Tabla 2: Evolución de los parámetros de laboratorio, gasométricos, ventilatorios y manejo en los primeros 7 días de ventilación mecánica invasiva. |
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Parámetros |
Al ingreso |
Día 1 |
Día 2 |
Día 3 |
Día 4 |
Día 5 |
Día 6 |
Día 7 |
Gasométricos |
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Lactato, mmol/L [RIC] |
1.3 [0.5] |
1.6 [0.5] |
1.7 [0.8] |
1.6 [0.7] |
1.5 [0.6] |
1.7 [0.7] |
1.5 [0.6] |
1.5 [0.3] |
pH |
7.34 ± 0.07 |
7.36 ± 0.07 |
7.39 ± 0.03 |
7.41 ± 0.03 |
7.43 ± 0.03 |
7.41 ± 0.03 |
7.41 ± 0.02 |
7.40 ± 0.05 |
PaO2, mmHg |
87 ± 24.0 |
86 ± 19.0 |
79 ± 13.00 |
84 ± 15.0 |
79 ± 14.00 |
84 ± 23.00 |
78 ± 13.00 |
75 ± 13.00 |
PaCO2, mmHg |
42 ± 6.2 |
42 ± 7.4 |
42 ± 4.80 |
41 ± 6.70 |
38 ± 6.50 |
40 ± 5.70 |
40 ± 3.80 |
42 ± 6.40 |
FiO2, % [RIC] |
65 [35] |
50 [16] |
45 [15] |
40 [10] |
40 [13] |
37 [9] |
42 [7] |
40 [2] |
PaO2/FiO2, mmHg/% |
135 ± 53.0 |
184 ± 59.0 |
176 ± 54.00 |
209 ± 58.0 |
209 ± 56.00 |
228 ± 65.00 |
195 ± 39.00 |
191 ± 36.00 |
Ventilatorios |
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VT, mL/kg |
454 ± 42.0 |
437 ± 33.0 |
442 ± 43.00 |
452 ± 88.0 |
435 ± 44.00 |
439 ± 48.00 |
439 ± 61.00 |
455 ± 57.00 |
Vt/kg predicho, mL/kg |
6.6 ± 0.9 |
6.5 ± 0.8 |
6.5 ± 0.70 |
6.7 ± 1.3 |
6.5 ± 0.70 |
6.5 ± 0.50 |
6.6 ± 0.90 |
6.7 ± 0.90 |
FR, rpm |
20 ± 1.2 |
21 ± 1.7 |
21 ± 2.10 |
21 ± 1.1 |
21 ± 1.30 |
21 ± 1.50 |
20 ± 1.40 |
21 ± 2.30 |
PEEP, cmH2O [RIC] |
12 [2] |
10 [0.8] |
9.5 [2] |
8 [2] |
8 [3] |
8 [2.3] |
8 [2.8] |
8 [2.5] |
Presión pico, cmH2O |
28 ± 5.1 |
26 ± 3.8 |
26 ± 3.50 |
25 ± 3.3 |
25 ± 3.90 |
24 ± 4.00 |
24 ± 5.20 |
24 ± 4.40 |
Presión meseta, cmH2O |
26 ± 4.8 |
24 ± 3.5 |
24 ± 3.20 |
23 ± 2.9 |
23 ± 2.80 |
23 ± 3.60 |
24 ± 4.30 |
24 ± 4.00 |
Cest, mL/cmH2O |
32 ± 8.5 |
34 ± 8.0 |
33 ± 8.70 |
33 ± 7.3 |
32 ± 7.10 |
32 ± 8.70 |
28 ± 6.80 |
33 ± 9.70 |
Presión de distensión, cmH2O |
15 ± 3.9 |
14 ± 2.9 |
14 ± 3.30 |
14 ± 3.1 |
14 ± 2.20 |
15 ± 2.90 |
16 ± 3.90 |
15 ± 4.10 |
Poder mecánico, J/min |
19.2 ± 4.0 |
17.8 ± 2.9 |
17.9 ± 3.30 |
18.6 ± 4.8 |
17.1 ± 2.40 |
16 ± 2.20 |
16.7 ± 3.80 |
19.2 ± 4.50 |
RIC = rango intercuartilar; PaO2 = presión arterial de oxígeno; PaCO2 = presión arterial de dióxido de carbono; FiO2 = fracción inspirada de oxígeno; PaO2/FiO2 = relación PaO2/FiO2; VT = volumen corriente; FR = frecuencia respiratoria; PEEP = presión positiva al final de la espiración; Cets = distensibilidad estática. |