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2022, Número 1

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Rev Cuba Endoc 2022; 33 (1)


Factores clínicos y ambientales asociados a la tiroiditis de Hashimoto

Parlá SJ, González HO, de la Rosa SJJ, Yanes QM, Cubas DI, Pérez GC, Marrero MT

Idioma: Español
Referencias bibliográficas: 52
Paginas:
Archivo PDF: 319.78 Kb.


RESUMEN

Introducción: La tiroiditis de Hashimoto es una enfermedad tiroidea autoinmune poligénica y multifactorial resultante de una interacción compleja de factores genéticos y ambientales.
Objetivo: Determinar la posible asociación de los factores clínicos y ambientales con los niveles de anticuerpos antitiroideos y las pruebas de función tiroidea en la tiroiditis de Hashimoto.
Métodos: Estudio observacional, descriptivo y transversal con 120 personas con diagnóstico de tiroiditis de Hashimoto. Variables estudiadas: edad, sexo, color de la piel, estado nutricional, paridad, hábito de fumar, consumo de alcohol, preparados estrogénicos, antecedentes familiares de enfermedad autoinmune tiroidea y personales de otras enfermedades autoinmunes. Se realizaron determinaciones de anticuerpos AbTPO, TSH, T3 y T4.
Resultados: Predominio del sexo femenino (92,5 %), de pacientes de piel blanca (50,8 %) y con sobrepeso corporal (40 %). El 73 % no consumían preparados estrogénicos. El 20 % tenían antecedentes familiares de enfermedad tiroidea y personales de diabetes mellitus tipo 1 (7,5 %). La media del anticuerpo en pacientes con antecedentes de infecciones virales fue superior a los que no tuvieron este antecedente (732,6 vs. 624,6). El resto de las variables no mostraron diferencias entre las medias del anticuerpo. Ninguno de los factores estudiados mostró asociación con el estado de la función tiroidea. (p>0,05).
Conclusiones: No existió asociación entre los factores clínicos y ambientales en relación a los niveles de Ac TPO y el estado de la función tiroidea, con predominio del hipotiroidismo manifiesto al diagnóstico de la TH.


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