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Instituto Nacional de Salud Pública

2023, Número 2

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salud publica mex 2023; 65 (2)


Procesos celulares modificados en Aedes aegypti infectados con Wolbachia y la susceptibilidad al virus dengue

López-Ordóñez T, Díaz-Rodarte KI, Torres-Monzón JA, Casas-Martínez M, Danis-Lozano R, Mosso-González C

Idioma: Español
Referencias bibliográficas: 46
Paginas: 136-143
Archivo PDF: 291.73 Kb.


RESUMEN

Objetivo. Analizar la expresión diferencial de proteínas de Aedes aegypti infectados con Wolbachia y su asociación con el ciclo viral del virus dengue (DENV). Material y métodos. Se revisó una base de datos de proteínas de Ae. aegypti infectados y no infectados con Wolbachia, cepa wMel y se buscaron estas en revistas indizadas, que hablaran de la proteína y el ciclo viral de DENV. Resultados. La expresión diferencial de proteínas de los mosquitos durante la infección con Wolbachia intervienen en los procesos de entrada, replicación y salida del DENV. Conclusiones. Existen cambios en la expresión de proteínas de células infectadas con Wolbachia, que son necesarias para el ciclo de replicación de DENV, explicando porque algunos mosquitos infectados con Wolbachia son refractarios a la infección por DENV.


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