Table 2: Main characteristics of the study population.

 

BPD Severity

SD

Mild

n (%)

Moderate

n (%)

Severe

n (%)

p

Variables

3

71 (18.39)

182 (47.15)

130 (33.68)

NA

Maternal variables

Sex

Female

Male

1

 

26 (36.62)

44 (61.97)

 

79 (43.41)

103 (56.59)

 

55 (42.31)

75 (57.69)

 

 

0.153

Gestational age

Median and range (weeks)

Range

 

 

31.0

29-35

 

31.4

28-34

 

31.2

28-34

 

0.861

Birth weight

Median (g)

Range

 

 

1,500

1,030-2,200

 

1,300

1,000-2,100

 

1,305

1,050-2,050

 

0.597

Days with O2

Median (days)

Range

 

 

40

30-57

 

107

63-210

 

180

96-370

 

0.001*

Mechanical ventilation days

Median (days)

Range

36

 

12

6-22

 

20

10-30

 

54

49-59

 

0.001*

Surfactant

Yes

 

 

17 (23.94)

 

49 (26.92)

 

43 (33.08)

 

NC

Egress with O2

Yes

 

 

18 (25.35)

 

118 (64.84)

 

93 (71.54)

 

0.000*

Prenatal history

Chorioamnioitis

Yes

 

 

0 (0)

 

3 (1.65)

 

2 (1.54)

 

0.717

Intraventricular hemorrhage

Yes

 

 

9 (12.68)

 

31 (17.03)

 

27 (20.77)

 

0.344

Persistent ductus arteriosus

Yes

 

 

10 (14.08)

 

33 (18.13)

 

33 (25.38)

 

0.115

Enterocolitis

Yes

 

 

4 (5.63)

 

20 (10.99)

 

13 (10.00)

 

0.466

Perinatal asphyxia

Yes

 

 

17 (23.94)

 

44 (24.18)

 

37 (28.46)

 

0.577

Malnutrition at birth

Yes

 

 

66 (92.96)

 

165 (90.66)

 

122 (93.85)

 

0.285

Maternal background

 

 

 

 

 

Maternal age (years)

< 20

20-39

> 40

 

 

10 (14.08)

58 (81.69)

3 (4.23)

 

28 (15.38)

141 (77.47)

13 (7.14)

 

13 (10.00)

106 (81.54)

11 (8.46)

0.574

Maternal schooling

Primary

High school

Technical

University

Does not read or write

 

 

31 (43.66)

28 (39.44)

2 (3)

7 (10)

3 (4)

 

94 (51.65)

68 (37.36)

4 (2)

16 (9)

0.00 (0.00)

 

57 (43.85)

52 (40.00)

4 (3.08)

14 (10.8)

3 (2.31)

0.39

Cesarean section

Yes

 

 

54 (76.06)

 

133 (73.08)

 

95 (73.08)

 

0.876

Multiple pregnancy

Yes

 

 

3 (4.23)

 

5 (2.75)

 

5 (3.85)

 

0.807

Premature rupture

of membranes

Yes

 

 

 

19 (26.76)

 

 

44 (24.18)

 

 

40 (30.77)

 

 

0.432

Gestational hypertension

Yes

 

 

12 (16.9)

 

29 (15.93)

 

19 (14.62)

 

0.905

Family and environmental background

Passive smoking

Yes

 

 

10 (14.08)

 

26 (14.29)

 

12 (9.23)

 

0.493

Zoonoses

Yes

 

 

22 (30.99)

 

48 (26.37)

 

26 (20.00)

 

0.338

Wood smoke

Yes

 

 

4 (5.63)

 

4 (2.2)

 

4 (3.08)

 

0.393

Family history of asthma

Yes

 

 

5 (7.04)

 

7 (3.85)

 

9 (6.92)

 

0.462

* Statistically significant.

BPD = bronchopulmonary dysplasia.