Tabla 3: Comparación de variables entre grupos. |
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Variable |
Sin ventilación mecánica (N = 49) |
Ventilación mecánica (N = 102) |
Total (N = 151) |
p |
Edad, mediana (IQR) años |
50 (43-55) |
55 (45.3-65.8) |
52 (45-64) |
0.01 |
Sexo masculino, n (%) |
30 (61.2) |
75 (73.5) |
105 (69.5) |
0.1 |
IMC, mediana (IQR) kg/m2 |
28.6 (25.5-33.2) |
30.3 (25.7-36.6) |
29.3 (25.5-34.7) |
0.2 |
Tabaquismo, n (%) |
17 (34.7) |
21 (20.6) |
38 (25.2) |
0.09 |
Alcoholismo, n (%) |
18 (36.7) |
16 (15.7) |
34 (22.5) |
0.007 |
Comorbilidades, n (%) |
25 (51) |
66 (64.7) |
91 (60.3) |
0.1 |
EPOC, n (%) |
1 (2) |
4 (3.9) |
5 (3.3) |
0.9 |
Diabetes, n (%) |
12 (24.5) |
45 (44.1) |
57 (37.7) |
0.03 |
Hipertensión arterial, n (%) |
14 (28.6) |
42 (41.2) |
56 (37.1) |
0.1 |
Enfermedad coronaria, n (%) |
1 (2) |
1 (0.9) |
2 (1.3) |
1 |
Enfermedad renal crónica, n (%) |
1 (2) |
5 (4.9) |
6 (4) |
0.6 |
Hipotiroidismo, n (%) |
1 (2) |
5 (4.9) |
6 (4) |
0.6 |
Asma, n (%) |
5 (10.2) |
1 (0.9) |
6 (4) |
0.02 |
Fiebre, n (%) |
39 (79.6) |
85 (83.3) |
124 (82.1) |
0.7 |
Cefalea, n (%) |
25 (51) |
37 (36.3) |
62 (41.1) |
0.1 |
Tos, n (%) |
40 (81.6) |
73 (71.6) |
113 (74.8) |
0.2 |
Fatiga, n (%) |
12 (24.5) |
21 (20.6) |
33 (21.9) |
0.7 |
Disnea, n (%) |
37 (75.5) |
87 (85.3) |
124 (82.1) |
0.2 |
Náusea/vómito, n (%) |
7 (14.3) |
9 (8.8) |
16 (10.6) |
0.4 |
Diarrea, n (%) |
7 (14.3) |
13 (12.7) |
20 (13.2) |
0.9 |
Mialgia, n (%) |
23 (46.9) |
44 (43.1) |
67 (44.4) |
0.7 |
Artralgia, n (%) |
19 (38.7) |
37 (36.3) |
56 (37.1) |
0.9 |
Relación PaO2/FiO2, mediana (IQR) |
285 (228-314) |
183 (94.3-259) |
219 (131-285) |
< 0.001 |
Leucocitos, mediana (IQR) - por mm3 |
8,900 (7,100-11,200) |
12,500 (9,400-16,400) |
11,200 (8,200-15,350) |
< 0.001 |
Plaquetas, media (± DE) por mm3 |
305,102 (163,838) |
251,752 (89,593) |
269,180 (121,099) |
0.9 |
Hemoglobina, mediana (IQR) g/dL |
14.3 (13.7-15.4) |
14.6 (13-15.5) |
14.4 (13-15.4) |
0.4 |
Proteína C-reactiva, media (± DE) mg/dL |
15.1 (11.1) |
26.6 (11.6) |
22.8 (12.6) |
1 |
Procalcitonina, mediana (IQR) ng/mL |
0 (0-0.5) |
0.5 (0-2) |
0.5 (0-2) |
< 0.001 |
DHL, mediana (IQR) -U/L |
338 (240-396) |
477 (374-608) |
406 (322-567) |
< 0.001 |
0.8 (0.6-0.9) |
0.9 (0.7-1.53) |
0.9 (0.7-1.4) |
< 0.001 |
|
938 (498-2220) |
2,120 (817-3,400) |
1,650 (739-3,345) |
0.001 |
|
Glucosa, mediana (IQR) mg/dL |
103 (90-134) |
139 (100-216) |
126 (94.3-203) |
< 0.001 |
Estancia intrahospitalaria, mediana (IQR) días |
9 (7-14) |
6 (4-9) |
7 (4-11) |
< 0.001 |
PSI/PORT, mediana (IQR) |
60 (47-71) |
91.5 (73.3-119) |
83 (60-108) |
< 0.001 |
SOFA, mediana (IQR) |
2 (2-2) |
3 (2-3) |
2 (2-3) |
< 0.001 |
Defunción, n (%) |
5 (10.2) |
97 (95) |
102 (67.5) |
< 0.001 |
IQR = rango intercuartil, IMC = índice de masa corporal, EPOC = enfermedad pulmonar obstructiva crónica, DHL = deshidrogenasa láctica, SOFA = Sequential Organ Failure Assessment. *Rangos normales: Relación PaO2/FiO2, > 300; leucocitos, 4,600-10,200/mm3; plaquetas, 142,000-424,000/mm3; hemoglobina, 12.2-18.1 g/dL; proteína C reactiva, 0-0.7 mg/dL; procalcitonina, 0-0.5 ng/mL; deshidrogenasa láctica, 100-170 U/L; creatinina, 0.8-1.4 mg/dL; dímero-D, 0- 400 ng/mL; glucosa, 70-110 mg/dL. |