Tabla 1: Comparación de variables entre pacientes que desarrollaron y no desarrollaron lesión renal aguda (LRA). |
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Variable |
Sin LRA N = 155 |
LRA N = 86 |
OR (IC 95%) |
p |
Edad, (meses) mediana (RIC) |
26 (6-144) |
12 (4-87) |
— |
0.12 |
Sexo, n (%) |
0.75 (0.42-1.2) |
0.30 |
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Masculino |
104 (67.1) |
52 (60.5) |
— |
— |
Femenino |
51 (32.9) |
34 (39.5) |
— |
— |
Peso [kg], mediana (RIC) |
12 (6.7-45) |
10 (5-25) |
— |
0.04‡ |
Diagnóstico, n (%) |
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Sepsis |
38 (24.5) |
29 (33.7) |
1.5 (0.8-2.7) |
0.12 |
Respiratorio |
54 (34.8) |
26 (30.2) |
0.81 (0.46-1.4) |
0.46 |
Neurológico |
41 (26.5) |
12 (14.0) |
0.4 (0.2-0.9) |
0.02* |
Quirúrgico |
54 (34.8) |
18 (20.9) |
0.5 (0.3-0.9) |
0.02* |
PRISM III, mediana (RIC) |
5 (2-10) |
8 (5.0-12.0) |
— |
0.003‡ |
PRISM ≥ 9, n (%) |
46 (29.7) |
38 (44.2) |
1.9 (1.1-3.2) |
0.02* |
Cl-mEq/L, mediana RIC |
103 (100-105) |
105 (100-107) |
— |
0.67 |
Hipercloremia, n (%) |
16 (10.3) |
14 (16.3) |
1.7 (0.7-3.6) |
0.18 |
Na+ mEq/L, mediana RIC |
140 (137-142) |
140 (139-147) |
— |
0.05 |
Hipernatremia, n (%) |
19 (12.3) |
26 (30.2) |
3.1 (1.6-6.0) |
0.001* |
Bolo(s) de SS 0.9%, n (%) |
90 (58.1) |
64 (74.4) |
3.0 (1.5-6.0) |
0.011* |
SCL ≥ 10%, n (%) |
52 (33.5) |
45 (52.3) |
2.2 (1.2-3.7) |
0.004 |
Días ventilación mecánica, media ± DT |
8.8 ± 11.9 |
10.4 ± 12.3 |
— |
0.31 |
Ventilación mecánica ≥ 6 días, n (%) |
66 (42.6) |
42 (42.8) |
1.2 (0.7-2.1) |
0.35 |
Acidosis metabólica, n (%) |
11 (7.1) |
6 (7.0) |
0.9 (0.3-2.7) |
0.97 |
OR = Odds ratio. IC 95% = intervalo de confianza a 95%. RIC = rango intercuartílico. PRISM = riesgo de mortalidad pediátrica. SS = solución salina. SCL = sobrecarga de líquidos. DT = desviación típica. * χ2 de Pearson. ‡ U de Mann Whitney. |