|
Table 1: Histopathologic differences between the main posterior mediastinal tumors. |
||
|
|
Neurofibroma |
Schwannoma |
|
Cytology |
|
|
|
Size of the nucleus |
+ |
++ |
|
Nuclear hyperchromasia |
+ |
++ |
|
Wavy nuclei |
+++ |
+ |
|
Histology |
|
|
|
«Shredded carrot»-type collagen |
+++ |
-/+ |
|
Capsule |
- |
+++ |
|
Hyalinized vessels |
-/+ |
+++ |
|
Fascicular growth pattern |
-/+ |
++ |
|
Mitotic activity |
-/+ |
-/+ |
|
Necrosis |
- |
-/+ |
|
Immunohistochemistry |
|
|
|
S100 |
++/+++ |
+++ |
|
Collagen IV |
++/+++ |
+++ |
|
EMA |
+ |
- |
|
CD34 |
+++ |
+++ |
|
Podoplanin |
+ |
++ |
|
Calretinin |
+ |
+++ |
|
Sox 10 |
+++ |
+++ |
|
EMA = epithelial membrane antigen. |
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