronic kidney disease insmokers. Biochemical Pharmacology. 2013;86(8):1215–1223. https://doi.org/10.1016/j.bcp.2013.07.014.

  41. Ates M, Hosgorler F, Yuksel O, Unsal SK,Guvendi G, Karakilic A, et al. Nicotineincreased VEGF and MMP2 levels in the rat eyeand kidney. Environmental Science and PollutionResearch. 2019;26(32): 33517–33523. https://doi.org/10.1007/s11356-019-06460-9.




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