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2006, Número S4

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Arch Cardiol Mex 2006; 76 (S4)


Los segmentos cardíacos primitivos, su implicación en la cardiogénesis normal aplicada a la cardiología pediátrica

Salazar GM, Sánchez GC, Contreras RA, Carrillo ÁBA, Revilla MMC, Palomino GMA

Idioma: Español
Referencias bibliográficas: 62
Paginas: 46-57
Archivo PDF: 189.75 Kb.


RESUMEN

El gran desarrollo de la imagenología diagnóstica en la cardiología pediátrica ha exigido un conocimiento preciso de la anatomía alterada de los corazones con cardiopatía congénita. De esta manera, la información sobre la embriología cardíaca, en los aspectos morfológicos y moleculares constituye un fundamento para comprender la anatomía de los corazones malformados. Con base en estos hechos, en este trabajo se revisa la cardiogénesis normal, integrando los nuevos hallazgos logrados experimentalmente en el embrión de pollo con los conocimientos clásicos descriptivos en humanos. Se especifica la edad en que surgen los primordios que forman las cavidades definitivas, sus cambios de posición y relaciones entre sí, desde que aparecen hasta que se inicia la tabicación cardíaca. También se hace una correlación entre la embriología normal del corazón y los posibles mecanismos que producen las cardiopatías congénitas, así como la participación de genes específicos. Esta información además de facilitar el diagnóstico de las cardiopatías congénitas ayuda en la discusión de su posible embriogénesis, así como los genes que la regulan, conocimiento indispensable en la planeación de estrategias para evitar estas enfermedades.


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