Table 1: Summary of publications regarding the association between psychological factors and pulmonary obstructive chronic disease.

Outcome measures / Reference

Odds ratio - risk ratio - adjusted odds ratio - hazard ratio

Other factors found

Depression and emergency hospital admissions12

Depression and attendances at emergency departments

OR = 2.63; 95% CI (1.48-4.66)

 

OR = 2.78; 95% CI (1.55-4.99)

Even mild symptoms and moderate to severe symptoms of depression increase the risk of use of urgent care, these findings are independent of severity of disease and comorbidity of other chronic physical conditions

COPD and the likelihood
of suicide
13

OR = 1.90; 95% CI (1.27-2.48)

Similarly, risk factors associated with suicide, such as mental disorders, are underdiagnosed and undertreated

Comorbid depression and risk of mortality14

RR = 1.83; 95% CI (1.00-3.36).

COPD increases the risk of developing depression (RR = 1.69; 95% CI 1.45-1.96)

Bipolar disorder and COPD15

Schizophrenia and COPD16

OR 1.55; 95% CI (1.45-1.65)

OR 1.57; 95% CI (1.43-1.72)

The most important confounding factor the contribution of which must be evaluated to clarify the nature of the association between COPD and major mental illness is the smoking

Stress with acute care use in COPD

AOR = 2.51; 95% CI (1.06-5.98)

The high stress group had a 2.5-fold increased adjusted odds of acute care use compared to the low stress group

Physical activity-depression in COPD17

PA-anxiety in COPD

HR = 0.85; 95% CI (0.75-0.95)

 

HR = 0.89; 95% CI (0.79-1.00)

The study found more physically active patients [with higher PA levels equivalent to 2.5 metabolic equivalent tasks (METs), e.g., those who report walking outside vs. those who do not] had 15% and 11% lower risks of developing depression and anxiety, respectively, compared to physically inactive patients

OR = Odds ratio,

RR = risk ratio,

AOR = adjusted odds ratio,

HR = hazard ratio,

COPD = pulmonary obstructive chronic disease,

PA = physical activity,

CI = confidence intervals.