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Table 2: Changes in anthropometrics, functional aerobic capacity, dyspnea anxiety/depression and health-related quality of life in patients with IPF (N = 29). |
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|
Variables |
IPF, mean ± SD |
p |
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|
Physical exercise and education |
Mean differences ± SE |
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|
Initial |
Final |
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|
Weight (kg) |
67.03 ± 13.24 |
67.41 ± 13.78 |
-0.37 ± 0.49 |
0.434 |
|
BMI (kg/m2) |
26.23 ± 4.47 |
26.36 ± 4.6 |
-0.13 ± 0.17 |
0.459 |
|
Distance travelled 6MWT (m) |
371.79 ± 121.39 |
435.38 ± 109.75 |
-63.59 ± 12.67 |
0.000 |
|
SpO2 at rest (%) |
95.90 ± 2.70 |
95.62 ± 2.61 |
-0.28 ± 0.37 |
0.463 |
|
SpO2 final (%) |
88.86 ± 8.85 |
89.10 ± 5.70 |
0.24 ± 0.74 |
0.747 |
|
Desaturation percentage |
7.03 ± 4.99 |
6.52 ± 5.03 |
-0.51 ± 0.68 |
0.452 |
|
VO2e (mL/kg/min) |
9.47 ± 2.16 |
10.77 ± 1.82 |
-1.31 ± 0.29 |
0.000 |
|
MRC |
2.10 ± 1.01 |
1.10 ± 1.08 |
1.0 ± 0.15 |
0.000 |
|
HAD anxiety |
6.31 ± 5.11 |
3.83 ± 3.37 |
2.48 ± 0.65 |
0.001 |
|
HAD depression |
5.52 ± 4.09 |
3.83 ± 2.98 |
1.69 ± 0.59 |
0.008 |
|
SGRQ symptoms |
50.90 ± 20.23 |
36.00 ± 17.68 |
14.90 ± 3.06 |
0.000 |
|
SGRQ activities |
61.83 ± 20.99 |
48.41 ± 28.99 |
13.41 ± 4.61 |
0.007 |
|
SGRQ impact |
40.86 ± 22.18 |
24.41 ± 16.77 |
16.45 ± 2.59 |
0.000 |
|
SGRQ total |
50.14 ± 18.90 |
34.00 ± 17.40 |
16.14 ± 2.22 |
0.000 |
|
IPF = idiopathic pulmonary fibrosis. SD = standard deviation. SE = standard error. BMI = body mass index. 6MWT = 6 minute walk test. SpO2 = partial oxygen saturation. VO2e = estimated oxygen consumption. MRC = Medical Research Council. HAD = hospital anxiety and depression scale. SGRQ = Saint George’s respiratory questionnaire. |
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