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Table 3: Changes in anthropometrics, functional aerobic capacity, dyspnea anxiety/depression and health-related quality of life in patients with other DILDs (N = 32). |
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|
Variables |
Other DILDs, mean ± SD |
p |
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|
Physical exercise and education |
Mean differences ± SE |
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|
Initial |
Final |
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|
Weight (kg) |
67.84 ± 14.26 |
68.66 ± 13.72 |
-0.82 ± 0.48 |
0.098 |
|
BMI (kg/m2) |
31.16 ± 5.34 |
31.46 ± 5.32 |
-0.29 ± 0.17 |
0.102 |
|
Distance travelled 6MWT (m) |
353.0 ± 121.13 |
415.0 ± 107.91 |
-62.00 ± 8.19 |
0.000 |
|
SpO2 at rest (%) |
95.22 ± 2.72 |
95.31 ± 2.73 |
-0.09 ± 0.69 |
0.893 |
|
SpO2 final (%) |
86.94 ± 6.8 |
86.91 ± 5.59 |
0.031 ± 0.88 |
0.972 |
|
Desaturation percentage |
8.28 ± 5.93 |
8.38 ± 5.24 |
-0.09 ± 0.79 |
0.906 |
|
VO2e (mL/kg/min) |
9.17 ± 2.12 |
10.43 ± 1.79 |
-1.26 ± 0.23 |
0.000 |
|
MRC |
2.38 ± 1.07 |
1.78 ± 1.26 |
0.59 ± 0.21 |
0.007 |
|
HAD anxiety |
5.38 ± 3.79 |
3.81 ± 3.33 |
1.56 ± 0.46 |
0.002 |
|
HAD depression |
5.25 ± 3.52 |
4.34 ± 4.41 |
0.91 ± 0.69 |
0.198 |
|
SGRQ symptoms |
51.97 ± 18.38 |
38.28 ± 17.40 |
13.69 ± 3.12 |
0.000 |
|
SGRQ activities |
68.31 ± 18.30 |
57.25 ± 22.67 |
11.06 ± 3.24 |
0.002 |
|
SGRQ impact |
44.59 ± 19.79 |
35.84 ± 20.26 |
8.75 ± 3.81 |
0.029 |
|
SGRQ total |
54.78 ± 17.58 |
44.53 ± 19.11 |
10.25 ± 3.04 |
0.002 |
|
DILD = diffuse interstitial lung disease. SD = standard deviation. SE = standard error. BMI = body mass index. 6MWT = 6 minute walk test. SpO2 = partial oxygen saturation. VO2e = estimated oxygen consumption. MRC = medical research council. HAD = hospital anxiety and depression scale. SGRQ = Saint George’s respiratory questionnaire. |
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