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Órgano Oficial del Colegio Mexicano de Alergia, Asma e Inmunología Pediátrica y de la Asociación Latinoamericana de Pediatría

2006, Número 2

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Alerg Asma Inmunol Pediatr 2006; 15 (2)


Marcha alérgica: el camino de la atopia

Aviña FJA, Castañeda GD

Idioma: Español
Referencias bibliográficas: 65
Paginas: 50-56
Archivo PDF: 106.71 Kb.


RESUMEN

La marcha alérgica es el camino clínico que recorre el enfermo atópico durante la evolución cronológica de sus enfermedades alérgicas; se presenta en aquellos individuos que teniendo una base genética de herencia atópica, se ponen en contacto con sustancias externas que actúan como alergenos y les desencadenan una respuesta inmunológica alterada con activación de la línea celular de linfocitos helper Th2, produciéndose citocinas inflamatorias que estimularán una respuesta humoral con altos niveles de anticuerpos específicos de inmunoglobulina IgE, perpetuando las manifestaciones clínicas de inflamación crónica y recurrente en los sitios de contacto con los alergenos como pueden ser: tubo digestivo, piel y vías respiratorias. Se describen los niveles de prevención para evitar que los pacientes atópicos recorran este camino alérgico.


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