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Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán

2023, Número 2

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Rev Biomed 2023; 34 (2)


Diabesidad en los mayas de Yucatán: Metabolismo, genotipo, fenotipo y consideraciones del ambiente sociocultural y desarrollo temprano

Lara-Riegos J, Azcorra-Pérez HS

Idioma: Ingles.
Referencias bibliográficas: 63
Paginas: 168-178
Archivo PDF: 188.93 Kb.


RESUMEN

La diabesidad es un neologismo que nosotros utilizamos para describir a la diabetes tipo 2 en un contexto de obesidad. En esta revisión descriptiva, nuestro objetivo fue analizar el fenómeno de la diabesidad contextualizada en la población maya yucateca, dada la importancia demográfica de esta etnia en el país y por la alta prevalencia de diabetes y obesidad. Primero describimos los rasgos fenotípicos y genotípicos asociados con la diabesidad; también discutimos el papel de los factores socioculturales que han incidido en el patrón alimentario de los mayas y la evidencia disponible respecto a las características fenotípicas adquiridas durante las primeras etapas de desarrollo y sus posibles repercusiones en el metabolismo y la presencia de obesidad y diabetes. Finalmente, proponemos que la falla en la secreción de insulina y la glucolipotoxicidad son factores comunes y un posible factor unificador de la diabesidad entre la población maya. Para ello recurrimos a fuentes primarias de información, incluyendo artículos originales de investigación y capítulos de libros editados sobre diabesidad y ensayos sociohistóricos sobre la población maya.


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