|
Tabla 2: Distribución de la población en grupos con marcadores inflamatorios altos y bajos. |
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|
N = 218 |
PCR [mg/mL] |
|
PCT [ng/mL] |
|
DD [ng/mL] |
|
FS [ng/mL] |
|
IL6 [pg/mL] |
|
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|
< 16 |
≥ 16 |
p |
OR (IC 95%) |
< 0.83 |
≥ 0.83 |
p |
OR (IC 95%) |
< 1,291 |
≥ 1,291 |
p |
OR (IC 95%) |
< 1,450 |
≥ 1,450 |
p |
OR (IC 95%) |
< 195 |
≥ 195 |
p |
OR (IC 95%) |
|
|
123 (56.4) |
95 (43.6) |
152 (69.7) |
66 (30.3) |
121 (55.5) |
97 (44.5) |
106 (48.6) |
115 (51.4) |
120 (55.0) |
98 (45.0) |
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|
n (%) |
n (%) |
n (%) |
n (%) |
n (%) |
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|
Hombres |
96 (78.0) |
73 (76.8) |
0.83 |
0.9 (0.5-1.7) |
118 (77.6) |
51 (77.3) |
0.95 |
0.9 (0.5-1.9) |
95 (78.5) |
74 (76.3) |
0.70 |
0.8 (0.4-1.6) |
70 (66.0) |
99 (86.0) |
< 0.05 |
3.9 (1.9-7.9) |
93 (77.5) |
76 (77.6) |
0.99 |
1 (0.5-1.9) |
|
≥ 60 años |
62 (50.4) |
53 (55.8) |
0.43 |
1.2 (0.7-2.1) |
80 (52.6) |
35 (53.0) |
0.96 |
1 (0.5-1.8) |
55 (45.5) |
60 (61.9) |
0.06 |
1.9 (1.1-3.3) |
62 (58.5) |
53 (46.0) |
0.10 |
0.6 (0.37-1) |
59 (49.2) |
56 (57.1) |
0.24 |
1.3 (0.8-2.3) |
|
IMC ≥ 28 kg/m2 |
63 (51.2) |
44 (46.3) |
0.47 |
0.8 (0.5-1.4) |
78 (51.3) |
29 (44.0) |
0.32 |
0.7 (0.4-1.3) |
63 (52.1) |
44 (45.4) |
0.33 |
0.7 (0.4-1.3) |
60 (56.6) |
47 (40.9) |
0.03 |
0.5 (0.3-0.9) |
61 (50.8) |
46 (46.9) |
0.57 |
0.8 (0.5-1.4) |
|
Comorbilidades |
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|
DM tipo 2 |
25 (20.3) |
32 (33.7) |
0.26 |
2 (1-3.6) |
31 (20.4) |
26 (39.4) |
< 0.05 |
2.5 (1.3-4.7) |
28 (23.1) |
29 (29.9) |
0.26 |
1.4 (0.7-2.6) |
32 (30.2) |
25 (21.7) |
0.19 |
0.6 (0.3-1.2) |
28 (23.3) |
29 (29.6) |
0.30 |
1.3 (0.7-2.5) |
|
HAS |
64 (52.0) |
46 (48.4) |
0.60 |
0.8 (0.5-1.5) |
78 (51.3) |
32 (48.5) |
0.70 |
0.9 (0.5-1.6) |
58 (47.9) |
52 (53.6) |
0.41 |
1.2 (0.7-2.1) |
60 (56.6) |
50 (43.4) |
0.08 |
0.6 (0.3-1) |
61 (50.8) |
49 (50.0) |
0.90 |
0.9 (0.5-1.6) |
|
Tabaquismo |
32 (26.0) |
23 (24.2) |
0.76 |
0.9 (0.48-1.7) |
40 (26.3) |
15 (22.7) |
0.58 |
0.8 (0.4-1.6) |
32 (26.4) |
23 (23.7) |
0.64 |
0.8 (0.4-1.6) |
27 (25.5) |
28 (24.3) |
0.94 |
0.9 (0.52-1.79) |
36 (30.0) |
19 (19.4) |
0.07 |
0.5 (0.3-1) |
|
Escalas pronósticas |
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|
SOFA ≥ 10 pts. |
21 (17.1) |
26 (27.4) |
0.07 |
1.8 (1-3.5) |
25 (16.4) |
22 (33.3) |
< 0.05 |
2.5 (1.3-5) |
22 (18.2) |
25 (25.8) |
0.18 |
1.5 (0.8-2.9) |
26 (24.5) |
21 (18.2) |
0.30 |
0.7 (0.3-1.35) |
20 (16.7) |
27 (27.6) |
0.05 |
1.9 (1-3.6) |
|
APACHE-II ≥ 25 pts. |
14 (11.4) |
11 (11.6) |
0.96 |
1 (0.4-2.36) |
15 (9.9) |
10 (15.2) |
0.26 |
1.6 (0.7-3.8) |
12 (9.9) |
13 (13.4) |
0.42 |
1.4 (0.6-3.2) |
14 (13.2) |
11 (9.5) |
0.43 |
0.7 (0.3-1.6) |
11 (9.2) |
14 (14.3) |
0.24 |
1.6 (0.7-3.8) |
|
SAPS-II ≥ 50 pts. |
24 (19.5) |
20 (21.1) |
0.78 |
1.1 (0.6-2.1) |
22 (14.5) |
22 (33.3) |
< 0.05 |
3 (1.5-5.8) |
21 (17.4) |
23 (23.7) |
0.25 |
1.4 (0.7-2.8) |
25 (23.6) |
19 (16.5) |
0.22 |
0.6 (0.3-1.3) |
22 (18.3) |
22 (22.4) |
0.45 |
1.2 (0.6-2.5) |
|
Ventilación |
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|
PaO2 ≤ 150 mmHg |
82 (66.7) |
51 (53.7) |
0.05 |
0.6 (0.33-1) |
89 (58.6) |
44 (66.7) |
0.26 |
1.4 (0.7-2.6) |
77 (63.6) |
56 (57.7) |
0.37 |
0.7 (0.4-1.3) |
64 (60.4) |
69 (60.0) |
0.85 |
1 (0.6-1.8) |
68 (56.7) |
65 (66.3) |
0.15 |
1.5 (0.8-2.6) |
|
PaCO2 > 50 mmHg |
50 (40.7) |
29 (30.5) |
0.12 |
0.6 (0.3-1.1) |
58 (38.2) |
21 (31.8) |
0.37 |
0.7 (0.4-1.4) |
39 (32.2) |
40 (41.2) |
0.17 |
1.4 (0.8-2.5) |
38 (35.8) |
41 (35.6) |
0.91 |
1 (0.6-1.8) |
44 (36.7) |
35 (35.7) |
0.88 |
0.9 (0.5-1.6) |
|
Crs’ < 30 mL/cmH2O |
38 (30.9) |
26 (27.4) |
0.57 |
0.8 (0.5-1.5) |
39 (25.7) |
25 (37.9) |
0.07 |
1.7 (1-3.2) |
33 (27.3) |
31 (32.0) |
0.45 |
1.2 (0.7-2.2) |
31 (29.2) |
33 (28.7) |
0.97 |
1 (0.5-1.8) |
37 (30.8) |
27 (27.6) |
0.60 |
0.8 (0.4-1.5) |
|
PCR = proteína C reactiva. PCT = procalcitonina. DD = dímero D. FS = ferritina. IL6 = interleucina-6. IMC = índice de masa corporal. DM = diabetes mellitus. HAS = hipertensión arterial sistémica. SOFA = sequential organ failure assessment. APACHE-II = Acute Physiology and Chronic Health Evaluation II. SAPS-II = Simplified Acute Physiology Score II. |
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