Tabla 1: Hallazgos hemodinámicos. |
|||||||||||||
Parámetro |
Grupo de estudio |
Tiempos de evolución (minutos) |
|||||||||||
|
|
0 |
15 |
30 |
45 |
60 |
75 |
90 |
105 |
120 |
135 |
150 |
165 |
PVRi PVRi din/sec/cm-5 |
Control Grupo I |
224.6 ± 91.3 |
227.1 ± 118.3 |
183.8 ± 67.8 |
193.6 ± 111.8 |
174.5 ± 59.1 |
188.5 ± 88.6 |
183.3 ± 63.1 |
221 ± 93 |
234.8 ± 114.4 |
229.3 ± 71.7 |
234 ± 94.8 |
246.1 ± 86.5 |
AO Grupo II |
275.6 ± 100.9 |
598.5 ± 288.6* |
441.1 ± 17* |
421.8* ± 201.7 |
471.3 ± 250.7* |
399.3 ± 239.7 |
366.8 ± 147 |
450.1 ± 155.1* |
395 ± 96.7 |
380.6 ± 156.7 |
482.1 ± 280.6 |
419.5 ± 165.5 |
|
L-arginina Grupo III |
189 ± 52.54 |
431 ± 85.32 |
344.2 ± 113.32 |
392 ± 201.85 |
365.8 ± 120.65 |
279.6 ± 98.8 |
267.6 ± 114.07 |
233 ± 127.03 |
276 ± 164.52 |
236.4 ± 106.75 |
243 ± 98.54 |
252.4 ± 101.93 |
|
SVRi SVRi din/sec/cm-5 |
Control Grupo I |
1,426.8 ± 347.8 |
1,425.5 ± 249.4 |
1,197.5 ± 206.3 |
1,264.3 ± 288.6 |
1,379.0 ± 183.6 |
1,319.8 ± 266.8 |
1,516.8 ± 337.9 |
1,596.8 ± 311.1 |
1,794 ± 286.1 |
1,789 ± 287.9 |
1,962.5 ± 375.9 |
1,904.1 ± 342.3 |
AO Grupo II |
3,310.8 ± 494.0* |
4,356 ± 814.9* |
3,663.1 ± 647.7* |
3,504 ± 687.8* |
3,011.6 ± 632.1* |
2,785.1 ± 567.4* |
2,805.8 ± 649.6 |
3,075.3 ± 822 |
2,468.3 ± 537.2 |
2,512.6 ± 500.9 |
2,489.8 ± 483.4 |
2,071.1 ± 399.3 |
|
L-arginina Grupo III |
1,891.4 ± 133.3 |
2,978.8 ± 74.3* |
3,033 ± 718.4 |
2,805.2 ± 501.1* |
2,788.8 ± 392.2* |
2,312.6 ± 242.3 |
2,136.6 ± 95.1 |
2,296.8 ± 38.2 |
2,384.8 ± 80.4 |
1,898.6 ± 94.3 |
1,897.2 ± 88.1 |
1,781.0 ± 289.1 |
|
QS/QT % |
Control Grupo I |
9.8 ± 9.7 |
8.8 ± 6.4 |
8.3 ± 6.4 |
12.8 ± 11.6 |
12.5 ± 12.6 |
15.5 ± 12.5 |
15.5 ± 12.1 |
15 ± 11.1 |
16 ± 10 |
10 ± 13.9 |
15.1 ± 12 |
15.6 ± 11.6 |
AO Grupo II |
21.3 ± 5.9 |
25.1 ± 23.7 |
23.3 ± 23.2 |
32.6 ± 28 |
45.3 ± 35.6 |
41 ± 24.2 |
43.5 ± 22.1 |
46.3 ± 25.4* |
48 ± 24.1* |
56.1 ± 29.5* |
51 ± 24.8* |
52.3 ± 22.3* |
|
L-arginina Grupo III |
24.4 ± 20.8 |
26.8 ± 19.3 |
28 ± 14.7 |
44.6 ± 29.2 |
52.6 ± 24.1 |
55 ± 30.5 |
59 ± 29.1 |
64 ± 16.6* |
65.8 ± 16.9* |
68.8 ± 28.7* |
67.6 ± 11.6* |
68.8 ± 11.9* |
|
* p < 0.05. ANDEVA MR, Dunnett. Promedio ± DE. PVRi = índice de resistencia vascular pulmonar; SVRi = índice de resistencia vascular sistémica; QS/QT = cortocircuito intrapulmonar. |