2024, Número 3
<< Anterior Siguiente >>
salud publica mex 2024; 66 (3)
Prediabetes, DT2 no diagnosticada, resistencia a la insulina y síndrome metabólico en Guanajuato, México
Guardado-Mendoza R, Vargas-Ortiz K, Reyes-Escodigo ML, Rodríguez-Cortés R, Evia-Viscarra L
Idioma: Ingles.
Referencias bibliográficas: 46
Paginas: 288-295
Archivo PDF: 267.94 Kb.
RESUMEN
Objetivo. Evaluar la prevalencia de prediabetes (PD), diabetes
tipo 2 no diagnosticada (DT2), síndrome metabólico, y
resistencia a la insulina, así como los factores de riesgo asociados
en población mexicana de Guanajuato, México.
Material
y métodos. Estudio transversal en población mexicana de
León, Guanajuato, México. Se realizó una evaluación clínica y
metabólica mediante curva de tolerancia oral a la glucosa; la
definición de PD, DT2, síndrome metabólico y resistencia a
la insulina se hizo de acuerdo a lineamientos internacionales.
Resultados. De los 1 470 participantes incluidos, 32.9%
tuvieron PD, 8.4% DT2, 48.1% síndrome metabólico, y 55.7%
resistencia a la insulina. Los principales factores de riesgo
asociados con DT2 y PD fueron obesidad central, sobrepeso,
acantosis nigricans, historia familiar de DT2, y edad.
Conclusiones.
La prevalencia de anormalidades en la glucosa,
síndrome metabólico y RI son altas en población mexicana,
y esto está relacionado con la alta prevalencia de múltiples
factores de riesgo en nuestra población.
REFERENCIAS (EN ESTE ARTÍCULO)
Basto-Abreu AC, López-Olmedo N, Rojas-Martínez R, Aguilar-SalinasCA, De la Cruz-Góngora V, Rivera-Dommarco J, et al. Prevalence of diabetesand glycemic control in Mexico: national results from 2018 and 2020.Salud Publica Mex. 2021;63(6):725-33. https://doi.org/10.21149/12842
Rull JA, Aguilar-Salinas CA, Rojas R, Rios-Torres JM, Gómez-PérezFJ, Olaiz G. Epidemiology of type 2 diabetes in Mexico. Arch Med Res.2005;36(3):188-96. https://doi.org/10.1016/j.arcmed.2005.01.006
Sun H, Saeedi P, Karuranga S, Pinkepank M, Ogurstova K, Duncan BB, etal. IDF Diabetes Atlas: Global, regional and country-level diabetes prevalenceestimates for 2021 and projections for 2045. Diabetes Res ClinPract. 2022;183:109119. https://doi.org/10.1016/j.diabres.2021.109119
Ferrannini E, Gastaldelli A, Iozzo P. Pathophysiology of prediabetes.Med Clin North Am. 2011;95(2):327-39. https://doi.org/10.1016/j.mcna.2010.11.005
Ogurtsova K, Guariguata L, Barengo NC, Lopez-Doriga-Ruiz P, SacreW, Karuranga S, et al. IDF diabetes Atlas: Global estimates of undiagnoseddiabetes in adults for 2021. Diabetes Res Clin Pract. 2022;183:109118.https://doi.org/10.1016/j.diabres.2021.109118
Urena-Bogarin EL, Martínez-Ramírez HR, Torres-Sánchez JR, Hernández-Herrera A, Cortés-Sanabrina L, Cueto-Mnazano A. Prevalence ofpre-diabetes in young Mexican adults in primary health care. Fam Pract.2015;32(2):159-64. https://doi.org/10.1093/fampra/cmu047
American Diabetes Association Professsional Practice Committee.Classification and Diagnosis of Diabetes: Standards of Medical Carein Diabetes-2022. Diabetes Care. 2022;45(suppl 1):S17-38. https://doi.org/10.2337/dc22-S002
Alberti KG, Eckel RH, Groundy SM, Zimmet PZ, Cleeman JI, Donato KA,et al. Harmonizing the metabolic syndrome: a joint interim statement of theInternational Diabetes Federation Task Force on Epidemiology and Prevention;National Heart, Lung, and Blood Institute; American Heart Association;World Heart Federation; International Atherosclerosis Society; and InternationalAssociation for the Study of Obesity. Circulation. 2009;120(16):1640-5. https://doi.org/10.1161/CIRCULATIONAHA.109.192644
Rojas-Martinez R, Aguilar-Salinas CA, Romero-Martínez M, Castro-PorrasL, Gómez-Velasco D, Mehta R. Trends in the prevalence of metabolicsyndrome and its components in Mexican adults, 2006-2018. Salud PublicaMex. 2021;63(6):713-24. https://doi.org/10.21149/12835
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, TurnerRC. Homeostasis model assessment: insulin resistance and beta-cellfunction from fasting plasma glucose and insulin concentrations in man.Diabetologia. 1985;28:412-9. https://doi.org/10.1007/BF00280883
Gayoso-Diz P, Otero-González A, Rodriguez-Alvarez MX, Gude F,García F, De Francisco A, et al. Insulin resistance (HOMA-IR) cut-off valuesand the metabolic syndrome in a general adult population: effect of genderand age: EPIRCE cross-sectional study. BMC Endocr Disord. 2013;13.https://doi.org/10.1186/1472-6823-13-47
Basto-Abreu A, López-Olmedo N, Rojas-Martínez R, Aguilar-SalinasCA, Moreno-Banda GL, Carnalla M, et al. Prevalencia de prediabetes ydiabetes en México: Ensanut 2022. Salud Publica Mex. 2023;65(suppl1):s163-8. https://doi.org/10.21149/14832
Hauguel-Moreau M, Hergault H, Cazabat L, Pépin M, Beauchet A, AidanV, et al. Prevalence of prediabetes and undiagnosed diabetes in a large urbanmiddle-aged population: the CARVAR 92 cohort. Cardiovasc Diabetol2023;22(31). https://doi.org/10.1186/s12933-023-01761-3
Lailler G, Piffaretti C, Fuentes S, Nabe HD, Oleko A, Cosson E, et al.Prevalence of prediabetes and undiagnosed type 2 diabetes in France:Results from the national survey ESTEBAN, 2014-2016. Diabetes Res ClinPract. 2020;165:108252. https://doi.org/10.1016/j.diabres.2020.108252
Rosella LC, Lebenbaum M, Fitzpatrick T, Zuk A, Booth GL. Prevalenceof prediabetes and undiagnosed diabetes in Canada (2007-2011) accordingto fasting plasma glucose and HbA1c screening criteria. Diabetes Care.2015;38(7):1299-305 https://doi.org/10.2337/dc14-2474
Mohammad A, Ziyab AH, Mohammad T. Prevalence of prediabetesand undiagnosed diabetes among Kuwaiti adults: a cross-sectional study.Diabetes Metab Syndr Obes. 2021;14:2167-76. https://doi.org/10.2147/DMSO.S296848
Makrilakis K, Kalpourtzi N, Ioannidis I, Iraklianou S, Raptis A, SotiropoulosA, et al. Prevalence of diabetes and pre-diabetes in Greece. Results of the First National Survey of Morbidity and Risk Factors (EMENO)study. Diabetes Res Clin Pract. 2021;172:108646. https://doi.org/10.1016/j.diabres.2020.108646
Mirahmadizadeh A, Fathalipour M, Mokhtari AM, Zeighami S, HassanipourS, Heiran A. The prevalence of undiagnosed type 2 diabetes andprediabetes in Eastern Mediterranean region (EMRO): A systematic reviewand meta-analysis. Diabetes Res Clin Pract. 2020;160:107931. https://doi.org/10.1016/j.diabres.2019.107931
Islam FM, Chakrabarti R, Islam MT, Wahab M, Lamoureux E, FingerRP, et al. Prediabetes, diagnosed and undiagnosed diabetes, their riskfactors and association with knowledge of diabetes in rural Bangladesh:The Bangladesh Population-based Diabetes and Eye Study. J Diabetes.
2016;8(2):260-8. https://doi.org/10.1111/1753-0407.1229420. Rannan-Eliya RP, Wijemunige N, Perera P, Kapuge Y, Gunawardana N,Sigera C, et al. Prevalence of diabetes and pre-diabetes in Sri Lanka: a newglobal hotspot-estimates from the Sri Lanka Health and Ageing Survey2018/2019. BMJ Open Diabetes Res Care. 2023;11(1):e003160. https://doi.org/10.1136/bmjdrc-2022-003160
Aguayo A, Urrutia I, González-Frutos T, Martínez R, Martínez-IndartL, Castaño L, et al. Prevalence of diabetes mellitus and impaired glucosemetabolism in the adult population of the Basque Country, Spain. DiabetMed. 2017;34(5):662-6. https://doi.org/10.1111/dme.13181
Basto-Abreu A, Barrientos-Gutiérrez T, Rojas-Martínez R, Aguilar-Salinas CA, López-Olmedo N, De la Cruz-Góngora V, et al. Prevalence ofdiabetes and poor glycemic control in Mexico: results from Ensanut 2016.Salud Publica Mex. 2020;62(1):50-9. https://doi.org/10.21149/10752
Fisher-Hoch SP, Vatcheva KP, Rahbar MH, McCormick JB. Undiagnoseddiabetes and pre-diabetes in health disparities. PLoS One.2015;10(7):e01331. https://doi.org/10.1371/journal.pone.0133135
Hellgren M, Hjorleifsdottir-Steiner K, Bennet L. Haemoglobin A1c asa screening tool for type 2 diabetes and prediabetes in populations ofSwedish and Middle-East ancestry. Prim Care Diabetes. 2017;11(4):337-43.https://doi.org/10.1016/j.pcd.2017.04.008
Thewjitcharoen Y, Elizabeth AJ, Butadej S, Nakasatien S, ChotwanviratP, Wanothayaroj E, et al. Performance of HbA1c versus oral glucosetolerance test (OGTT) as a screening tool to diagnose dysglycemic statusin high-risk Thai patients. BMC Endocr Disord. 2019;19(23). https://doi.org/10.1186/s12902-019-0339-6
Sardu C, D’Onofrio N, Balestrieri ML, Barbieri M, Rizzo MR, MessinaV, et al. Outcomes in patients with hyperglycemia affected by COVID-19:can we do more on glycemic control? Diabetes Care. 2020;43(7):1408-15.https://doi.org/10.2337/dc20-0723
Bello-Chavolla OY, Bahena-López JP, Antonio-Villa NE, Vargas-VázquezA, González-Díaz A, Márquez-Salinas A, et al. Predicting mortality due toSARS-CoV-2: a mechanistic score relating obesity and diabetes to COVID-19 outcomes in Mexico. J Clin Endocrinol Metab. 2020;105(8):2752-61. https://doi.org/10.1210/clinem/dgaa346
Alegre-Diaz J, Herrington W, López-Cervantes M, Gnatiuc L, Ramirez R,Hill M, et al. Diabetes and cause-specific mortality in Mexico City. N Engl JMed. 2016;375:1961-71. https://doi.org/10.1056/NEJMoa1605368
Aroda VR, Knowler WC, Crandall JP, Perreault L, Edelstein SL, JeffriesSL, et al. Metformin for diabetes prevention: insights gained from the DiabetesPrevention Program/Diabetes Prevention Program Outcomes Study.Diabetologia. 2017;60:1601-11. https://doi.org/10.1007/s00125-017-4361-9
Bello-Chavolla OY, Antonio-Villa NE, Fermín-Martínez CA, Fernández-Chirino L, Vargas-Vázquez A, Ramírez-García D, et al. Diabetes-relatedexcess mortality in Mexico: a comparative analysis of national death registriesbetween 2017-2019 and 2020. Diabetes Care. 2022;45(12):2957-66.https://doi.org/10.2337/dc22-0616
Gong Q, Zhang P, Wang J, Ma J, An Y, Chen Y, et al. Morbidity and mortalityafter lifestyle intervention for people with impaired glucose tolerance:30-year results of the Da Qing Diabetes Prevention Outcome Study.Lancet Diabetes Endocrinol. 2019;7(6):452-61. https://doi.org/10.1016/S2213-8587(19)30093-2
Guardado-Mendoza R, García-Magaña MA, Martínez-Navarro LJ,Macías-Cervantes HE, Aguilar-Guerrero R, Suárez-Pérez EL, et al. Effect oflinagliptin plus insulin in comparison to insulin alone on metabolic controland prognosis in hospitalized patients with SARS-CoV-2 infection. Sci Rep.2022;12:536. https://doi.org/10.1038/s41598-021-04511-1
Guardado-Mendoza R, Salazar-López SS, Álvarez-Canales M, Farfán-Vázquez D, Martínez-López YE, Jiménez-Ceja LM, et al. The combination oflinagliptin, metformin and lifestyle modification to prevent type 2 diabetes(PRELLIM). A randomized clinical trial. Metabolism. 2020;104:154054.https://doi.org/10.1016/j.metabol.2019.154054
Sandforth A, von Schwartzenberg R, Vazquez-Arreola E, Hanson RL, SancarG, Katzenstein S, et al. Mechanisms of weight loss-induced remission in peoplewith prediabetes: a post-hoc analysis of the randomised, controlled, multicentrePrediabetes Lifestyle Intervention Study (PLIS). Lancet Diabetes Endocrinol.2023;11(11):798-810. https://doi.org/10.1016/S2213-8587(23)00235-8
Vatcheva KP, Fisher-Hoch SP, Reininger BM, McCormick JB. Sex and agedifferences in prevalence and risk factors for prediabetes in Mexican-Americans. Diabetes Res Clin Pract. 2020;159:107950. https://doi.org/10.1016/j.diabres.2019.107950
Moradpour F, Rezei S, Piroozi B, Moradi G, Moradi Y, Piri N, et al.Prevalence of prediabetes, diabetes, diabetes awareness, treatment, and itssocioeconomic inequality in west of Iran. Sci Rep. 2022;12:17892. https://doi.org/10.1038/s41598-022-22779-9
Villanueva-Sosa LG, Cordero-Franco HF, Salinas-Martinez AM. Prevalenceof prediabetes based on fasting plasma glucose and glycosylatedhemoglobin in an at-risk Mexican population. Metab Syndr Relat Disord.2015;13(8):352-5. https://doi.org/10.1089/met.2015.0040
Xia M, Liu K, Feng J, Zheng Z, Xie X. Prevalence and risk factors oftype 2 diabetes and prediabetes among 53,288 middle-aged and elderlyadults in China: a cross-sectional study. Diabetes Metab Syndr Obes.2021;14:1975-85. https://doi.org/10.2147/DMSO.S305919
Akhtar S, Nasir JA, Ali A, Asghar M, Majeed R, Sarwar A. Prevalence of type-2 diabetes and prediabetes in Malaysia: A systematic review and meta-analysis.PLoS One. 2022;17:e0263139. https://doi.org/10.1371/journal.pone.0263139
Broz J, Malinovská J, Nunes K, Kucera K, Rožeková K, Žejglicová K, etal. Prevalence of diabetes and prediabetes and its risk factors in adultsaged 25-64 in the Czech Republic: A cross-sectional study. Diabetes ResClin Pract. 2020;170:108470. https://doi.org/10.1016/j.diabres.2020.108470
Guerrero-Romero F, Rodríguez-Morán M, Pérez-Fuentes R, Sánches-Guillén MC, González-Ortiz M, Martínez-Abundis E, et al. Prediabetesand its relationship with obesity in Mexican adults: The Mexican DiabetesPrevention (MexDiab) Study. Metab Syndr Relat Disord. 2008;6(1):15-23.https://doi.org/10.1089/met.2007.0020
Kumar A, Wong R, Ottenbacher KJ, Al Snih S. Prediabetes, undiagnoseddiabetes, and diabetes among Mexican adults: findings from the MexicanHealth and Aging Study. Ann Epidemiol. 2016;26(3):163-70. https://doi.org/10.1016/j.annepidem.2015.12.006
Menon VU, Kumar KV, Gilchrist A, Sugathan TN, Sundaram KR, NairV, et al. Prevalence of known and undetected diabetes and associated riskfactors in central Kerala--ADEPS. Diabetes Res Clin Pract. 2006;74(3):289-94. https://doi.org/10.1016/j.diabres.2006.03.025
Villalpando S, Shamah-Levy T, Rojas R, Aguilar-Salinas CA. Trendsfor type 2 diabetes and other cardiovascular risk factors in Mexicofrom 1993-2006. Salud Publica Mex. 2010;52(suppl 1):S72-9. https://doi.org/10.1590/s0036-36342010000700011
Vilchis-Flores LH, Barajas-Medina GA, Villa-Martínez AK, Salazar-LópezSS, Luna-Patiño GA, Quiroz-Hernández ME, et al. Pancreatic beta-celldysfunction in normoglycemic patients and risk factors. Acta Diabetol.2019;56:1305-14. https://doi.org/10.1007/s00592-019-01411-9
Barry E, Roberts S, Oke J, Vijayaraghavan S, Normansell R, GreenhalghT. Efficacy and effectiveness of screen and treat policies in preventionof type 2 diabetes: systematic review and meta-analysis of screeningtests and interventions. BMJ. 2017;356:i6538. https://doi.org/10.1136/bmj.i6538