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Tabla 3: Riesgo atribuible a los marcadores inflamatorios, escalas pronósticas y características ventilatorias con peor pronóstico. |
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|
|
OR (IC 95%) |
p |
|
OR (IC 95%) |
p |
|
PCR ≥ 16 mg/mL |
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|
Mortalidad |
0.8 (0.4-1.6) |
0.62 |
APACHE-II ≥ 25 pts. |
0.9 (0.4-2) |
0.96 |
|
≥ 21 días de |
1 (0.6-1.7) |
0.92 |
SAPS-II ≥ 50 pts. |
0.9 (0.5-1.5) |
0.77 |
|
≥ 15 días en UTIR |
1.2 (0.7-2.1) |
0.36 |
PaO2/FiO2 |
1.2 (1.06-1.5) |
0.05 |
|
≥ 11 días de VMI |
1.2 (0.7-2.2) |
0.43 |
PaCO2 > 50 mmHg |
1.3 (1-1.9) |
0.12 |
|
SOFA ≥ 10 pts. |
1.1 (0.9-1.3) |
0.06 |
Crs’ < 30 mL/cmH2O |
1.1 (0.7-1.7) |
0.57 |
|
PCT ≥ 0.83 ng/mL |
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|
Mortalidad |
2.6 (1.3-4.9) |
< 0.01 |
APACHE-II ≥ 25 pts. |
1.8 (1.3-2.3) |
< 0.01 |
|
≥ 21 días de |
0.9 (0.5-1.6) |
0.74 |
SAPS-II ≥ 50 pts. |
1.2 (1.05-1.5) |
< 0.01 |
|
≥ 15 días en UTIR |
1.3 (0.7-2.4) |
0.30 |
PaO2/FiO2 |
0.8 (0.7-1.1) |
0.25 |
|
≥ 11 días de VMI |
2 (1.1-3.7) |
0.01 |
PaCO2 > 50 mmHg |
1.1 (0.7-1.8) |
0.37 |
|
SOFA ≥ 10 pts. |
1.2 (1-1.5) |
0.01 |
Crs’ < 30 mL/cmH2O |
1.1 (0.9-1.4) |
0.06 |
|
DD ≥ 1,290 ng/mL |
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|
Mortalidad |
1.6 (0.9-3) |
0.11 |
APACHE-II ≥ 25 pts. |
0.7 (0.3-1.5) |
0.17 |
|
≥ 21 días de |
0.9 (0.5-1.6) |
0.86 |
SAPS-II ≥ 50 pts. |
1 (0.9-1.2) |
0.24 |
|
≥ 15 días en UTIR |
1.2 (0.7-2.1) |
0.37 |
PaO2/FiO2 |
1.1 (0.8-1.3) |
0.37 |
|
≥ 11 días de VMI |
1.1 (0.6-1.9) |
0.61 |
PaCO2 > 50 mmHg |
1.1 (0.9-1.4) |
0.16 |
|
SOFA ≥ 10 pts. |
1.1 (0.9-1.2) |
0.17 |
Crs’ < 30 mL/cmH2O |
0.8 (0.5-1.2) |
0.45 |
|
FS ≥ 1,450 ng/mL |
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|
Mortalidad |
0.9 (0.5-1.7) |
0.81 |
APACHE-II ≥ 25 pts. |
1.3 (0.6-2.8) |
0.43 |
|
≥ 21 días de |
0.8 (0.5-1.4) |
0.48 |
SAPS-II ≥ 50 pts. |
1.3 (0.8-2.3) |
0.22 |
|
≥ 15 días en UTIR |
0.9 (0.5-1.6) |
0.87 |
PaO2/FiO2 |
1 (0.8-1.2) |
0.22 |
|
≥ 11 días de VMI |
0.8 (0.5-1.4) |
0.85 |
PaCO2 > 50 mmHg |
0.9 (0.6-1.4) |
0.90 |
|
SOFA ≥ 10 pts. |
1.3 (0.7-2.1) |
0.30 |
Crs’ < 30 mL/cmH2O |
1 (0.6-1.5) |
0.90 |
|
IL6 ≥ 197 pg/mL |
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|
Mortalidad |
1.9 (1-3.6) |
0.03 |
APACHE-II ≥ 25 pts. |
0.6 (0.3-1.3) |
0.23 |
|
≥ 21 días de |
1.3 (0.7-2.2) |
0.29 |
SAPS-II ≥ 50 pts. |
1 (0.9-1.3) |
0.45 |
|
≥ 15 días en UTIR |
1.9 (1.1-3.3) |
0.01 |
PaO2/FiO2 |
1.2 (0.9-1.8) |
0.14 |
|
≥ 11 días de VMI |
1.8 (1-3.2) |
0.02 |
PaCO2 > 50 mmHg |
1 (0.7-1.4) |
0.88 |
|
SOFA ≥ 10 pts. |
1.1 (1-1.3) |
0.05 |
Crs’ < 30 mL/cmH2O |
1.1 (0.7-1.7) |
0.59 |
|
≤ 2 MI altos |
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|
Mortalidad |
0.9 (0.7-1) |
0.08 |
APACHE-II ≥ 25 pts. |
0.9 (0.8-1) |
0.27 |
|
≥ 21 días de |
0.9 (0.7-0.9) |
0.01 |
SAPS-II ≥ 50 pts. |
0.9 (0.8-1.1) |
0.88 |
|
≥ 15 días en UTIR |
0.7 (0.5-0.9) |
0.05 |
PaO2/FiO2 |
0.9 (0.7-1.1) |
0.66 |
|
≥ 11 días de VMI |
0.8 (0.6-1.1) |
0.06 |
PaCO2 > 50 mmHg |
0.9 (0.7-1.1) |
0.70 |
|
SOFA ≥ 10 pts. |
0.9 (0.8-1.1) |
0.54 |
Crs’ < 30 mL/cmH2O |
0.9 (0.8-1.1) |
0.54 |
|
≥ 3 MI altos |
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|
Mortalidad |
1.7 (0.9-3.2) |
0.06 |
APACHE-II ≥ 25 pts. |
1 (0.7-3.4) |
0.27 |
|
≥ 21 días de |
1.3 (1-1.8) |
0.01 |
SAPS-II ≥ 50 pts. |
1 (0.5-1.6) |
0.88 |
|
≥ 15 días en UTIR |
1.6 (1-2.7) |
0.05 |
PaO2/FiO2 |
1 (0.7-1.5) |
0.66 |
|
≥ 11 días de VMI |
1.5 (1-2.6) |
0.05 |
PaCO2 > 50 mmHg |
1 (0.7-1.5) |
0.70 |
|
SOFA ≥ 10 pts. |
1.1 (0.7-1.9) |
0.54 |
Crs’ < 30 mL/cmH2O |
1.1 (0.7-1.7) |
0.54 |
|
OR = razón de momios. IC 95% = intervalo de confianza de 95%. PCR = proteína C reactiva. UTIR = Unidad de Terapia Intensiva Respiratoria. VMI = ventilación mecánica invasiva. SOFA = sequential organ failure assessment. PCT = procalcitonina. DD = dímero D. FS = ferritina. IL6 = interleucina-6. MI = marcadores inflamatorios. APACHE-II = Acute Physiology and Chronic Health Evaluation II. SAPS-II = Simplified Acute Physiology Score II. |
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