2024, Número 1
<< Anterior Siguiente >>
Rev Biomed 2024; 35 (1)
Efecto de la canela y jengibre en la temperatura superficial supraclavicular y parámetros de salud en jóvenes
García-Torres E, Reyes-Meza V, Pérez-Flores GA
Idioma: Ingles.
Referencias bibliográficas: 39
Paginas: 28-35
Archivo PDF: 486.14 Kb.
RESUMEN
Introducción. El tejido adiposo pardo en humanos se localiza en
diferentes áreas del cuerpo, principalmente en el área supraclavicular y
su activación con diferentes moléculas termogénicas podría reflejarse
en este sitio. El tejido adiposo pardo activo podría ser una estrategia
contra la obesidad considerando su participación en el balance
energético.
Objetivo. Evaluar el efecto de la canela y el jengibre sobre la temperatura
cutánea supraclavicular y en parámetros de salud en jóvenes.
Material y métodos. Se llevó a cabo un estudio experimental con
36 adultos jóvenes que fueron asignados a uno de los tres grupos de
tratamiento: bebida de jengibre, bebida de canela y agua potable como
grupo placebo. La temperatura supraclavicular de la piel, la presión
arterial, la frecuencia cardíaca, el nivel de glucosa y los triglicéridos se
registraron antes y después de ingerir la bebida.
Resultados. Se observó un aumento en la temperatura supraclavicular
de la piel después de la ingesta de las bebidas de canela (0.62 °C),
jengibre (0.54 °C) y placebo (0.64 °C). En el grupo que ingirió jengibre,
también se observó una disminución de la glucosa (6.3 %), un aumento
de los triglicéridos (34.4 %) y una disminución en el ritmo cardiaco
(13.3 %), pero estas diferencias no fueron significativas en el grupo
que ingirió canela ni en el grupo placebo.
Conclusión. Nuestros resultados sugieren que la canela y el jengibre
tienen efectos termogénicos en el área supraclavicular en hombres
jóvenes.
REFERENCIAS (EN ESTE ARTÍCULO)
Astrup A, Breumand L, Toubro S. Pharmacologicaland clinical studies of ephedrine and other thermogenicagonists. Obes Res. 1995 Nov; 3:537–540.doi:10.1002/j.1550-8528.1995.tb00224.x
Robinson L, Ojha S, Symonds ME, Budge H. Body massindex as a determinant of brown adipose tissue functionin healthy children. J Pediatr. 2014 Feb; 164: 318–322.doi:10.1016/j.jpeds.2013.10.005
Sánchez-Delgado G, Martinez-Tellez B, Olza J, AguileraCM, Gil A, Ruiz JR. Role of exercise in the activationof brown adipose tissue. Ann Nutr Metab. 2015 Jul; 67:21–32. doi:10.1159/000437173
Kajimura S, Spiegelman BM, Seale P. Brown andbeige fat: physiological roles beyond heat generation.Cell Metab. 2015 Oct; 22(4): 546-59. doi:10.1016/j.cmet.2015.09.007
Chondronikola M, Sidossis LS. Brown and beige fat:from molecules to physiology. BBA - Molecular andCell Biology of Lipids. 2019 Jan; 1864(1): 91-103.doi:10.1016/j.bbalip.2018.05.014
Cypess AM, Weiner LS, Roberts-Toler C, Elía EF,Kessler SH, Kahn PA, et al. Activation of human brownadipose tissue by a β3-adrenergic receptor agonist.Cell Metab. 2015 Jan; 21(1): 33–38. doi: 10.1016/j.cmet.2014.12.009
Westerterp-Plantenga M, Diepvens K, Joosen AM,Bérubé-Parent S, Tremblay A. Metabolic effects ofspices, teas, and caffeine. Physiol Behav. 2006 Aug; 89:
85–91. doi:10.1016/j.physbeh.2006.01.0278. Tinsley GM, Urbina S, Mullins J, Outlaw J, HaywardS, Stone M, et al. Influence of a thermogenic dietarysupplement on safety markers, body composition,energy expenditure, muscular performance and hormoneconcentrations: a randomized, placebo-controlled,double-blind trial. J Sports Sci Med. 2017 Dec; 16: 459–467.
Saito M, Yoneshiro T, Matsushita M. Activation andrecruitment of brown adipose tissue by cold exposure andfood ingredients in humans. Best Practice & ResearchClinical Endocrinology & Metabolism. 2016 Aug; 30:537e547. doi:10.1016/j.beem.2016.08.003
Vogel RM, Joy JM, Falcone PH, Mosman MM, Kim MP,Moon JR. Consuming a multi-ingredient thermogenicsupplement for 28 days is apparently safe in healthyadults. Food Nutr Res. 2015 Jul; 59: 27999. doi:10.3402/fnr.v59.27999
Stohs SJ, Badmaev V. A review of natural stimulant andnon-stimulant thermogenic agents. Phytother Res. 2016Feb; 30: 732–740. doi:10.1002/ptr.5583
Ebrahimzadeh Attari V, Malek Mahdavi A, Javadivala Z,Mahluji S, Zununi Vahed S, Ostadrahimi A. A systematicreview of the anti-obesity and weight lowering effect ofginger (Zingiber officinale Roscoe) and its mechanismsof action. Phytother Res. 2018 Nov; 32: 577–585.doi:10.1002/ptr.5986
Mansour MS, Ni YM, Roberts AL, Kelleman M, RoyChoudhury A, St-Onge MP. Ginger consumptionenhances the thermic effect of food and promotesfeelings of satiety without affecting metabolic andhormonal parameters in overweight men: A pilot study.Metabolism. 2012 Oct; 61: 1347–1352. doi:10.1016/j.metabol.2012.03.016
Fujisawa F, Nadamoto T, Fushiki T. Effect of intake ofginger on peripheral body temperature. J Jpn Soc NutrFood Sci. 2005; 58: 3–9.
Mozaffari-Khosravi H, Talaei B, Jalali BA, NajarzadehA, Mozayan MR. The effect of ginger powdersupplementation on insulin resistance and glycemicindices in patients with type 2 diabetes: A randomized,double-blind, placebo-controlled trial. ComplementTher Med. 2014 Feb; 22: 9–16. doi:10.1016/j.ctim.2013.12.017
Attari VE, Ostadrahimi A, Jafarabadi MA, MehralizadehS, Mahluji S. Changes of serum adipocytokines and bodyweight following Zingiber officinale supplementation inobese women: a RCT. Eur J Nutr. 2016 Aug; 55: 2129–2136. doi.org/10.1007/s00394-015-1027-6
Sheng X, Zhang Y, Gong Z, Huang C, Zang YQ.Improved insulin resistance and lipid metabolism bycinnamon extract through activation of peroxisomeproliferator-activated receptors. PPAR Res. 2008 Nov;2008: 581348–9. doi:10.1155/2008/581348
Ranasinghe P, Jayawardena R, Pigera S, WathurapathaWS, Weeratunga HD, Premakumara GAS, et al.Evaluation of pharmacodynamic properties and safety ofCinnamomum zeylanicum (Ceylon cinnamon) in healthyadults: a phase I clinical trial. BBC Complement AlternMed. 2017 Dec; 17: 550. doi:10.1186/s12906-017-2067-7
Shen Y, Honma N, Kobayashi K, Jia LN, Hosono T,Shindo K, et al. Cinnamon extract enhances glucoseuptake in 3T3-L1 adipocytes and C2C12 myocytes byinducing LKB1-AMP-activated protein kinase signaling.PLoS One. 2014 Feb; 9: e87894. doi:10.1371/journal.pone.0087894
Kwan HY, Wu J, Su T, Chao XJ, Liu B, Fu X, et al.Cinnamon induces browning in subcutaneous adipocytes.Sci Rep. 2017 May; 7: 2447. doi:10.1038/s41598-017-02263-5
Borzoei A, Rafraf M, Asghari-Jafarabadi M. Cinnamonimproves metabolic factors without detectable effects onadiponectin in women with polycystic ovary síndrome.Asia Pac J Clin Nutr. 2018 May; 27(3): 556-563.doi:10.6133/apjcn.062017.13
Solomon TP, Blannin AK. Effects of short-term cinnamoningestion on in vivo glucose tolerance. Diabetes ObesMetab. 2007 Feb; 9: 895–901. doi:10.1111/j.1463-1326.2006.00694.x
Wang JG, Anderson RA, Graham GM, Chu MC, SauerMV, Guarnaccia MM, et al. The effect of cinnamonextract on insulin resistance parameters in polycysticovary syndrome: a pilot study. Fertil Steril. 2007 Jul; 88:
240–243. doi:10.1016/j.fertnstert.2006.11.08224. Khan A, Safdar M, Khan MMA, Khattak KN, AndersonRA. Cinnamon improves glucose and lipids of peoplewith type 2 diabetes. Diabetes Care. 2003 Dec; 26:3215–8. doi:10.2337/diacare.26.12.3215
Ziegenfuss TN, Hofheins JE, Mendel RW, Landis J,Anderson RA. Effects of a water-soluble cinnamonextract on body composition and features of the metabolicsyndrome in pre-diabetic men and women. J Int SocSports Nutr. 2006 May; 3: 45–53. doi.org/10.1186/1550-2783-3-2-45
Hasanein MA, Gawad SHA, El-Megeid AAA. Effectof water extract prepared from green tea, black tea andcinnamon on obese rats suffering from diabetes. WorldAppl Sci J. 2012; 20: 976–987. doi: 10.5829/idosi.wasj.2012.20.07.2834
van Marken Lichtenbelt WD, Vanhommerig JW,Smulders NM, Drossaerts JM, Kemerink GJ, BouvyND, et al. Cold-activated brown adipose tissue in healthymen. N Engl J Med. 2009 Apr 9;360(15):1500-8. doi:10.1056/NEJMoa0808718
Saito M, Matsushita M, Yoneshiro T, Okamatsu-OguraY. Brown adipose tissue, diet-induced thermogenesis,and thermogenic food ingredients: from mice to men.Front Endocrinol. 2020 Apr 21;11:222. doi:10.3389/fendo.2020.00222
SaitoM, Yoneshiro T. Capsinoids and related foodingredients activating brown fat thermogenesis andreducing body fat in humans. Curr Opin Lipidol. 2013 Feb1;24(1):71–77. doi:10.1097/MOL.0b013e32835a4f40
Iwasaki Y, Tanabe M, Kobata K, Watanabe T. TRPA1agonists--allyl isothiocyanate and cinnamaldehyde--induce adrenaline secretion. Biosci Biotechnol Biochem.2008 Jun; 72: 2608–2614. doi:10.1271/bbb.80289
Camacho S, Michlig S, de Senarclens-Bezençon C,Meylan J, Meystre J, Pezzoli M, et al. Anti-obesityand anti-hyperglycemic effects of cinnamaldehyde viaaltered ghrelin secretion and functional impact on foodintake and gastric emptying. Sci Rep. 2015 Jan; 21:7919. doi:10.1038/srep07919
Iwasaki Y, Morita A, Iwasawa T, Kobata K, Sekiwa Y,Morimitsu Y, et al. A nonpungent component of steamedginger--[10]-shogaol--increases adrenaline secretion viathe activation of TRPV1. Nutr Neurosci. 2006 Aug; 9:169–78. doi:10.1080/110284150600955164
Miyamoto M, Matsuzaki K, Katakura M, Hara T, TanabeY, Shido O. Oral intake of encapsulated dried ginger rootpowder hardly affects human thermoregulatory function,but appears to facilitate fat utilization. Int J Biometeorol.2015 Jan; 59: 1461–1474. doi:10.1007/s00484-015-0957-2
Sugimoto K, Takeuchi H, Nakagawa K, MatsuokaY. Hyperthermic effect of ginger (Zingiberofficinale) extract-containing beverage on peripheralskin surface temperature in women. Evid BasedComplement Alternat Med. 2018 Oct; 2018: 3207623.doi:10.1155/2018/3207623
Bartelt A, Bruns OT, Reimer R, Hohenberg H, IttrichH, Peldschus K, Kaul MG, Tromsdorf UI, Weller H,Waurisch C, Eychmüller A. Brown adipose tissueactivity controls triglyceride clearance. Nat Med. 2011Feb;17(2):200-5. doi:10.1038/nm.2297
Nedergaard J, Bengtsson T, Cannon B. New powersof brown fat: fighting the metabolic syndrome. CellMetab. 2011 Mar 2;13(3):238-40. doi:10.1016/j.cmet.2011.02.009
Brandão BB, Poojari A, Rabiee A. Thermogenic fat:development, physiological function, and therapeuticpotential. Int J Mol Sci. 2021 May 31;22(11):5906.doi:10.3390/ijms22115906
Anderson RA, Zhan Z, Luo R, Guo X, Guo Q, ZhouJ, et al. Cinnamon extract lowers glucose, insulin andcholesterol in people with elevated serum glucose.J Tradit Complement Med. 2016 Oct; 6: 332–336.doi:10.1016/j.jtcme.2015.03.005
Cannon B, Nedergaard J. Metabolic consequences ofthe presence or absence of the thermogenic capacity ofbrown adipose tissue in mice (and probably in humans).Int J Obesity. 2010 Oct; 34: S7–S16. doi:10.1038/ijo.2010.177