Table 2: Recommended dosing of elexacaftor/tezacaftor/ivacaftor for cystic fibrosis patients according to age and weight.

Age

Morning dose

Evening dose

2 to < 6

years

< 14 kg

1 white and blue packet

of elexacaftor 80 mg/tezacaftor

40 mg/ivacaftor 60 mg

≥ 14 kg

1 white and orange packet of

elexacaftor 100 mg/tezacaftor

50 mg/ivacaftor 75 mg

1 white and green

packet of ivacaftor 59.5 mg

1 white and

pink packet of

ivacaftor 75 mg

6 to < 12

years

< 30 kg

2 light orange tablets of

elexacaftor 50 mg/tezacaftor

25 mg/ivacaftor 37.5 mg

≥ 30 kg

2 orange tablets of elexacaftor

100 mg/tezacaftor 50 mg/

ivacaftor 75 mg

1 light blue tablet

of ivacaftor

75 mg

1 light blue tablet

of ivacaftor

150 mg

12 years

and older

2 orange tablets of elexacaftor

100 mg/tezacaftor 50 mg/

ivacaftor 75 mg

1 light blue tablet

of ivacaftor

150 mg