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2022, Número Esp

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Rev Med UAS 2022; 12 (Esp)


Cáncer colorrectal de inicio temprano

Trujillo-Rojas MÁ, Beltrán-Ontiveros SA, Zavala-Castillo JM, Sosa-Chombo MF, Verdugo-Rosas A, Rochín-Terán JL, Bolívar-Rodríguez MA, Mora-Palazuelos CE, López-Manjarrez G, Moreno-Ortiz JM

Idioma: Español
Referencias bibliográficas: 52
Paginas: 23-32
Archivo PDF: 174.71 Kb.


RESUMEN

Las tasas de muerte y aparición de CCR se incrementan rápidamente después de los 50 años. Sin embargo, en los últimos años la incidencia de CCR en individuos de una edad menor de 50 (cáncer colorrectal de inicio temprano) se ha incrementado dramáticamente. Se desconocen las causas de este fenómeno. Aunque los síndromes de cáncer hereditario y los antecedentes familiares de CCR predisponen y explican algunos de los casos de inicio temprano, la mayoría de estos surgen esporádicamente, los cuales muy probablemente están ligados a factores de riesgo de estilo de vida y ambientales. Los casos en jóvenes poseen características clínico-patológicas y moleculares particulares. Suelen presentar características tumorales agresivas y un estado avanzado de la enfermedad al diagnóstico. Por lo anterior, se requieren más estudios sobre la patogénesis de esta enfermedad además de estudios sobre posibles factores de riesgo específicos para este subgrupo de pacientes.


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