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2000, Número 2

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Rev Mex Patol Clin Med Lab 2000; 47 (2)


Apoptosis en protozoarios y en la célula huésped inducida por protozoarios

Fernández-Presas AM

Idioma: Español
Referencias bibliográficas: 68
Paginas: 84-93
Archivo PDF: 110.07 Kb.


RESUMEN

La apoptosis es una forma de muerte celular programada que ha sido descrita como un mecanismo esencial en la organogénesis normal y en el desarrollo tisular, así como en funciones celulares propias de sistemas de renovación celular en organismos adultos. La apoptosis preserva la homeostasis, manteniendo un estricto balance entre la proliferación y la muerte celular. Se considera un fenómeno biológico generalizado, encontrado tanto en organismos multicelulares como en unicelulares; los mecanismos de inducción de la apoptosis, los patrones morfológicos y los sistemas reguladores son básicamente los mismos en estos organismos. Los protozoarios, además de sufrirla, son capaces de inducir o prevenir la apoptosis en las células de sus huéspedes, dependiendo de lo que más les convenga. Es interesante que los mecanismos de regulación y la maquinaria de muerte celular se hayan conservado evolutivamente. Ésta es una revisión del fenómeno de apoptosis en protozoarios y de apoptosis inducida en células del huésped que aloja a estos parásitos.


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