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2023, Número 3

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Acta Pediatr Mex 2023; 44 (3)


Epidemiología, Manifestaciones Clínicas y Fisiopatología del Síndrome Inflamatorio Sistémico en la Infancia

Rodríguez-Lozano AL, Toledo-Salinas CC, Bayardo-Gutiérrez B, Nájera-Velázquez RG

Idioma: Español
Referencias bibliográficas: 95
Paginas: 221-241
Archivo PDF: 397.50 Kb.


RESUMEN

El síndrome multisistémico inflamatorio pediátrico se ha reconocido como una condición emergente, un nuevo espectro de enfermedad pediátrica asociada a la infección por SARS-CoV-2. Este síndrome fue identificado inicialmente en Europa y se denominó PIMS-TS (Pediatric Inflammatory Multisystem Syndrome – Temporally associated with SAR-CoV-2) posteriormente en los Estados Unidos de América, se designó como MIS-C (Multisystem Inflammatory Syndrome in Children), cuando en mayo de 2020 la OMS acuñó el término. La incidencia de MIS-C en pacientes menores de 21 años infectados con SARS-CoV-2 es de 5.1 por 1, 000,000 personasmes [IC 95% 4.5 a 5-8], y es mayor en los pacientes afroamericanos e hispanos o latinos con respecto a los caucásicos. En este artículo resumiremos los principales hallazgos en cuanto a la epidemiología, las manifestaciones clínicas, la fisiopatología y finalmente presentaremos información acerca de si MIS-C pertenece al espectro de la enfermedad de Kawasaki.


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